查询词典 collagen

Hematoxylin and eosin, Alcian blue, Masson Trichrome, and Elastica Van Giesonstains were performed for each LF. Nine LF were collected and were used for biologic study of real time RT-PCR to quantitatively measure mRNA expression of Type I collagen and elastin in each LF.

每份标本用HE染色、Alcian蓝染色， Masson Trichrome染色以及Elastica Van Gieson染色。9份标本染色后收集，用实时定量PCR定量分析每份标本中I 型胶原纤维和弹力纤维的mRNA的表达。

Third, as suggested in the study of human cells, the ellagic acid reduced inflammatory response and MMP secretion due to protection from the degradation of collagen.

第三，与人类细胞试验结果一样，鞣花酸可以减轻炎症反应，减少MMP分泌，以此保护胶原蛋白不被降解。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

The morphologic change of muscle fibers: At the early stage of denervation, the area of cross sections decreased, some muscle fibers turned into angular fibers, nuclei congregated around the center of the fibers. After 8 weeks of denervation, atrophic and hypertrophic fibers coexist. Collagen increases under the endomysium and between the fibers.

肌纤维的组织形态学变化：面部肌肉失神经支配早期，肌纤维的横截面面积变小，出现角状纤维，肌细胞核聚集，细胞核从肌纤维边缘移至肌纤维中央附近；失神经支配后期，肿胀与萎缩的肌纤维并存，肿胀的肌纤维的横截面成倍大于正常的肌纤维，而萎缩的肌纤维的横截面则成倍小于正常的肌纤维；有大量的角纤维存在，肌纤维之间有较多的结缔组织增生。

CD34 hematopoietic stem/progenitor cells reside in the bone marrow in close proximity to the endosteal bone surface, surrounded by osteoblasts, stromal cells, and various extracellular matrix molecules. We used a bioartificial matrix of fibrillar collagen I, the major matrix component of bone, as a scaffold for ex vivo expansion of HSCs.

CD34 的造血干细胞/祖细胞存在于接近骨内膜表面的骨髓中，由成骨细胞、间充质细胞以及各种细胞外基质分子所包绕，我们采用生物人工合成的纤维胶原I

CD34+ hematopoietic stem/progenitor cells reside in the bone marrow in close proximity to the endosteal bone surface, surrounded by osteoblasts, stromal cells, and arious extracellular matrix molecules. We used a bioartificial matrix of fibrillar collagen I, the major matrix component of bone, as a scaffold for ex io expansion of HSCs.

CD34+的造血干细胞/祖细胞存在于接近骨内膜表面的骨髓中，由成骨细胞、间充质细胞以及各种细胞外基质分子所包绕，我们采用生物人工合成的纤维胶原I

Objective To investigate the effect of glycation of collagen Ⅳ on biological character of epidermal stem cells.

目的 研究糖尿病患者皮肤组织中Ⅳ型胶原的糖基化对表皮干细胞生物学特性的影响。

Second, to study the effect of antler collagen protein on Vero, L_(929), human cervix cancer, rat osteoblast cells and epidermic cells.

研究鹿茸Ⅰ型胶原蛋白对Vero、L_(929)、人宫颈癌细胞Hela、Wistar大鼠成骨细胞和表皮细胞贴壁及增殖的影响。

Results:Wound healing rate in group A was higher than that in group B and the wound healing time was 1～3 days earlier in group A.More active proliferation of epidermic cells around wounds showed in group A.The function of fibroblasts in wounds,collagen synthesis and secretion,were more vigorous in group A than those in group B.

结果：A组创面愈合率高于B组，其创面愈合时间较B组提前1～3 d；创周表皮细胞增殖也较B组活跃，创面成纤维细胞较B组呈现出更旺盛的合成与分泌胶原纤维的功能。

Different peeling solutions produce different influence on skin tissue, which show respectively:regular rearrangement of epidermic cells, proliferation and rearrangement of collagen, increase of the thickness of epidermis and decrease of melanocytes.

不同剥脱剂对皮肤产生不同的组织学影响，分别表现在对表皮细胞、胶原组织、黑素细胞等的影响上。

You can do some assertiveness training.

你可以进行一些自信训练。

We were well on the path to making a rear-wheel-drive global platform," says Mays."

我们正致力于建立一个后轮驱动的平台，"Mays这样说道。"