查询词典 cofactors

Two separate cofactors have been utilized to perform this decarboxylation.

两个独立的辅助因子已被用来执行此脱羧。

Types of hydrogenase are reviewed,i ts applications have found its appli cations,such as biohydrogen production,wastewater treatment,prevention of microbial-induced corrosion,generation and regeneration of NADP cofactors.

介绍了氢化酶的类型，讨论了氢化酶在生物制氢、废水处理、预防微生物腐蚀、NADP辅因子的产生及其再生等生物技术领域中的应用。

In lacteal cell, ER control genetic expression by recruiting transcriptional cofactors, for HATs and HDACs example, which exhibit various enzymatic activities.

在乳腺细胞中，ER正是通过募集如HATs和HDACs等转录共调节因子，利用它们呈现的各种酶活性来调控基因的表达。

PIAS proteins play roles mainly through two mechanisms: acting as SUMO E3 ligases to promote modifications of some transcriptional factors and cofactors, especially sumoylation, and to regulate their transcriptional activation; acting as structural proteins to offer platforms for protein-protein interactions and to promote the abstraction and recruitment of other regulators in the cellular signal pathway complexes or gene transcriptional complexes, companied by the subnuclear location of target proteins.

PIAS蛋白的调控机制主要有两种：一种是通过其自身所具有的SUMO(small ubiquitin-related modifiers)E3连接酶活性，促进对一些转录因子、转录辅因子的化学修饰，尤其是SUMO化修饰，从而调控它们的转录活性；另一种是作为构架蛋白，为蛋白质之间的相互作用提供平台，促进细胞信号通路复合物或基因转录复合物中其它调节蛋白的去除和募集，并涉及到靶蛋白的亚核定位。

Trichomonas vaginalis is one of the most common non-viral sexually transmitted disease, and trichomoniasis is emerging as one of the most important cofactors in amplifying HIV transmission, also linked to this disease are cervical cancer and infertility.

阴道鞭毛虫为WHO宣布为最广泛的非病毒性性接触传染疾病，已证实会造成HIV感染机率增加、与子宫颈癌、不孕症有关联性，且其细胞周期的G2期较G1期长，但对阴道鞭毛虫的仍不清楚。

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

During embryonic development, Hox proteins can interact with different cofactors and regulate downstream gene expression in a tissue specific manner.

在胚胎发育过程中，Hox蛋白实现时间特异性及组织特异性基因表达调控功能的机制之一是与不同的辅助因子相结合。

Pyridoxine, pyridoxal , pyridoxamine as well as their phosphated forms are structural analogues in which pyridoxal-5"-phosphate and pyridoxamine-5"- phosphate are the biological active forms in vivo which act as the cofactors of aminotransferases, amino acid decarboxylases, cysteine desufbrase and cystathionine , etc by constant transconversions. Recently, it was discovered that B6 played a novel role in tumor growth suppression.

它包括三种结构十分近似的化合物：吡哆醇(Pyidoxine，PN)、吡哆醛(Pyridoxal，PL)和吡哆胺(Pyridoxamine，PM)，分别以磷酸化的形式发挥作用，其中吡哆醛-5'-磷酸(Pyridoxal-5'-phosphate，PLP)为B_6在体内的活性形式，通过与磷酸吡哆胺(Pyidoxamine-5-phosphate，PMP)的互变，作为多种酶(氨基转移酶、氨基酸脱羧酶、半胱氨酸脱硫酶、胱硫醚酶等)的辅酶而发挥传递基团的作用。

Part Ⅲ Expression of an iron-superoxide dismutase from camphor seeds, resubstitution of the metal cofactors and the simulated structure Abstract

第三部分：樟树种子超氧化物歧化酶基因的克隆，表达与其金属配基的置换与结构模拟

Apoenzyme: The protein portion of an enzyme, exclusive of any organic or inorganic cofactors or prosthetic groups that might be required for catalytic activity.

多功能酶或串联酶：一些多酶体系在进化过程中由于基因的融合，多种不同催化功能存在于一条多肽链中，这类酶称为多功能酶。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。