查询词典 clofibrate

What are the principles of the identification of clofibrate

氯贝丁酯的鉴别原理是什么？

As is turns out, Clofibrate does have a rather potent activity as an inhibitor of cholesterol synthesis.

正如结果所表明的那样，安托他命作为一种胆固醇合成的抑制剂，确实是相当有疗效。

Treatment of hepatocytes with clofibrate caused a significant increase in intracellular and mitochondrial ROS.

用氯贝丁酯处理过的肝细胞及线粒体内自由基显著增加。

Kunming, China Yunnan Pu'er Tuo medical treatment also were 55 cases of high-fat leukemia clinical trials, and with lipid-lowering effect drug Clofibrate treatment of 31 cases compared the efficacy of tea than Clofibrate.

中国昆明医学院也对云南普洱沱茶治疗高脂血病作了55例临床试验，并与降脂效果较好的药物安妥明治疗的31例对比，普洱茶的疗效高于安妥明。

Kunming Medical College of China also observed 55 clinical trials to use Yunnan Pu'er Tuo tea to cure the high blood fat diseases and compare them with 31 cases used clofibrate which has a good effect to incline fat. The result shows that the curative effect of Pu'er Tea is higher than clofibrate.

中国昆明医学院也对云南普洱沱茶治疗高脂血病作了55例临床试验，并与降脂效果较好的药物安妥明治疗的31例对比，普洱茶的疗效高于安妥明。

The rats in the normal control group were fed with basic feed. The rats in the high-lipid model group were fed with highlipid feed. Rats in the TF group and clofibrate group were fed synchronously with high-lipid feed and total flavonoids or clofibrate for consecutive 30 days.

正常对照组饲喂基础饲料，高脂模型组饲喂高脂饲料，总黄酮大、中、小剂量组和氯苯丁酯组，在喂高脂饲料的同时给予相应剂量的药物。

The results indicated the increases of CAT and GSH-PX activities,and the dec eases of protein contents in renal homogenates of TNT-exposed group and clofibrate-treated group were significantly in comparetion with those of the control(P＜0.05).It indicated that both TNT and clofibrate could induce the production of H2O2 in renal tissues.

结果表明，TNT染毒组、阳性对照组大鼠肾匀浆CAT与GSH-PX活性显著高于对照组(P＜0.05)，而肾蛋白含量显著降低(P＜0.05)，表明TNT染毒和安妥明处理均可诱导肾组织过氧化氢生成。

Methods Twenty four female Zucker rats were divided into four groups: lean rats + vehicle, lean rats + clofibrate, obese rats + vehicle, obese rats + clofibrate. Daily intraperitoneal injection of clofibrate (300 mg/kg) or vehicle (olive oil, 1 mL/kg) was given to the rats for two weeks.

选择瘦型和肥胖型Zucker大鼠24只，分为：瘦大鼠＋赋形剂组，瘦大鼠＋氯苯丁酯组，肥胖大鼠＋赋形剂组和肥胖大鼠＋氯苯丁酯组，分别给予腹腔内注射抓苯丁酯(300mg/kg)或赋形剂（橄榄油，1mL/kg）2周。

Results Clofibrate normalized plasma free fatty acid and cholesterol and reduced plasma triglyceride and insulin in obese rats. However, clofibrate led to accumulation of heart TG and increased myocardial long-chain unsaturated and monounsaturated fatty acids in obese rats. Conclusion Clofibrate aggravates myocardial triglyceride accumulation in female obese Zucker rats.

结果 氯苯丁酯可使肥胖大鼠血浆游离脂肪酸和胆固醇浓度恢复正常并可降低血浆甘油三酯和胰岛素浓度，可增加肥胖大鼠心肌甘油三酯的积聚，且心肌长链不饱和脂肪酸和单不饱和脂肪酸含量也相应增加。

In diabetic mice group: either 250mg/Kg/dayfor 8 days or 500mg/Kg/dayfor 8 days treatment, no clofibrate preparation could decrease serum level of triglyceride or cholesterol. Therefore, alloxan induced diabetic miceis not a good model for evaluating hypolipidemic effects of clofibrate preparations.

但投与250mg/kg/day或500mg/kg/day各8日，对由Alloxan诱发糖尿病之雄性小鼠其胆固醇、三酸甘油脂值，则都没有显著地降低效果，显示以Alloxan诱发糖尿病雄性小鼠为试验模式，不是评估Clofibrate制剂降血脂药效的适当方法。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。