查询词典 chromosome

Based on the cDNA sequence of the zfh -1 gene in Drosophila , a novel human homolog located on chromosome 9 was found by computer cloning method.

利用果蝇心脏发育基因 zfh-1的 c DNA序列和计算机克隆方法，在 9号染色体上发现了一个新的人类同源基因。

Objective To detect and analysis epidermal growth factor receptor and phosphatase and tensin homolog deleted on chromosome ten in different malignancy brain tumors, and to evaluate their prognostic significance.

目的 探讨表皮生长因子受体和抑癌基因―人10号染色体上缺失的磷酸酶和张力蛋白类似物在常见恶性脑肿瘤中的表达及与脑肿瘤预后的关系。

AIM: To investigate the correlation of phosphatase and tensin homolog deleted on chromosome ten protein expression and clinicopathological features in the precancerous lesions and early gastric cancer, and to explore its clinical implication in early development of gastric cancer.

目的：观察正常胃黏膜、肠上皮化生、异型增生和早期胃癌中抑癌基因PTEN的蛋白表达，探讨PTEN表达在胃癌早期发生过程中的作用。

Abundance orA repeats was similar to C repeats. AC was a little more than two times as abundant much as AG. However, AT and CG repeats were rare. For tri- and tetramer repeats, AGC,AAAC and AAAT predominated while ACG, ACT, AGG, CCG, ATGC, CCCG, ACTG, AACT, ACGT, AGAT, CCGG,ACCT and AGCT were rare. For some pentamer repeats, one was completely absent on a certain chromosome, even on several chromosomes.

对按蚊基因组中微卫星丰度而言，A碱基和C碱基重复在基因组中丰度相似，AC单元的丰度是AG单元的两倍多，然而AT和CG单元非常稀少；对于三四碱基而言，AGC，AAAC和AAAT单元最为丰富，ACG，ACT，AGG，CCG，ATGC，CCCG，ACTG，AACT，ACGT，AGAT，CCGG，ACCT和AGCT单元等均很稀少，而一些五碱基重复，在某条甚至某几条染色体中均未分布。

Dr Venter described his achievement as the creation of life "totally derived from a synthetic chromosome, made with four bottles of chemicals on a chemical synthesiser".

凡特把他这项成就形容为创造生命，&完全得自于一个合成染色体，用了4瓶化学品，在一个化学合成器上制成的&。

Importantly, repression of PinX1 and Nucleolin abrogates chromosome segregation in real-time mitosis, validating the functional importance of PinX1-Nucleolin interaction.

实时图像数据表明，当PinX1和Nucleolin的表达同时被抑制时，染色体的分离不能正常进行。

In summary, the BRD7 gene acted as a candidate of tumor suppressor gene with NPC. The overexpression of BRD7 can partly reverse malignant phenotype of NPC cell line. The suppression effect of BRD7 on NPC tumorigenesis my be achieved by recognizing acetylated histone peptide through their motif-bromodomain, then modulating gene transcription by taking part in histone acetylating and chromosome remodeling, finally influencing signal-transduction pathways.

综上所述，BRD7基因作为一个重要的鼻咽癌抑瘤基因侯选者，在鼻咽癌细胞中的过表达后，可导致鼻咽癌细胞 HNE蛋白质表达谱发生改变，逆转其恶性表型，其作用机理可能是：BRD7基因通过其功能域彭聪硕士学位论文10Bromodomain与乙酚化的组蛋白特异性结合，参于染色体的乙酚化，染色质的组装，从而影响基因转录的调控，最终影响细胞内的信号传导通路并实现对细胞周期的调控，从而发挥抑制鼻咽癌细胞生长的作用。

Objective To study the technique and diagnostic value of fluorescence insitu hybridization in chromosome abnormality for prenatal diagnosis. Methods Amniocenteses were performed in 34 pregnant women of 16～23 gestational weeks with indications for prenatal diagnosis. The amniotic fluid samples were cultured in Chang's medium.

荧光原位杂交(fluorescence in situ hybridization， FISH)是分子杂交与组织化学相结合的一项新技术，近年来用于人类染色体分析，它能快速、准确地确定在传统方法中无法判别的染色体异常，特别对来源不明的标记染色体能作出正确诊断［1，2］。

Second Municipal People's Hospital of Guangzhou, Guangzhou 510150 Objective To study the technique and diagnostic value of fluorescence insitu hybridization in chromosome abnormality for prenatal diagnosis. Methods Amniocenteses were performed in 34 pregnant women of 16～23 gestational weeks with indications for prenatal diagnosis. The amniotic fluid samples were cultured in Chang's medium.

对34例孕16～23周有产前诊断指征者经腹部抽取羊水，用Chang培养液传代培养，常规制备羊水细胞分裂中期染色体，应用生物素及地高辛标记的人类全着丝粒探针和X、Y、13、21、18号染色体α-着丝粒探针及染色体全涂染探针，与培养的羊水细胞分裂中期染色体DNA进行原位杂交，杂交后用荧光显微镜观察玻片并摄像。

Methods Amniocenteses were performed in 34 pregnant women of 16～23 gestational weeks with indications for prenatal diagnosis. The amniotic fluid samples were cultured in Chang's medium. The metaphase chromosomes were hybridized insitu with the human centromere probes,α-satellites DNA probes of X, Y,13, 21, 18 chromosomes and all primer chromosome probes. These probes were conjugated by Biotin and Dioxin then. The treated slides were examined and taken photos under the fluoromicroscope.

对34例孕16～23周有产前诊断指征者经腹部抽取羊水，用Chang培养液传代培养，常规制备羊水细胞分裂中期染色体，应用生物素及地高辛标记的人类全着丝粒探针和X、Y、13、21、18号染色体α-着丝粒探针及染色体全涂染探针，与培养的羊水细胞分裂中期染色体DNA进行原位杂交，杂交后用荧光显微镜观察玻片并摄像。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。