查询词典 chromatin

Then the caprine fetal fibroblast cells were transfected with p6.5hLF-EGFP by LipofectamineTM-2000 and selected by G418 for 3 to 4 weeks. The G418 resistant transfectants were identified by PCR and EGFP detection. The results indicated that the transgene was stably integrated into the open region of the chromatin of G418 resistant fibroblast cells.

脂质体介导法转染山羊胎儿成纤维细胞，G418抗性筛选3-4周后，经PCR扩增和报告基因EGFP表达检测，得到稳定整合外源基因的转基因供体细胞系，为制备高效表达人乳铁蛋白的转基因山羊乳腺生物反应器提高可靠的核移植供体细胞。

Figure 6 Bright fluorescence of condensed nuclear chromatin appeared around circumnuclear edge of apoptotic osteoclast,nonapoptotic nuclear fluorescence showed coherent distributed.

凋亡细胞核核周呈一亮环，而未凋亡细胞核染色均一（图6）。图6 凋亡破骨细胞胞核周缘呈环状亮色，而未凋亡细胞核荧光染色均一。

The type of cell death caused by ricin was related to the ricin concentration and time of incubation with HeLa cells. The typical apoptosis was induced by ricin 0.05μmol〓. The apoptotic cells mainly showed cell shrinkage, cytoplasmic membrane blebbing, the chromatin condensation and fragmentation, crescentic nuclear and membrane bound apoptotic bodies formation.

细胞死亡方式也与蓖麻毒素作用时间和浓度相关，0.05μmol.L〓的蓖麻毒素可引起HeLa细胞发生典型的细胞凋亡，主要特征是细胞体积缩小，胞浆起泡，细胞核染色质浓缩、凝集，新月状核和膜包裹核染色质的凋亡小体形成。

The neoplastic epithelia are low cuboidal and not columnar in shape, with very large and atypical oval nuclei with vesicular chromatin and prominent nucleoli.

肿瘤性上皮呈低立方状而不是柱状，有很大的卵圆形核和显著核异型性，空泡状染色质和显著核仁。

The duration and temperature during ovary transportation and handling might, therefore, affect the recovery of culturable COCs, chromatin configuration and developmental competence of oocytes.

在具体的实施过程中，从屠宰场向实验室运输卵巢、卵母细胞培养前操作等都需要一定的时间，这可能会对卵母细胞的回收率、卵母细胞成熟质量、甚至受精后的发育产生不良影响。

By means of the transmission electron microscope we found the typical morphology variation of apoptosis,such as the concentration and side-accumulation of the nuclear chromatin,the fragmentation of the nuclear and the concentration of the cytochylema etc.Cell cycle detected by flow cytometry showed one visible apoptosis peak (20.6%) in front of the peak of G1.The typical ladder was found in the 15 g.L-1 agarose gel electrophoresis of the nucleus DNA.

透射电镜下可见细胞核染色质浓缩、边集、核碎裂及胞质浓缩等凋亡细胞典型的形态学改变；流式细胞术周期分析显示在G1期峰前存在一个凋亡峰（20.6％）；核琼脂糖凝胶（DNA 15 g.L-1）电泳呈梯状。

In other words, researchers have to prove that the disruption of this function, either genetically through mutation, or epigenetically through DNA methylation or chromatin modification, causes the initiation or progression of cancer.

换句话说，研究人员必须证明这些功能的中断，或者是通过遗传上的突变，或者是通过表观上的DNA甲基化或染色质修饰，导致癌症的发生以及进一步恶化。

For example, the transcription of mammalian α-globin gene is determined by the unique spatial arrangement of chromatin structure during erythroid differentiation.

举例来说，在红血球分化过程中α-globin的转录会受到染色体空间结构的调控。

Silenced chromatin, largely heterochromatic,contains a number of restrictive histone modifications, such as meH3K9, meH3K27, meH4K20,and histone deacetylation, which allow for a higher-order packing and inaccessibility to transcription factors.

沉默的染色质，大部分的是异染色质，包含大量的限制性的组蛋白修饰因子，例如meH3K9， meH3K27， meH4K20和组蛋白的脱乙酰作用，这些因子需要高度包装和不易转录因子。

Results Apoptotic cells were found among normal dentate hilus cells and CA1 cells. Chromatin condensation and clumping could be seen in the apoptotic nuclei. The shrinkage of the nucleus was shown by foldings and whorls of the nuclear membrane. At late stage of apoptosis, the nuclear membranes could be broken.

结果 电镜下，实验组大鼠海马齿状回门区和CA1区内可见散在的凋亡神经元，凋亡神经元主要表现为核周染色体的聚集和凝结成块，其核膜表现为皱缩和扭曲，在晚期凋亡的神经元有时可见核膜破裂。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐