查询词典 choroidal

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析，并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography，FFA)、吲哚青绿血管造影(indocyanine green angiography，ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例，73.5%)，双眼同时患病118例(80.8%)；后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%)；前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例，98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%)；后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障；毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现；炎症活动期FFA典型表现为斑驳状高荧光，ICGA发现脉络膜血管扩张、通透性增高等改变；VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎，随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

Research background: Choroidal neovascularization is a common cause of vision loss in patients, which often resulted from exudative Age-related macular degeneration、 pathologic myopia、 central serous chorioretinopathy、ocular histoplasmosis and angioid streaks, Rarely, CNV is seen in children, usually in association with inherited macular dystrophies. Despite extensive basic and clinical research, our knowledge of the complicated molecular mechanism of CNV is still limited, for these reasons currently used therapeutic approaches are insufficiently effective.

课题研究背景：脉络膜新生血管(choroidal neovascularization，CNV)是导致视力丧失的一种常见原因，多继发于渗出型年龄相关性黄斑变性、近视性黄斑变性、中心性浆液性脉络膜视网膜炎、眼组织胞浆菌病和眼底血管样条纹等眼病，在儿童罕见，主要与遗传性黄斑营养不良有关，尽管近年来进行了大量的基础和临床研究，但对CNV复杂分子机制的认识仍然非常有限，因此目前的治疗措施都不尽如人意。

The chief changes were the RPE and choriocapillaris atrophy in FFA and ICGA with the MPPE in quiescent phase, but the choroidal circulation anomalies disappeared including the choroidal filling delay and dilated.

静止期MPPE患者在FFA和ICGA中的荧光改变则主要为RPE和脉络膜毛细血管的萎缩，而脉络膜血管充盈迟缓和血管扩张等循环异常变化基本消失。

Main complications were expulsive choroidal hemorrhage, vitreous hemorrhage, low intraocular pressure, choroidal detachment, IOL askew and corneal edema after operation.

主要并发症有驱逐性脉络膜上腔出血、玻璃体积血、低眼压、脉络膜脱离、人工晶状体偏斜、角膜水肿等。

Because transient increases in choroidal thickness are followed by a prolonged decrease in synthesis of extracellular matrix molecules and a slowing of ocular elongation, and attempts to decouple the choroidal and scleral changes have largely failed, it seems that the thickening of the choroid may be mechanistically linked to the scleral synthesis of macromolecules, and thus may play an important role in the homeostatic control of eye growth, and, consequently, in the etiology of myopia and hyperopia.

由于细胞外基质分子合成持续减少以及眼轴变长减缓，脉络膜厚度瞬间增加，对脉络膜和巩膜变化的缓慢调节彻底失败，脉络膜增厚可能与巩膜合成大分子机械性联系在一起，因此它可能在眼生长稳态的控制方面发挥了重要作用，而且，也可能是近视和远视的病因。

Objective To study clinical results of transpupillary thermotheraphy for patients with polypoidal choroidal vasculopathy.

目的 察经瞳孔温热疗法(transpupillary thermotherapy， TTT)治疗息肉状脉络膜血科病变(phlypoidal choroidal vasculopathy)的临床疗效。

Fluorescein and indocyanine green fundus angiography were used to evalute the macular morphologic results. Results The result of fundus angiography showed that 90 cases 98 eyes had choroidal neovacularization, There were exudation age-related macular degeneration 39 cases (44 eyes), idophaic CNV 23 cases (23 eyes) and highly myopia 22 cases (25 eyes), Polypoidal Choroidal Vasculpathy 4cases (4eyes), multifocal choroidit 1 case (1 eye )and nodifferentiate 1 cases.

结果 90例98只眼黄斑部出血患者的眼底血管造影结果显示有脉络膜新生血管，其中老年黄斑变性湿性型39例44只眼，中心性渗出性脉络膜视网膜病变23例23只眼，高度近视22例25只眼，息肉状脉络膜血管病变4例4只眼，多灶性脉络膜炎1例1只眼，诊断不明1例。

In an attempt to evaluate the safety and efficacy of Healon in trabeculectomy, 20 eyes with Healon and 20 eyes without Healon injection after trabeculectomy are compared. Trabeculectomy using Healon will not induce transient rise of intraocular pressure. By filling the anterior chamber with Healon, a tamponing effect results which will maintain a deep chamber and reduce complications such as flat anterior chamber, choroidal detachment and striate keratopathy in the early postoperative period. In long-term evaluation there is no difference in pressure control, conjunctival scarring and corneal endothelial cell loss between Healon group and Non-Healon group.关键词 trabeculectomy , flat anterior chamber , choroidal detachment , intraocular pressure

为了评估Healen在小梁切除术中之疗效及安全性，选20位接受小梁切除术者，同时注射Healon於前房为实验对象，另20位接受传统小梁切除术为对照组，发现使用Healon并不会引起一过性眼压上升的现象，Healon注入前房，产生填塞作用，最大的好处是可以维持前房深度，减少术后合并症如前房消失，脉络膜剥离及角膜水肿等，然长期追踪，对於降眼压的幅度，不因使用Healon而可达到低眼压状态，也不会减少结合膜瘢痕化而促进房水引流，然Healon系一无毒，无炎性，无抗原性高黏稠性的物质，不因使用而发生炎性反应，同时有保护角膜内层细胞的功能。

Choroidal injury: contusions caused choroidal rupture, a small amount of bleeding in between the choroid and retina, Chenganhongse.

脉络膜损伤：挫伤致脉络膜血管破裂，少量出血可在脉络膜和视网膜之间，呈暗红色。

Objective To investigate the expression and signification of pigment epithelium-derived factor in choroidal neovascularization induced by krypton laser on Brown Norway rat.

目的探讨激光诱导BN大鼠脉络膜新生血管(choroidal neovascularization，CNV)中色素上皮衍生因子(pigment epithelium-derivedfactor，PEDF)的表达及意义。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。