查询词典 chemotherapy

YR-1 can attenuate the toxicity of immune function and bone marrow induced by chemotherapy drugs DDP and TAX in condition of unaffecting the efficacy, suggest YR-1 possesses the protective effect on the damage of immune function and bone marrow indued by chemotherapy drugs.

在不降低DDP和TAX疗效的情况下，YR-1对化疗药物所致荷瘤动物免疫功能的降低和骨髓抑制具有明显的拮抗作用，提示YR-1对化疗所致的免疫功能损伤和骨髓损伤具有保护作用。

Objective To observe the clinical effect in treating metastatic liver cancer in artery interventional and vein chemotherapy with oxaliplatin, 5-fluorouracil deoxyribonucleoside and citrovorum factor, mitomycin +lipiodol.Methods 38 non-operable cases of metastatic liver cancer were given transfemoral artery chemoembolization, catheterical head was placed into tumors feeding artery(common hepatic artery, left of right hepatic artery, hepatic segmental artery), veinous chemotherapy in the next day.

目的 观察奥沙利铂(Oxaliplatin， L-OHP)联合氟尿嘧啶脱氧核苷、亚叶酸钙、丝裂霉素+超液化碘油动脉介入+静脉化疗双通路对转移性肝癌的临床疗效方法不能手术的转移性肝癌38例，经皮股动脉穿刺插管至腹腔动脉，并超选至肿瘤的供血供氧血管后灌注化疗药并栓塞，于次日再给予静脉化疗。

Chemotherapy poisonous reaction: The chemotherapy causes the neutral granular cell reduces, the blood platelet to reduce, the hepatorenal function harm, disgusting vomitive.

化疗毒副反应：化疗导致的中性粒细胞减少、血小板减少、肝功能损害、恶心呕吐等两组之间比较均无统计学差异（ P 均＞0.05）；两组患者在化疗过程中均未出现心脏及肾脏的异常。

There were 15 pediatric ALL patients, which had received 50 times of chemotherapy with HD-MTX. The records about blood concentration of MTX and clinical conditions for 50 times chemotherapy were divided into two groups. Group I: contained 25 records of stand-risk patients, administering MTX 3.0g/m2; Group II: contained 25 records of mid and high-risk patients, administering 5.0g/m2. Continuous intravenous dripped MTX for 24th in both two groups, while implemented hydrating and alkalizing for 4 days. All patients were rescued 6 times through leucovorin, 15mg/m~2, since 12th after the end of MTX dripping. Then examined the blood concentration of MTX by fluorescence polarization immunoassay approach at 24h, 44h, 68h, at the same time inspected liver function, blood routine examination, the occurrence time and degree of toxicological reactions.

观察15例ALL住院患儿，接受大剂量MTX共50例次，按ALL危险度分2组，低危治疗组接受MTX剂量为3.0g/m2为I组；中高危治疗组接受MTX剂量为5.0g/m2为II组，连续静脉点滴MTX共24小时，同时给予水化碱化治疗，共4天，全部病例均在MTX滴注结束后12小时开始静脉推注四氢叶酸钙(leucovorin，LV)解救，15mg/m2/次，共6次，采用免疫偏振荧光法检测药物滴注24、44、68小时MTX血药浓度，同时检测两组病例的肝功、血常规，观察临床出现MTX毒副反应的时间及程度，观察每个病例毒副反应出现程度与MTX血药浓度关系，两组毒副反应程度比较，进行统计学分析。

Part-3 Tumor Suppressor Gene PTEN Up-regulates p53 Level and Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Objective: To investigate the effects and the mechanisms of tumor suppressor gene PTEN on level of p53 protein and sensitivity of HepG〓 cells to chemotherapy.

第三部分 PTEN在肝癌细胞中上调p53蛋白水平并增强化疗药物敏感性目的：研究抑癌基因PTEN对肝癌细胞化疗药物敏感性及p53蛋白水平的影响，并探讨相关机制。

Methods:The patients with breast cancer of stage Ⅲ were studied with randomized control assay and were divided two groups(preoperative chemotherapy group and non-preoperative chemotherapy group).

其局部复发率为10%~30%[1]，术前化疗对局部复发及远处转移的影响，1资料与方法1·1病例选择将1995年5月~2001年11月收治的乳腺癌患者随机分成两组，即术前化疗组、非术前化疗组，两组共136例，全部女性，年龄27~62岁。

The hematopoietic system was reconstituted and the chimaeras were formed.The results showed that hematopoietic stem cells coming from ES-D3 cells could reconstitute the mice following high dose chemotherapy in vivo. This research offers theories for HSCs induced from embryonic stem cells supporting the high dose chemotherapy of cancer.

将鉴定的造血干细胞移植入大剂量化疗的C57BL/6鼠，观察造血重建功能并证明有嵌合体形成，从体内实验方面证实了ES-D3细胞来源的造血干/祖细胞移植能够重建接受大剂量化疗小鼠的造血功能，为胚胎干细胞来源的造血干细胞支持大剂量化疗提供了实验依据。

However, the cytotox-ic dugs cant selectively kill the cancer cells without any side -effects, the decrease of peripheral blood WBC for myleosuppression caused by cytotoxic dugs contribute to the limitation of regular chemotherapy. Evidence was provided that cisplatin and cyclophosphamide used for ovarian cancer caused apoptosis in several in vivo tumors. For the reasons above, in our study, we detected the apoptosis of total peripheral blood WBC in patients with ovarian cancers before and after chemotherapy.

然而，由于化疗药物的非选择性组织杀伤引起的骨髓抑制而导致的末梢血白细胞减少，已经成为限制化疗剂量和按期进行规范性化疗的重要障碍，研究已证实卵巢癌的常规化疗方案中的顺铂及环磷酰胺能在多种肿瘤组织中诱导凋亡。

The toxicity occurent rate and toxic degree is slighter in treated groupthan in control group (p.05).Conclusion:"Huaier Granule" combined with chemotherapy is an effective method intreating patients with breast cancer. It can reduce toxic response of chemotherapy,enhance clinical efficacy and improve the quality of life.

槐耳颗粒对乳腺癌辅助化疗具有减毒增效作用，能改善全身症状，协同化疗、减轻化疗病人毒副作用，并能增强患者免疫功能，不失为乳腺癌治疗的有效方法之一。

objective this study was designed to investigate the chemotherapy effect and toxicity of co-chemotherapy with megadose tamoxifen in estrogen receptor positive human non-small cell lung carcinoma.

目的 进行大剂量的三苯氧胺 160 mg联合化疗对雌激素受体阳性的非小细胞肺癌患者的近期疗效分析和毒副作用的观察。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。