查询词典 chemotherapy

Methods 26 cases of cytologically and pathologically confirmed advanced breast cancer were treated with combined chemotherapy including paclitaxal and DDP the cardinal drug.

采用紫杉醇联合顺铂的联合方案，治疗晚期乳腺癌26例，初治患者10例，余16例均行根治术以后行辅助性放化疗后复发和转移的患者，其中有2例在复发转移后曾用过ADM、CTX、5-FU联合化疗。

Methods 26 cases of cytologically and pathologically confirmed advanced breast cancer were treated with combined chemotherapy including paclitaxal and DDP the cardinal drug. 10 out of 26 patients received no previous treatment.

采用紫杉醇联合顺铂的联合方案，治疗晚期乳腺癌26例，初治患者10例，余16例均行根治术以后行辅助性放化疗后复发和转移的患者，其中有2例在复发转移后曾用过ADM、CTX、5-FU联合化疗。

Objective To evaluate the effect of paclitaxel combined DDP on advanced breast cancer. Methods 26 cases of cytologically and pathologically confirmed advanced breast cancer were treated with combined chemotherapy including paclitaxal and DDP the cardinal drug. 10 out of 26 patients received no previous treatment.

目的 评价紫杉醇联合顺铂对晚期乳腺癌的治疗作用方法采用紫杉醇联合顺铂的联合方案，治疗晚期乳腺癌26例，初治患者10例，余16例均行根治术以后行辅助性放化疗后复发和转移的患者，其中有2例在复发转移后曾用过ADM、CTX、5-FU联合化疗。

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

Objective To verify the influence of cytotoxic chemotherapy to in situ apoptosis in acute leukemia.

目的观察细胞毒化疗对急性白血病原位细胞凋亡的影响。

Unlike standard chemotherapy,treatment with the molecular targeted anti-tumor agents is associated with an increased incidence of dermatological toxicities.

分子靶向抗癌药物的毒副作用迥然不同于传统的细胞毒药物，尤其是其最为常见的皮肤毒性，可引发身体和心理的明显异常，导致药物的减量或中断从而影响治疗的效果。

Surgical operation is the optimal treatment, radiotherapy and chemotherapy or endocrine therapy might be effect to desmoid tumor.

外科手术是主要的治疗方法，放疗、化疗和内分泌治疗可能对肿瘤有效。

Objective: to investigate the synergetic effect of disodium cantharidinate and vitamin B6 injection in combination with chemotherapy in the patients with advanced stage lung cancer.

目的：观察斑蝥酸钠维生素B6注射液对晚期肺癌患者化疗的协同治疗作用。

Elevated serum α FP was found before chemotherapy and dropped dramatical...

血清αFP可作为肿瘤标志物来诊断和监测病情。

During the treatment and in the followup duration, 8 eyes (8/13) had new tumors and recurrences. Finally, 2 eyes (2/13) were enucleated whil e 11 eyes (11/13) were saved in which 8 (8/11) recovered or remained good visual acuity. None of 9 patients had serious side effects of chemotherapy like leucoc ythemia, functional damage of liver and kidney, and dysacousia.

治疗期间及治疗后随访期间共有8只眼出现了肿瘤和肿瘤种植的复发和新发，经补充冷冻和TTT治疗后，最终2只眼（2/13）摘除，11只眼得以保留，其中8只眼恢复或保持较好有用视力。9例患者均未发生白血病、肝肾功能及听力损害等严重化学治疗毒性反应。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。