查询词典 chemotherapeutic

Methods A total of 36 patients with advanced renal cancer were definitely diagnosed by IVP, US, CT or MRI examination. A 5F Yashiro catheter was introduced into the femoral artery with Seldinger's technique under local anesthesia, abdominal aortagraphy and renal arteriography in both sides of kidneys were performed routinely to display the blood supplying arteries of tumor, thereafter, renal embolization was performed under superselective catherization for chemotherapeutic embolizing. Then the clinical effect was observed, the amount of blood loss and the operation time were recorded. All these results were compared with that of randomly selected 17 patients before surgical operation with advanced renal cancer admitted during the recent 3 years but without embolization.

36例中晚期肾癌患者，均经临床检查、静脉肾盂造影、B超、CT或MRI检查而确诊；采用Seldinger's技术，局部麻醉下经一侧股动脉穿刺插管，引入5F Yashiro导管，常规行腹主动脉及双肾动脉造影，以显示肿瘤的供血动脉，再将导管超选择插管或尽可能接近肿瘤病灶，进行化疗栓塞，观察其临床改善情况，计算术中失血量及手术时间，并与随机抽取我院近3年所做的17例术前未行肿瘤供血动脉栓塞的肾癌患者进行对照。

Low dose of Ad-PUMA significantly sensitized some cancer cells to chemotherapeutic ...

PUMA的作用与p53状态无关，是非常有前景的肿瘤基因治疗靶点。

Studies on this field will help idnetify valuable therapeutic targets for sensitizing cance cells to chemotherapeutic drugs.

在这一方向上的研究可为药物丌发提供潜在的靶点，从而提高肿瘤细胞对药物处理的敏感性。

Development of anti-HSV chemotherapeutic agents, such as acyclovir, substantiates the necessity for definitive detection as well as antiviral susceptibility testing.

另外，一些抗HSV的化学治疗药物，如acyclovir，也已证实有针对其进行抗病毒感受度之测试的必要性。

It is very significant for understanding the mechanism of C in reducing toxicity of alkylating chemotherapeutic drug and directing drug-using in tumor therapy.

这不仅有助于认识βC对烷化类化疗药物的保护作用机制，而且对指导临床化疗用药，减小药物不良反应具有十分重要的意义。

Theoretically, re-expression of tumor suppressor genes by demethylating agents may contribute to inhibiting the development of tumor. It has been suggested that DNA hypermethylation results in resistance to chemotherapy and consequently reduces the efficacy of chemotherapeutic treatment.

由于高度甲基化而暂停表达的抑癌基因，如果能应用去甲基化制剂逆转甲基化的异常状态，使之重获表达，理论上即可发挥其抑制肿瘤细胞生长的功能。

Result: With a high cancer-inhibiting rate on the animal model having been transplanted the cancer, this medicine can remarkably restrain the growth of cancer cells cultivated in vitro and improve the life quality of mouse model, and also shows obvious promotion and enhancement function on the DTH ear-swelling of mouse with cancer, the proliferation of mouse spleen lymphocyte induced by ConA and the cytokine (TNF-α、IFN-γ) of mouse with cancer respectively. It can obviously decrease the adverse effects like weight reduction, damage of viscera and degradation of life quality caused by the chemotherapeutic medicines, and has a remarkable stimulation on the lymphocyte proliferation induced by ConA. It is also able to improve the ratio of SMMC-7721 cells in G0-G1 period and reduce the cell amount in G2/M period to cut down the possibility of stepping into the division period; additionally, it can obviously inhibit some cancer genes of the cancer cells and meanwhile up regulate the cancer-inhibiting gene.

结果：本品能明显抑制体外培养肿瘤细胞的生长，对在体肿瘤移植模型动物具有较高的抑瘤率，能明显提高模型小鼠的生存质量；对荷瘤小鼠DTH耳肿胀、ConA诱导的小鼠脾淋巴细胞增殖、荷瘤小鼠细胞因子（TNF-α、IFN-γ）呈现明显的促进或提高作用；能显著减少化疗药所引起的小鼠体重降低、脏器损害以及生存质量下降等不良作用；本品含药血清对ConA诱导的淋巴细胞增殖具有明显的促进作用；能提高SMMC-7721细胞G0-G1期比例，降低G2/M期细胞数目，而减少其进入分裂期；对肿瘤细胞的多个癌基因具有明显的抑制作用，同时上调抑癌基因等。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。