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PIAS proteins play roles mainly through two mechanisms: acting as SUMO E3 ligases to promote modifications of some transcriptional factors and cofactors, especially sumoylation, and to regulate their transcriptional activation; acting as structural proteins to offer platforms for protein-protein interactions and to promote the abstraction and recruitment of other regulators in the cellular signal pathway complexes or gene transcriptional complexes, companied by the subnuclear location of target proteins.

PIAS蛋白的调控机制主要有两种：一种是通过其自身所具有的SUMO(small ubiquitin-related modifiers)E3连接酶活性，促进对一些转录因子、转录辅因子的化学修饰，尤其是SUMO化修饰，从而调控它们的转录活性；另一种是作为构架蛋白，为蛋白质之间的相互作用提供平台，促进细胞信号通路复合物或基因转录复合物中其它调节蛋白的去除和募集，并涉及到靶蛋白的亚核定位。

Asimprovement,the paper considers the influence of trim. Heel angle,trim angleand form stability lever are X,Y and Z axis so that three-dimensional curvecan be achieved which is shown as cellular figure picturesquely. It is called"stability interpolation area curve" in the paper.

本图谱较以往有所突破，计入了纵倾的影响使之参与平衡，在此基础上，以横倾角、纵倾角和形状稳性臂为三坐标轴绘出三维空间曲线，并以网格形象地展示出一空间曲面，称为"稳性插值曲面"。

On the basis of Movable Cellular Automata,the 2D numerical simulation of tungsten alloy armour piercer piercing armour target is done.

用可移动元胞自动机数值模拟方法，对钨合金(93W)穿甲弹侵彻装甲钢靶板进行二维数值模拟。

The piezoelectricity of commercially available PP cellular (EUH75 and SHD50) has been studied.

研究了两种商用聚丙烯蜂窝膜(EUH75和SHD5 0 )的压电性。

Therefore, how to improve cellular PP films\' thermal stability of piezoelectricity and charge storage becomes one of the focuses in the field of the functional dielectric materials.

因此，如何改善这种功能膜的储电及压电热稳定性是近年来倍受关注的课题。

Cellular analysis demonstrated that PIKA elicited the activation and proliferation of B cells and NK cells but not CD4+ and CD8+T cells.

细胞亚群分析的结果表明，PIKA可显著刺激B细胞和NK细胞活化、增殖。

RESULTS:After pinealectomized mice was irradiated WBI with 75 mGy X-rays,we found levels of plasma corticosterone increased obviously,and the effects of the proliferative reaction of splenocytes to ConA and spontaneous proliferation of thymocytes was found to be decrease. But injecting melatonin into pinealectomized mice or putting melatonin in the cultured cell,its immune functions might renew the enhancement.CONCLUSION:Melatonin of pineal gland might regulate the immunoenhancement induced by low dose radiation.MeSH Pineal body; Melatonin; Radiation; Corticosterone; Immunity,cellular

低剂量辐射(low dose radiation，LDR)全身照射(whole body irradiation，WBI)可引起免疫系统的兴奋效应，主要表现在以T淋巴细胞功能激活为主的细胞免疫和体液免疫功能的增强并可提高机体的抗瘤作用［4，5］，在LDR诱发免疫功能增强的同时伴有下丘脑-垂体-肾上腺皮质系统功能下调等神经内分泌功能的改变，神经内分泌对免疫系统的调节可能是LDR免疫兴奋效应发生的必要条件，松果腺MLT与辐射免疫兴奋效应的关系值得研究。

Results revealed that there are a lot of GnRHR positive cell in cytoplasm of pituitary body and ovary., The proportion of GnRHR positive cell is 31.5% in total cellular score of the adenohypophysis.

结果表明，在垂体和卵巢内都存在大量的GnRHR阳性细胞，阳性物质主要位于细胞质内。

When the plant was grown in a nutrient solution with 5 mmol /L of Ca, the cellular ultrastructure was damaged and plasmolysis was appeared.

不同处理下，各亚细胞组分中钙含量变化规律相似：细胞壁最高，胞质其次，而细胞器远低于前两者。5 mmol/L 钙处理对蜈蚣草羽叶细胞超微结构产生破坏，使细胞出现明显的质壁分离。

Long-term potentiation is an important form of synaptic plasticity and a cellular model for study of learning and memory.

长时程增强是突触传递功能可塑性的重要表现形式，是研究学习与记忆的细胞模型。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。