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ResultsMTT assay showed that various concentration of VM26 could effetely inhibit the growth cell; according to the results of flow cytometry, some typical sub diploid peaks were observed,the distribution of cell cycle phase changed at various time, the cell cycle of G2/M phase was arrested within 48 hours.

结果在一定浓度范围内，细胞的生长抑制率随着浓度的增加而增加，细胞的凋亡率随着时间的增加而增加，细胞周期被阻滞在G2/M期，在48小时达到高峰。

Results of the experimental groups: Comparison with the control groups, in 6h and 8h groups eminences of ependymal cells with cobblestone-like appearance were seen, their microvilli were further richer, and a number of microholes could be found on their base. In body part of SFO cell membrane of some ependymal cells were broken completely, their cytoplasm was no longer seen, and cell nucleus located at one side of the cell, 5-7μm in diameter and dividing lobe-like in shape. Beside those cells some ependymal cells appeared many folds on the top of surface. In 2h and 16h groups the observation results seemed no significant differences from the corresponding control groups.

实验组结果：与对照组相比，在6小时和8小时实验组中，可见成团的鹅卵石状室管细胞隆起于表面，微绒毛更为丰富，微绒毛根部可见到若干微细小孔，在SFO体部的一些室管膜细胞的胞膜完全破裂，胞质几乎荡然无存，仅剩胞核居于细胞的一侧，直径有5.7μm，呈分裂叶状；与这些细胞邻近的室管膜细胞表面最高处多呈现皱襞。2小时与16小时的实验组的观察结果与对照组相比未发现明显差异。

The effect of AA on BEL-7402 was not significant; However, AA could effectively enhance AT-induced hepatocarcinoma cell apoptosis and lesion severity through activation of caspase-3 but not ERKs-Conclusion; Caspase-3 and ERKs proteins could involve in arsenic-induced hepatocarcinoma cell apoptosis and differentiation respectively as intracellular signaling molecules; The effect between AT and AA on hepatocarcinoma is synergistic, which further inhibits cell growth and induces apoptosis in human hepatocarcinoma cells through activation of caspase-3 but not ERRs.

AA对BEL-7402无明显的作用，但能有效的通过caspase-3而不是ERKs的激活促进AT对肝癌细胞的凋亡效应。结论：ERKs和caspse-3信号蛋白可能分别参与了砷剂诱导的人肝癌细胞促分化和凋亡效应，AT和AA对肝癌细胞的作用有协同性，他们通过caaspase-3而不是ERKs的激活进一步抑制了肝癌的生长，诱导其凋亡。

Also, fiber serves as an excellent single-celled model for studying fundamental biological proc esses, such as cell elongation and differentiation Plant primary cell walls consist of mainly pectin, hemicellulose and cellulose, and are deposited during the cell expansion phase.

同时，棉纤维细胞也是研究细胞伸长、分化和细胞壁合成等重要生物学现象的理想系统。植物初生细胞壁主要由果胶、半纤维素和纤维素等多糖组成。

Cyclin-dependent kinases has effects on cell cycle by modulating function of eukaryon organism.The functions have been further studied in cell cycle and the process cell cycle,which will be beneficial to explain tumorigenesis pathomechanism and the new way of oncotherapy.

细胞周期素依赖性激酶是调节真核生物细胞周期的关键分子之一，深入研究细胞周期素依赖性激酶在细胞周期与细胞生长中的作用，对于阐述肿瘤发生、发展的病理机制以及肿瘤治疗的新途径具有重要的意义。

Ocean Rhodotorula is a single cell eukaryon biology, and cannot the movement, commonly the cell assume the cylinder, the ellipse or the circular generally, the cell long approximately 3-10um, wide approximately 15-5.5um, its shape and the size are raised the cultivate condition and the raise time will influence occur frequently the change, its colony is the pink.

海洋红酵母为单细胞真核生物，不能运动，细胞一般呈圆柱形、椭圆形或圆形，细胞长约3～10um，宽约15～5.5um ，其形态和大小受培养条件和培养时间的影响常常会发生改变，其菌落为粉红色。

D. N big mouse model was successfully made by adopting single side kidney cutting with induction, then by 24 week continuos observation on the change of various values of kidney and function, through testing of immunity florescence, electro-scope and optical scope, what we can see from model group is that typical kidney small cell got hardened by knot, and discarded, and dead, also small tube withered, small cell of on base film got thick, cell capsule wall was fibred, and base film got double layered.

实验研究采用单侧肾切除加以链脲佐菌素诱导，成功地复制出糖尿病肾病大鼠模型，对其肾脏结构和功能的改变各项指标，连续进行24周动态观察，并进行免疫荧光、电镜、光镜检测，结果表明：糖尿病肾病模型组可见典型的肾小球节段硬化、废弃、坏死，有大量蛋白管型，肾小球管糖元空泡沉积及脂肪滴，肾小管萎缩，肾小球基底膜明显增厚，球囊壁纤维化，基底膜双层化，有一例结核性肉芽组织及钙化等病理变化。

In a word, mad1 gene or mad1 combining with c-myc gene could inhibit TCCB cell proliferation but not normal fibrocytes in vitro and in vivo, which targeted hTERT, suppressed its transcription and expression, and down-regulated the expression of cyclin D1 and TGF-β1, to further block the cell cycle, change cell morphology and suppress proliferation.

综上所述，mad1基因或mad1联合c-myc基因能在体内外抑制TCCB细胞的增殖，但对正常成纤维细胞无明显影响，二者以hTERT为作用靶点，抑制其转录和表达，并下调cyclin D1和TGF-β1的表达，进而阻止细胞周期、改变细胞形态和抑制癌细胞的增殖。

The soft-diet feeding has no significant effect on proliferation of cell in cartilage. But, it leads to increased number of apoptotic cell in cartilage. It suggests that decreased masticatory force induced by soft-diet feeding promote the maturation and apoptosis of cell in cartilage.

软食喂养对这一时期大鼠髁突软骨中的细胞增殖活性影响不大，但却使细胞凋亡的数量增加，提示软食喂养可能加速了髁突软骨中细胞的分化、成熟、凋亡，进而影响髁突的正常发育。

Receptive field is the basic structural and functional unit for signal processing in visual system. X cell and Y cell are two main kinds of retinal ganglion cell.

感受野是视觉系统信息处理的基本结构和功能单元。X、Y细胞是两类主要的视网膜神经节细胞。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。