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The variation of red blood cell immunity function in the patients of type 2 diabetes mellitus (type 2 DM)(34 case) and diabetogenous nephropathy(31 case) was checked up in this article,undering the control with 40 case of healthy people.The results showed that the rate of floral hoop of red blood cell C3b receptor(RBC.C3bRR) and the red blood cell immunity elevated factor in the DN and type 2 DM patients dropped down remarkably.

本文检测34例非胰岛素依赖型糖尿病(2型DM)患者及31例糖尿病肾病患者的红细胞免疫功能，并与40例健康人进行对照，结果发现2型DM及DN患者红细胞C3b受体花环率(RBC.C3bRR)、红细胞免疫促进因子显著下降，红细胞免疫复合物花环率RBC。

Cell apoptosis is an important factor in the cell necrose following the skeletal muscle damage. The apoptosis relative genes such as Bcl-2, Bax are crucial in skeletal muscle cell spoptosis. Adaptation and damage are two dichotomal facets in daily physical exercise and military training.

细胞凋亡是骨骼肌损伤后细胞发生坏死过程中的重要作用因素，如凋亡相关基因：Bcl-2、Bax等在骨骼肌细胞凋亡过程中起着非常重要的作用。

Results: Tyroserleutide can significantly increase the life span of H22 tumor-bearing mice by 50-70% in dosages of 20ug/kg/d-80ug/kg/d,specially the high dosage of 80ug/ml can significantly increase the life span by 69.24%; Tyroserleutide can inhibit the growth of transplanted hepatocellular tumor BEL-7402 in nude mice,the rate of tumor inhibition was25-50% in dosages of 40-320ug/ml ,the inhibition rate of 160ng/ml was 44.03%; Tyroserleutide could inhibit the growth of H22 and BEL-7402 tumor in a dose-dependent manner. Simultaneously, tumoricidal activity of tyroserleutide against BEL-7402 cell line in vitro was observed hinger when compared with the control group(P.05).The inhibition effect of 72hrs was higher than 24hrs,48hrs,96hrs.And specially the high dosage of 160ug/ml can significantly inhibit growth of tumor cell by 19.36%. Tyroserleutide can activated PEM and marked enhance cytotoxicity andphagocytosis functions in vitro and in vivo. The OD values of cytotoxicity were observed hinger when compared with the control group(P.05).The cytotoxicity of macrophages activated by tyroserleutide against BEL-7402 and B16-F10 was 35.58%,61.2% in vitro and21.39%,47.63% in vivo. The cytotoxicity rate of nude mice PEM was 32.86%,73.07% in vivo. Furthermore, tyroserleutide alone could stimulated the production of IL-1B TNF- a and NO by M . Tyroserleutide and LPS could synergistically activated M producing more cytotoxicity effectors. Conclusion: Tyroserleutide had inhibition functions against hepatoma carcinoma .Its possible mechanisms were related to the affect that Tyroserleutide could inhibit tumor cell directively and induce tumor cells apoptosis or death effectively.

结果：酪丝亮肽能显著延长腹水型肝癌H_(22)小鼠的生存时间，给药剂量为80μg／kg／d时疗效最显著，达到69.24％，在20μg／kg／d-80μg／kg／d剂量范围内生命延长率为50-70％，给药剂量与荷瘤鼠生存时间呈现一定量效关系；酪丝亮肽能显著抑制人肝癌BEL-7402移植瘤裸鼠的肿瘤生长，给药剂量为160μg／kg／d时疗效最显著，抑制率为44.03％，并且在40-320μg／kg／d剂量范围内抑制率为25-50％，给药剂量与肿瘤抑制率呈现一定量效关系；酪丝亮肽体外对人肝癌BEL-7402细胞生长有一定的抑制作用，在作用72hrs时各浓度酪丝亮肽对肿瘤细胞的抑制作用较24hrs、48hrs、96hrs明显，其中浓度为100μg／ml时抑制率达19.36％；酪丝亮肽体内外均能增强小鼠腹腔巨噬细胞对肿瘤细胞的杀伤：体外作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与效应细胞对照组相比有显著性差异(P＜0.05)杀伤率分别达到35.58％、61.2％；体内作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P 。05)，杀伤率分别达到21.39%、47.63%；裸鼠腹腔巨噬细胞经酪丝亮肤作用后对BEL一7402、B 16一F10杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P.05)，最高杀伤率分别达到32.86%、73.07%；酪丝亮肤能增强单核巨噬细胞系统的吞噬功能，吞噬指数与生理盐水组比较有显著性差异(P.05)；酪丝亮肤体外作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与效应细胞对照组相比有显著性差异(P.05)；酪丝亮肤体内作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与生理盐水对照组相比有显著性差异(P.05)；酪丝亮肤能促进鼠巨噬细胞株R戌W264.7分泌合成IL一1p和NO，IL一1日、NO水平分别在酪丝亮肤作用24hrs、12hrs时达到高峰，酪丝亮肤单独应用能提高巨噬细胞的分泌合成功能，而且酪丝亮肤能与LPS协同作用刺激巨噬细胞的细胞毒效应分子分泌合成。

Generally, most of the follicles undergo atresia during their development in mammals, and only a few grow to maturation and ovulation. For many years, the mechanisms of follicular atresia have been one of the foci of study. Recently, with the development in studies on cell apoptosis, it has been proved that follicular atresia is a process of cell apoptosis. However, the endocrinological and molecular evens underlying follicular development and atresia and granulosa cell apoptosis in the goat has not been studied.

中文题名山羊卵泡发育、闭锁及其调控机理的研究副题名外文题名 Studies on follicular development and atresia and their regulatory mechanism in goat 论文作者于元松导师谭景和教授学科专业基础兽医学研究领域\研究方向动物胚胎学与胚胎生物工程学位级别博士学位授予单位东北农业大学学位授予日期2002 论文页码总数71页关键词山羊卵泡发育馆藏号BSLW /2003 /S827 /3 哺乳动物卵泡在发育过程中绝大多数闭锁退化，只有少数卵泡发育成熟至排卵。

General characteristics of cells, its chemical constituents ( protein, nucleic acid, carbohydrate, lipid), cell structure , cell cycle, cell division, four kinds of tissues (epithelial, connective, muscular, and nervous), organ, ten organ systems (dermal, skeletal, muscular, digestive, respiratory, circulatory, excretory, endosecretory, nervous, and reproductive).

细胞的一般特征，细胞的化学组成(蛋白质，核酸，糖类，脂类)，细胞的结构，细胞周期，细胞分裂(无丝分裂，有丝分裂，减数分裂)，四大组织(上皮组织，结缔组织，肌肉组织，神经组织)，器官，十大系统(皮肤系统、骨骼系统、肌肉系统、消化系统、呼吸系统、循环系统、排泄系统、内分泌系统、神经系统和生殖系统)。

Paraffin sectioning was employed to study the developmental structure of stems and leaves of Messerschinidia sibirica, especially the position, the structure and the formation and development of the salty gland. The result indicated: that salty gland of M. sibirica is from epidermic cell of stem and leaf. Based on the observation we found one primary kind of salty glands structure which consists of many cells on the epidermis including the collecting cell and the secretory cell and so on.

利用石蜡切片法研究了砂引草茎叶的解剖结构，尤其是对泌盐腺的位置、泌盐腺的形态结构及泌盐腺的发生发育过程进行了系统的研究，结果表明：砂引草的盐腺由茎叶的表皮细胞发育而成，通过观察发现在砂引草的表皮上存在着一种主要的盐腺结构，它是由多个细胞组成，包括收集细胞和分泌细胞等。

Results 6.3 mg/kg diazinon decreased the number of IgMplaque forming cell,blood serum erythrocytolysin level and DTH to SRBC.12.5,25 mg/kg dizainon could decrease the relative weight of thymus at about 20%,the number of IgMplaque forming cell at about 39% and 52%,the blood serum erythrocytolysin level at about 15% and 20%,the DTH to SRBC at about 33% and 35%,the ability of T lymphocyte proliferation at about 27% and 35%,the activity of NK cell at about 24% and 28%,respectively.

结果 敌匹硫磷染毒4周后，6.3 mg／kg组小鼠的体液免疫功能和迟发型变态反应受到抑制；12.5，25 mg/kg组小鼠的胸腺脏器系数均降低20％，抗体生成细胞数分别降低39%和52％，血清溶血素水平分别降低15％和20％，迟发型变态反应水平分别降低33％和35％，淋巴细胞增殖能力分别下降27％和35％，NK细胞活性分别下降24％和28％。

Observation under Transmission Electron Microscope was carried out and growth curve of E. coli was ploted out. It was indicated that PSPPs might change the permeability of cell membrane, make cell excrescent and inhibit cell division.

透射电镜观察和大肠杆菌生长曲线表明，该色素的抑菌作用可能是通过增强细胞膜的通透性，使细胞异常生长，抑制对数生长期的细胞分裂，使细胞质稀薄、细胞解体。

Signal 3 it is factor of APC excretive cell, the cell of antigen particularity T that makes activation divides melt into further the effect cell of different type.

信号3是APC分泌的细胞因子，促使活化的抗原特异性T细胞进一步分化为不同类型的效应细胞。

Mucous membrane protective screen is formed by the join between cell of alvine mucous membrane and cell, atrophy of cell of alvine mucous membrane, wither dies, cellular connective can send alvine path to connect flabbily appear a gender to increase, provide passageway; chemical protective screen for the bacterium inside bowel and toxin the digestive juice that shows epithelial excretive mucus and alvine memory are in bowel and digest enzymatic the chemistry that waits for material to reach its to develop.

黏膜屏障由肠黏膜细胞和细胞间的连接构成，肠黏膜细胞萎缩、凋亡、细胞连接的松弛可致肠道通透性增加，为肠内细菌及毒素提供通道；化学屏障指肠上皮细胞分泌的黏液及肠内存在的消化液和消化酶等物质及其发挥的化学功能。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。