查询词典 cathepsin

Some biochemical properties of cathepsin B, D, E, Hand L, calpain I and calpain II, dipeptidyl peptidase I, II, III and IV, and alanyl-, arginyl-, leucyl, and pyroglutamyl aminopep-tidases were introduced and their roles in meat texture were discussed.

分述了组织蛋白酶B， D， E， H 和L、肌钙蛋白I、II、二肽基肽酶 I， II， III ，IV、丙氨酰、精氨酰、亮氨酰及焦谷氨酰氨基肽酶以及它们在肉的质构中的作用。

Cathepsin D and β-tubulin marked with fluorescence were followed in distribution observed by laser scaning microscope, the distribution was from nucleus nearby to cytoplasm and apophysis, which suggested that they took part in traffic in cells.

荧光双标组织蛋白酶D及β-tubulin，共焦激光扫描显微镜下观察，可见二者伴随分布，均由开始的核周分布明显到散在分布于胞质及突起中，说明溶酶体与骨架蛋白密切相关，提示共同参与细胞内的运输。

OBJECTIVE: To determine the role of Asp98 in the catalysis of Cathepsin E.

目的：检验第98位天门冬氨酸残基的重要性。

Objective:To discuss cathepsin B expression in gastric carcinoma and its relationship with tumor invasion.

目的：探讨组织蛋白酶B在胃癌中的表达以及与胃癌浸润的关系。

These data suggest that cathepsin K plays a role in adipocyte differentiation.

提示cathepsin K在脂肪细胞分化过程中发挥作用。

RT-PCR and Western blot were used to detect the gene/protein expression of cathepsin K.

用不同浓度的cathepsin K抑制剂E-64进行干预，油红染色评估效果。

Expressions of cathepsin K mRNA and protein were upregulated during adipocyte differentiation.

在脂肪细胞分化的过程中cathepsin K mRNA和蛋白表达上升(P.05)。

Levels of cathepsin K were variable during adipocyte differentiation. Its depressor E-64 could inhibit the process.

结果 脂肪细胞分化前后cathepsin K的表达存在差异，其抑制剂可以阻止脂肪细胞分化。

Results:①The amount of human colon carcinoma cell line SW480 treated by quercetin decreased. The morphology of partial SW480 cells was shrunk volume, integrated cell membrane, condensed cytoplasm, pyknotic chromatin, nuclear fragmentation. Apoptotic Corpuscles were found by electron microscope.②MTT colorimetric assay showed quercetin inhibited the growth of human colon carcinoma cell line SW480 in a time- and dose-dependent manner when the concentration of quercetin was 30、60、90μmol/L.③Flow cytometry analysis showed the cell cycle of SW480 cell was restricted in G1/S. G0/G1 phase rate increased and S phase rate decreased with increasing concentration of quercetin and time lasting.④ Zymogram analysis assay showed the secretion of matrix metalloproteinases in human colon carcinoma cell line SW480 treated by quercetin decreased. With increasing concentration of quercetin, the secretion of MMP-2 and MMP-9 decreased.⑤Immunohistochemistry method demonstrated the position expression of Cathepsin-D in SW480 cell was suppressed by quercetin in a time- and dose-dependent manner.

研究结果：经槲皮素处理的人结肠癌SW480细胞数量减少，部分细胞体积缩小，细胞膜完整，胞浆浓缩，核染色质固缩，细胞核碎裂，形成凋亡小体；MTT法检测显示当作用浓度为30μmol/L~90μmol/L时，槲皮素对人结肠癌SW480细胞的生长有抑制作用，其抑制作用随着作用浓度的增加和作用时间的延长而增强；流式细胞学发现槲皮素主要作用于人结肠癌SW480细胞周期的G1/S期，大部分细胞被阻断于S期，随药物浓度的升高和作用时间的延长，G0/G1期细胞比例逐渐增加，S期细胞比例逐渐减少；酶谱分析法检测显示不同浓度的槲皮素能够抑制人结肠癌SW480细胞分泌MMP-2及MMP-9，随浓度的升高，MMP-2及MMP-9的分泌量减少；免疫组织化学法显示不同浓度的槲皮素处理人结肠癌SW480细胞后，Cathepsin-D的表达随药物浓度的升高和作用时间的延长而降低。

Objective To determine the distribution and influence of lysosomal neuraminidase, protective protein/cathepsin A and β-galactosidase in the inner ear of the mouse, and to observe their auditory alterations in enzyme deficiency.

目的：研究溶酶体神经氨酸酶(neuraminidase， Neul)、保护蛋白／组织蛋白酶A(protective protein/cathepsin A， PPCA)和β-半乳糖苷酶(β-galactosidase，β-gal)在小鼠内耳的分布及相互影响，观察各自酶缺乏时的听功能改变。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。