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TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e
治疗组在大鼠出现踝关节红肿后1周,炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节,另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg,20分钟后踝关节照光,激光波长627.sum,功率密度 100mwcm',照射时间1000秒,能量密度100)/。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径,治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后,治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗,随机治疗一侧膝关节,另一侧作自身对照。兔耳静脉注入I'arrainrelomg/Kg,20分钟后,膝关节用金蒸气激光照射,激光能量密度100)儿旷。24 /J'时后取膝关节滑膜作病理检查,并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果: 1。模型观察:CIA大鼠炎症高峰期滑膜下炎细胞浸润明显,滑膜细胞明显增殖,炎症达到高峰后二周,血管缀形成,并侵蚀和破坏软骨和骨, CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生,滑膜下炎细胞浸润,也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明,各组织对HMME 的吸收速度和吸收量不同,荧光值一时间曲线不同,滑膜组织比皮肤和软骨对 HMME的吸收多,在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明:PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性,但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好,统计学检验差异有显著性。。3_军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少,图像分析结果表明面密度(阳性染色的面积总和与统计视野面积的比值)治疗组小于对照组,统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多,图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组,统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小,与对照组相比,统计学检验差异有显著性。结论:二。CIA、AIA的病理改变类似人类RA,可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同,滑膜组织比皮。
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But since the opposition between the justice of God and our sins was such that no flesh by itself could or might have attained unto God, it behooved the Son of God to descend unto us and take himself a body of our body, flesh of our flesh, and bone of our bone, and so become the Mediator between God and man, giving power to as many as believe in him to be the sons of God; as he himself says, I ascend to my Father and to your Father, to my God and to your God.
&但由于两国之间的对立,正义的上帝与我们的罪过就是如此,无肉本身可以或可能已达到祂的神来说behooved上帝的儿子下降对待我们,并采取自己的一个机构,我们的身体,肉体我们的血肉和骨骼的骨我们的,所以成为之间的调停人与上帝赋予多达相信他成为神的儿子;正如他自己说:&我'升天我的父亲和你的父亲,以我的上帝和你的上帝。
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The results were as follows. In the insert mutation genotypes, there was significant difference between body weights of 2 weeks aged BB and AB genotype (P.05), while there was no significant difference between AA and other genotypes. In the mutation genotypes, there was no significant difference in body weight. Insert mutation loci had no significant effect on fossil bone length and shank length of 0-12 weeks aged chickens, only mutation loci had a significant effect on fossil bone length and shank length of 6 weeks aged chickens.
分析多态位点与0-12周龄鸡生长发育性状的关联性,结果表明:插入突变基因型中,2周龄鸡体重BB型与AB型差异显著(P.05),但AA型与AB型和BB型差异均不显著,而突变各基因型间没有显著差异;插入突变位点对0-12周龄鸡的龙骨长、胫骨长均没有显著影响,而突变位点仅在鸡6周龄时表现出与龙骨长、胫骨长间的差异显著性。
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The comparisons of biochemistry between OP and OR rats The differences between OP and OR rats included not only body weight, but lipids metabolism and insulin sensitivity as well, characterized with insulin resistance, increasing in serum free fatty acids and ketone body, and hepatic TC and TG in OP rats. However, no significant differences were observed in serum TG, TC, LDL, HDL and fasting glucose between OP and OR rats.⑶Comparisons of metabolites in serum, urine and liver tissue between OP and OR rats①There were significant differences in amino acids concentration between OP and OR rats,especially in liver tissue, such as high concentrations in ketogenic and glucogenic amino acids in OP rats, suggesting differences in amino acids metabolism;② The different metabolites between OP and OR rats included increasing of various saturated fatty acids and decreasing of polyunsaturated fatty acids in OP rats;③The urinary metabolites analysis indicated that different structure or metabolism of gut microflora might exist between the two phenotypes, which probably influenced the regulation of body weight gain;④The end-products of catecholamines in urine and intermediates of krebs cycle in serum in OP rats were all up-regulated, suggesting that the activity of sympatheic nervous system and energy metabolism was higher in OP rats than OR rats.
胰岛素耐受实验和胰岛素敏感指数表明OP动物的胰岛素敏感性较OR动物下降,而OP大鼠血清中游离脂肪酸、酮体、肝脏总胆固醇和甘油三酯水平显著升高;但是,OP与OR大鼠血清中总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白和空腹血糖等的水平并无显著性差异;⑶肥胖易感与肥胖抵抗大鼠血清、尿液和肝脏组织提取物中代谢物的比较研究表明:①OP与OR大鼠的血清、尿液和肝组织提取物中多种氨基酸的含量存在显著差异,并以肝组织中的差异氨基酸数量为最多,包括各种生酮和生糖氨基酸水平在OP组的升高,说明氨基酸代谢的差异是两种体重表型大鼠之间存在的重要差异特征之一;②OP与OR动物肝脏和血清差异代谢物中包含多种饱和长链脂肪酸的升高如十四烷酸、十六烷酸、硬脂酸等和多不饱和脂肪酸的下降如亚油酸和花生四烯酸,说明两种体重表型动物的肝脏脂肪酸代谢存在明显差异;③长期高脂饮食喂养后,动物的尿液代谢物分析表明OP与OR动物体内的肠道菌群结构存在差异,这些菌群上的差别可能在动物体重增长的调节上产生影响;④与OR动物相比,OP动物尿液代谢物中儿茶酚胺类递质的代谢终产物如高香草酸、扁桃酸和4-羟基苯乙酸明显升高。
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Under the condition of the slide between pile and soil around pile is taked into account,five equations are established, including the equation of compatibility between the settlement of pile cap soil and the settlement of pile cap; the equation of compatibility between the settlement of pile head soil and the settlement of pile head; the physical equation between the settlement of soil around pile shaft and the settlement of pile shaft;the equation of equilibrium between loads on the pile cap, side frictional stress and restraints of pile head; the equation of compatibility between the deformation of the pile body and the subtraction between the settlement of pile cap and the settlement of pile heap.
桩身单元和土单元存在着相互作用,在允许桩土相对滑移的前提下,建立桩顶土体沉降与桩顶沉降的协调方程、桩底土体沉降与桩端沉降的协调方程、桩土相对位移与桩侧摩阻力的物理方程、桩身力的平衡方程、桩身压缩和桩顶沉降与桩端沉降之差的协调方程。
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To achieve these goals, the following actions must be taken.First,the vertical and horizontal connection of city planning must be strengthened;balance be made between market system and local governments in allocating materials;cooperating systems between city governments be intensified;in order to guarantee the balance between internal structures of urban systems.Second,the stability of agricultural production and provisionment must be guaranteed;rural integration be accelerated;system of land transfer be reformed;rural citizens be given equal status in participating urban development and sharing the fruit of urban development;in order to guarantee the balance between rural and urban development.Third,supervision of upper governments must be strengthened;the "personal rationality" of local governments(the choice of short-term benefits for local area) be restrained and local governments be stimulated to bring into play "collective rationality"; scientific development patterns in active improvement of urban quality and steady enlargement of urban size be insisted;in order to guarantee the balance between urban and economic development,and the balance between improvement of urban quality and enlargement of urban size.Last but not the least,considering the crucial status of urban social development in deciding the socialist direction of urbanization of our country,it\'s essential that social development be made a political responsibility of local governments in order to guarantee the balance between the social and economic development of cities.
为此,应当加强城市规划的纵向与横向衔接,平衡市场机制与地方政府这两只手的资源配置功能,强化地方政府问的合作机制,确保城市体系内在结构的均衡;保证农业生产稳定与粮食供应,加快农村整合,改革土地流转制度,确立农民参与城镇发展的平等地位,合理分享城镇发展成果,实施拖腿扩门并举战略,确保农村发展与城镇发展的均衡;加强上级政府监管,抑制各级地方政府的&个人理性&,促使其更多地发挥出&集体理性&,坚持积极提升城市质量、稳妥扩张城市规模的科学发展模式,确保城市发展与经济发展、城市质量提升与规模扩张的均衡;城市社会发展事关我国城镇化的社会主义方向,要把社会发展作为地方政府无可旁贷的政治责任,才能确保城市社会发展与经济发展的均衡。
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Study 2 used 2(conflict target: supervisor/subordinate)×3(conflict management mode: integrating/obliging/dominating ) design, letting participants to evaluate the effeciency and appropriateness of the management mode used in the contexts. The results showed:(1) the integrating mode were perceived most efficient and appropriage within the three conflict modes;(2) the interaction between the referent role of conflict object and the management mode is significant, which means when the conflict took place with the supervisor, the participants thought the obliging mode was more appropriate and efficient , while when it took place between the subordinate, they thought the dominating mode was more appropriate and efficient than obliging mode.(3)the interaction between SDO and conflict management mode is significant, which means the participants with high SDO would make no preference between obliging and dominating mode, but the participates with low SDO would favor the dominating rather than obliging mode;(4) the interaction between dialectical ways of thinking and conflict management mode is significant, the lower the level of dialectical way of thinking the participants were, the more difference were found between the appraisal of obliging and dominating mode.(5) the moderating effect of SDO and dialectical ways of thinking to the relationship between conflict object and management mode were not significant, which means the relative position of conflict object in China is so strong that can't be affected by SDO and dialectical ways of thinking.
研究二采用2*3(冲突处理方式:迁就/支配/整合)的情境设计,让被试对情境中冲突主角的冲突处理方式进行恰当有效性的评价,结果显示: 1、在与上级或下级发生冲突时,被试对迁就、支配和整合三种策略中整合式的恰当有效性的评价最高;2、冲突对象的相对地位与冲突处理方式之间的交互作用显著,即当与上级发生冲突时,被试认为使用迁就的处理方式比支配的方式更恰当有效,而与下级发生冲突时,被试则认为使用支配的处理方式比迁就的方式更有效; 3、SDO与冲突处理方式之间的交互作用显著,即SDO水平高的被试对迁就式与支配式的认知评价没有差异,而SDO水平低的被试对支配式比迁就式有更高的评价;4、辩证思维水平与冲突处理方式之间的交互作用显著,即低辩证思维水平的个体比高辩证的个体对支配式与迁就式的评价差异更大;5、SDO水平及辩证思维方式水平对冲突对象影响冲突处理方式评价的程度的调节作用不显著。
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The results show that the brush-plating coating is even and compact from section plane with good toughness and adhesion. The microhardness of the coating is 230.6HV0.5 which is 3 times of cast aluminium substrate. The wear resistance of the coating is 3 times of cast aluminium substrate. But the friction coefficient of the coating is 0.70 which is more high than that of the substrate, which is favorable for the fixed conjugate between the axis sheath and the axis seat of the gear-box.
结果表明,镀层厚度分布均匀、致密,镀层与基体界面清晰,未出现氧化物夹层,镀层的韧性和结合强度均较好;测得碱性铜及铸铝基体的显微硬度分别为230.6、74.2HV0.5;碱性铜的镀制使基体表面显微硬度及耐磨性均提高了2倍多,磨损状况明显改善。
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Chan and Curran believe the differences between the all-Scottish cast and the local cast help distinguish this new production.
Chan 和 Curran 相信全苏格兰演员和本地演员两个不同班底演出的分别会有利於认识新剧。
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In this paper the as-cast microstructure, the rules of phase precipitation, the change of microstructure and minor phase content and the degeneration of aluminide coating after thermal exposure at temperature range from 850℃ to 1100℃ for 1000-3000 hours have been studied in comparison between two kinds of low chromium-high tungsten cast nickel-base superalloys.
本文对比地研究了两种低铬-高钨系列的铸造镍基高温合金的铸态显微组织,在850~1100℃范围内热暴露1000~3000小时后的相析出规律,显微组织和微量相的变化及铝化物涂层的蜕化。
- 相关中文对照歌词
- Bone Bone Bone
- It's A Bone Thang
- The Originators
- The Bone
- Bump In The Trunk
- T-Bone
- I'm Gonna Move Among You
- Hillbilly Bone
- Rebirth
- Given The Dog A Bone
- 推荐网络例句
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Putt your way through 36 fun-filled holes of minigolf on 3D designed courses with elevated greens, bunkers, bridges and water hazards, among other crazy obstacles.
您的推杆方式,通过36个有趣的填孔迷你的三维设计的课程,以提升绿党,掩体,桥梁和水的危害,除其他疯狂的障碍。
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Some participles can be used either as attributes or as predicatives.
有些分词既可当定语用,也可当表语用。
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Over time, the jaw crusher has been a significant improvement, it is a highly efficient, energy-efficient equipment often broken.
随着时间的推移,颚式破碎机得到很大的改进,已经是一种高效,节能的常用破碎设备。