查询词典 capsaicin

To increase the isolation efficiency of capsaicin,the optimum technics of isolation and identification of capsaicin was studied.

为了提高辣椒素的提取效率，对辣椒素提取条件进行了优化研究。

Meanwhile, the stimulatory effect of the same dose of capsaicin on all the afferents was markedly enhanced.

同时，相同剂量Capsaicin刺激C-纤维的放电，却大量增加。

In the present study, weclarify the capsaicin concentration dependency for developmentand maintenance of secondary mechanical allodynia and the roleof spinal opioid receptor like1 (ORL1) receptor and N -methyl-d-aspartatereceptor in the development and maintenance of secondary mechanicalallodynia induced by an intradermal capsaicin injection. Capsaicin50 L of 0.03% induced the most intense secondary mechanicalallodynia.

在这个实验中，作者研究皮内注射辣椒素与继发性机械性异常性疼痛的相关性和脊髓阿片受体相关1受体激动剂（ ORL1）和 N-甲基-D-天门冬氨酸受体在皮内注射引起的继发性机械性异常性疼痛的发生和维持中的作用。0.03%的辣椒素50uL 导致最强的异常性疼痛。

Our project adopts capsaicin as the antifouling agent to produce fishing net and antifouling coatings. It has the following advantages:The capsaicin has the good ability to lustrate marine mollusk.

该项目以辣椒素为防污剂，生产的网具防腐剂污涂料，具有以下特点：1、辣椒素有很好的防污性能；2。

Objective To investigate the modulatory effects of substance P on capsaicin-activated current and the pain pathway mediated by capsaicin.

目的 研究P物质对急性分离的大鼠三叉神经节神经元辣椒素受体亚型1(VR1)的调制作用，探讨SP对辣椒素在疼痛传导中作用的影响。

The results obtained are as follows:(1) intrarenal artery injection of capsaicin (20, 40, and 60 nmol/kg) increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2) pretreatment with ruthenium red (40 mmol/kg), a capsaicin receptor antagonist, completely abolished the effect of capsaicin; and (3) pretreatment with a nitric oxide synthase inhibitor L-NAME ( N6-nitro-L-arginine methylester, 0.1 mmol/kg), significantly enhanced the ARNA response to capsaicin.

结果表明：(1)肾动脉内注射辣椒素20、40和60nmol/kg可呈剂量依赖性地兴奋肾传入纤维的活动，而动脉血压不变；(2)静脉内预先应用辣椒素受体阻断剂钌红(40 mmok/kg)，可完全阻断辣椒素对肾传入纤维的兴奋作用。(3)静脉内预先注射一氧化氮合酶抑制剂L-NAME(0.1 mmok/kg)，能延长并增强肾传入神经对辣椒素的反应。

The six kinds of nanoparticles water dispersion were as follows:rotenone/carboxymethyl chitosan-grafted-ricinoleic acid(Rot/CMC-g-RA), azadirachtin/carboxymethyl chitosan-grafted-ricinoleic acid(Aza/CMC-g-RA),capsaicin/ carboxymethyl chitosan-grafted-ricinoleic acid(Cap/CMC-g-RA),rotenone/ricinoleic acid sodium,capsaicin/ricinoleic acid sodium,azadirachtin/ricinoleic acid sodium.

分别为：鱼藤酮/羧甲基壳聚糖接技蓖麻油酸共聚物(Rot/CMC-g-RA)、辣椒碱/羧甲基壳聚糖接技蓖麻油酸共聚物(Cap/CMC-g-RA)和印楝素/羧甲基壳聚糖接技蓖麻油酸共聚物(Aza/CMC-g-RA)纳米粒子水分散制剂，以及鱼藤酮/蓖麻油酸钠、辣椒碱/蓖麻油酸钠和印楝素/蓖麻油酸钠纳米粒子水分散微乳液。

In order to further investigate the relationship of SP and ESCs, we design two level experiments —in vitro and in vivo. In vivo, firstly, We establish the nomal rat full-thickness wounds model, and employ integrin β1 keratin 19(K19)、 keratin 15(K15)、 Brdu as ESCs markers to conform the existence of ESCs in the granulation tissue of Group Capsaicin (rats were subcutaneously injected capsaicin pre-injury to damage sensory neuron and block the secretion of neuropeptides), Group Control, and Group SP (rats were injected SP in the wound postinjury). Secondly, as diabetic skin lacking of SP due to extensive pathological changes of sensory ending, we make a hypothesis:one of the main reason of unhealing wounds on diabetic patients could be insufficient SP which lead to fewer ESCs recruitment around wounds.

在此基础上，为进一步验证P物质促进表皮干细胞向肉芽组织中募集这一重要发现，本研究首先利用β1整合素、K19、K15等干细胞标记物以及干细胞慢周期性的特点，分别在体观察了正常皮肤伤口愈合过程中SP组、辣椒素组采用特异性感觉神经毒性药物辣椒素(capsaicin皮下预注射化学性除去感觉神经从而阻止神经肽分泌、对照组肉芽组织中表皮干细胞分布特点；其次，糖尿病患者皮肤存在周围末梢神经的损伤和神经肽含量的下降，这是否会导致糖尿病皮肤伤口创缘表皮干细胞募集不足，继发伤口难愈？

Unilateral perineural application of 3% capsaicin selectively affects afferent C-fibers, and results in reduction of SP-and CGRP-IR and increase of NADPH diaphorase activity in ipsilateral superficial laminae of dorsal horn; Also, the application of Cap results in significant decrease in GABA-IR neuroprofile and increase in expression of cfos in many neurons the same area; Ruthenium red, as a functional antagonist of capsaicin, can completely prevent capsaicin-induced depletion of SP-and GABA-IR; Capsaicin-induced GABA-IR reduction can be partially blocked by pretreatment with a NK-1 receptor antagonist spantide and a NMDA receptor antagonist APV to the spinal dorsal horn.

辣椒素急性施加于外周神经可选择性影响C类传入纤维，引起末梢终止区域内SP-和CGRP-IR的减少，NO合成酶活力增加；同时也引起此区域内GABA-IR的减弱，GABA-IR神经元数目的减少以及背角浅层C-fos的大量表达；Cap的功能拮抗剂能完全翻转Cap所致的SP和GABA-IR的减少；应用NK-1受体和NMDA受体拮抗剂均可部分阻断Cap引起的GABA-IR的减少。

The results obtained are as follows.(1) Following microinjection of capsaicin (10μmol/L, 50nl) into the AP, MAP, HR and RSNA were significantly increased from l2.34±0.53 kPa,328.52±7.54 bpm and 100±0% to 15.17±0.25kPa (P.001), 354.81±8.54bpm (P.001) and 156.95±7.57%(P.001), respectively.(2) Ruthenium red (RR, 100mmol/L, 0.2ml, iv), a capsaicin receptor antagonist, significantly inhibited these effects of capsaicin.(3) Pretreatment with a NMDA receptor antagonist MK-801 (500μg/kg, 0.2ml, iv) also reduced these effects of capsaicin.

实验结果如下：(1)最后区内注射辣椒素可引起MAP、HR和RSNA明显增加，分别由12.34±0.53kPa、328.52±7.54bpm和100±0％增至15.17±0.25kPa（P＜0.001）、354.81±8.54bpm(P.001)和156.95±7.57%(P.001)；(2)静脉注射辣椒素受体阻断剂钌红(100mmol/L， 0.2ml)后，辣椒素的上述效应可被明显抑制；(3)预先应用NMDA受体阻断剂MK-801(500μg/kg， 0.2ml， iv)也明显抑制辣椒素的兴奋效应。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。