查询词典 cancer

Cancer Genetics and Cytogenetics offers in-depth coverage of the cellular and molecular aspects of cancer research.

癌基因和细胞遗传学杂志深入研究了癌症的细胞和分子方面。

In contrast, cancer cells lacking functional P53 would be expected to be sensitive to viral replication and subsequent cytolysis. However P53 defections wildly exist in most of human cancer cell, deletion of E1B-55kD gene can make the adenovirus target at p53 mutation tumor cell.

以往的研究表明，大部分人类肿瘤中均存在p53基因突变，因此E1B55kD蛋白缺失的重组病毒只能在P53功能异常的肿瘤细胞中复制，而在正常细胞中该重组病毒由于缺乏对抗P53蛋白的病毒产物，不能有效复制，因此具有肿瘤靶向治疗的特点。

Methods: The telomerase activity in breast cancer cells and MRC-5 cell line were detected semi-quantitively by TRAP-ELISA assay. Virus proliferation as- say and cell viability assay were used to evaluate the proliferation and cytolysis selectivity of CNHK300, and the results were compared with those of wtAd5. The breast cancer cells were treated with CNHK300 combining paclitaxel to evaluate the killing effect of the combined regimen.

用TRAP-ELISA方法检测乳腺癌细胞株(MDA-MB-453、SK-BR-3)和正常成纤维细胞株MRC-5的端粒酶活性；进行病毒增殖实验和细胞生长抑制实验，并与野生型腺病毒wtAd5进行对比，验证CNHK300选择性复制和选择性杀伤能力；用细胞生长抑制实验进一步考察CNHK300与化疗药物紫杉醇联合应用对乳腺癌细胞的杀伤作用；用Western blot检测腺病毒E1A在细胞中的表达。

Because different cell lines may show various levels of susceptibility to adenovirus infection and virus production, non-selectively replicating wtAd5 was used to be a comparison with the tested conditionally replicating adenovirus CNHK500.ONYX-015, the first replication-competent adenovirus entered into clinical trials was also used to be a comparison. We used virus proliferation assay, cell viability assay and western blot to evaluate the proliferation and cytolysis selectivity of CNHK500. Results demonstrated that the CNHK500 virus proliferation multiples in breast cancer cell lines after 48 hours is similar to that of wtAd5, ONYX-015 virus proliferation ability is less than that of CNHK500 in cancer cells.

然后，通过与ONYX-015（E1B 55 KD a蛋白缺失的2型和5型嵌和型腺病毒，美国ONYX生化制药公司研制）、wtAd5进行对比，利用病毒增殖实验和细胞生长抑制实验，验证了CNHK500选择性增殖能力和肿瘤特异性杀伤作用；利用Western Blot检测CNHK500腺病毒E1A和E1B在乳腺癌细胞和正常成纤维细胞中的表达差异，揭示了腺病毒肿瘤靶向性的机制；利用携带绿色荧光蛋白的CNHK500-EGFP感染乳腺癌细胞株和正常成纤维细胞株，直观地观察其感染乳腺癌细胞的能力和在乳腺癌细胞中的增殖过程。

"Most chemotherapeutic approaches to cancer try to target cancer cells specifically and do something that slows or stops their cell growth process," Dashwood said.

"大多数针对癌症的化疗方法，是试图以特定的癌细胞为靶标，减缓或停止癌细胞的生长过程，"Dashwood说。

We can use CT scan and GC system to establish the correlation between lung cancer patient and the marker VOCs in their exhaled breath. Detecting Benzene,Propyl benzene and Decane helps making diagnosis of lung cancer.

临床上应用颇成熟的CT检查对肺癌的检出其敏感性和特异性都较高，笔者通过CT检查和气相色谱系统的联用，探讨肺癌与肺癌患者呼吸气体中的特征性有机成分的对应关系。

Methods The MIN in 50 cases of laryngeal cancer were detected by the methods of PCR denature PAGE polymorphous markers BAT 26 and BAT 40. Results Twenty six percent of patients with laryngeal cancer had MIN.

采用 PCR-变性聚丙烯酰胺凝胶电泳等分子生物学方法用微卫星多态标记物 bat - 2 6和 bat - 4 0检测 5 0例喉鳞癌组织的 MIN。

To determent whether cyclin E is an independent prognostic factor for breast cancer, we completed a meta-analysis of the published literature. Methods:All data that were associated with the study of the relationship between cyclin E and the prognosis for breast cancer was pooled from PubMed and CBMdisc database.

检索PubMed以及CBMDisc数据库中研究cyclin E表达与乳腺癌预后关系的文献，使用meta分析的方法分析cyclin E是否为乳腺癌的预后因素。

Our findings indicate that levels of Dicer and Drosha mRNA in ovarian-cancer cells have associations with outcomes in patients with ovarian cancer.

我们的研究发现提示卵巢癌细胞中Dicer和 Drosha酶的mRNA水平与卵巢癌患者预后有关。

The top three kinds of maligancy were digestant cancer, hematal cancer and lung carcinoma.The systolic blood pressure,HOMA-IR, plasma insulin and triglyceride were increased.

消化道肿瘤、血液系统肿瘤、肺癌占据前3位，收缩血压、HOMA-IR、血浆胰岛素、甘油三脂等水平升高。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷