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The purpose of this study is to discuss the application of photodynamics in different aspects including photodynamic diagnosis of CA,the function of Langerhans cell in local immunity around PDT and PDT for cervical CA.

本研究从光动力诊断应用于CA、PDT治疗前后对局部朗格汉斯细胞免疫功能的影响及将PDT应用于宫颈CA的临床治疗等不同方面进行研究,旨在更好地将光动力学应用于临床实践。

This thesis gives the introduction of the construction technique of a Slab Non-ballast Track, which has been used in the Shuanghe Bridge of Qin-shen Passenger Railway, and sheds light on a series of key construction techniques, mainly including: fabrication of the trackslab, research and production of CA sand mortar, construction of concrete bearing and convex retaining wall, paving of track slab, pouring of CA mortar mixture, construction of the filled cushion slab etc. All these will have the significant reference and application value for its employment to the construction of the city overhead to rack and the express railway.

论文介绍并总结了在秦沈客运专线双何特大桥采用的无碴轨道的一系列关键施工技术,主要包括轨道板的制造工艺、CA砂浆的研究及配制、混凝土底座及凸形挡台施工、轨道板铺设、CA砂浆灌注、充填式垫板的施工等技术,对城市高架轻轨、高速铁路桥梁等工程,此项新技术的推广具有重要参考价值和实用价值。

When cells were illuminated Ca〓 exfluxed from mitochondria to cytoplasm (Roux et al 1981). Therefore, Ca〓 may be an active factor in the regulation of green cell metabolism under the condition of illumination.

照光时Ca〓从线粒体向细胞质排出(Roux et al 1981),因此Ca〓在调节照光时绿色细胞的代谢中可能起重要作用。

The seeds of rice mutants with Ac/Ds elements inserted from rice variety Dongjin were selected and the callus were induced from scutellum of mature embryo. Ca(superscript 2+) with different concn. was added into the selected optimum enrichment, differentiation and rooting medium to study the effect of Ca(superscript 2+) on proliferation, differentiation and rooting of rice callus.

方法]选用水稻品种Dongjin的Ac/Ds插入突变株系的种子,从成熟胚盾片诱导出愈伤组织,在筛选出的最适增殖、分化及生根培养基中添加不同浓度的Ca(上标 2+),研究Ca(上标 2+)对水稻愈伤组织增殖、分化及生根的影响。

The better condition synthesizing the assorted minerals of zirconolite and sphene doping neodymium is holding 30 min at 1230℃, and the better formula is nCa(subscript 1-x/2-y/4 Zr(subscript 1-y/4);Al(subscript x/2) Ti(subscript 2-x/2O7): nCa(subscript 1-x NdAl Ti(subscript 1-x)SiO5[4/(4-y)]:1. Nd(superscript 3+) can enter crystal lattices of ite and sphene. Sphene can immobilize Zr(subscript 4+), Al(subscript 3+) and Nd(subscript 3+); Zr(subscript 4+) and Nd(subscript 3+) replace Ca(subscript 2+), and Al(subscript 3+) replaces Ti(subscript 4+). Zirconolite can immobilize Al(subscript 3+) and Nd(subscript 3+) Nd(subscript 3+) replaces Ca(subscript 2+) and Zr(subscript 4+), and Al(subscript 3+) and replaces Ti(subscript 4+).

研究表明:钙钛锆石和榍石组合矿物固化体较佳的合成条件是在1230℃条件下保温30min,较佳配方的摩尔比为nCa(下标 1-x/2-y/4 Nd(下标 x+y/2)Zr(下标 1-y/4)Al(下标 x/2)Ti(下标 2-x/2) O7:nCa(下标 1-x Nd Ti(下标 1-x)-SiO5=[4/(4-y)]:1;Nd(上标 3+)能够进入钙钛锆石和榍石晶格,榍石能够固溶Zr(上标 4+)、Al(上标 3+)、Nd(上标 3+),Zr(上标 4+)和Nd(上标 3+)取代Ca(上标 2+)位,Al(上标 3+)占据Ti(上标 4+)位,钙钛锆石能够固溶Al(上标 3+)、Nd(上标 3+),Nd(上标 3+)进入Ca(上标 2+)位和Zr(上标 3+)位,Al(上标 3+)占据Ti(上标 4+)位。

The results indicate seawater concentration has no effect on absorbency, pH, relative density, dry matter and water contents in Aloe vera leaves. While, seawater stress causes increased MDA and membrane penetration, decreased phytochroms, prolines and NO_3~--N. It is beneficial to plant growth when irrigation was done with 10% seawater, because of higher ratio of K~+/Na~+ and lower ratio of Na~+/Ca~(2+). In addition, the polysaccharide contents in Aloe vera leaves increase twice and triplication under 25% and 50% seawater irrigation respectively, the barbaloin contents increase over triplication in var. 75% seawater and over twice in var. 50% seawater and var. 100% seawater. However, when seawater concentration exceeds 25% the growth of plant was inhibited, biomass decreased, flowering time was deferred, Ca~(2+) content decreased caused by Na~+ accumulation in leaves.

结果表明:在海水胁迫下,库拉索芦荟全叶汁的吸光度、酸度、相对密度、总固形物和水分含量总体上受海水浓度的影响不大;但芦荟叶的丙二醛含量和质膜透性增加,叶绿体色素、脯氨酸和硝态氮含量减少;在10%海水浇灌下,芦荟叶细胞具有较高的K~+/Na~+比和较低的Na~+/Ca~(2+)比,对库拉索芦荟的生长有一定的促进作用;在25%海水和50%海水浇灌下,芦荟多糖含量提高了2-3倍;在75%海水浇灌下芦荟甙含量增加了3倍多,在50%海水和100%海水灌溉下,其含量也增加了2倍多;当海水浇灌浓度超过25%后,库拉索芦荟的生长明显受到抑制,生物量降低,抽苔期推迟,同时,海水浓度的增加也导致芦荟叶中累积大量Na~+,从而使得芦荟叶中Ca~(2+)含量降低,但Mg~(2+)并没有受到海水浓度的影响;用浓度低于75%的海水浇灌库拉索芦荟可以降低剖面深度在0-100cm之间的土壤盐度;其抗氧化保护酶中超氧化歧化酶的酶活力相对保持稳定,过氧化物酶的酶活力在10%海水浇灌下明显提高,随后则下降,而过氧化氢酶的酶活力则随海水浓度的升高而下降。

Whereas, the tapetum of Zhenshan 97A disaggregated at the pollen mother cell stage, the nuclear membrane and the cell membrane disaggregated, the phenomena continued to the binucleate pollen stage. The cytoplasm of the tapetum cells of Zhenshan 97A deposited a few Ca^2+ precipitates at the pollen mother cell stage.

珍汕97A绒毡层细胞从花粉母细胞时期开始,细胞质内有少量颗粒状的Ca^2+沉淀;减数分裂时期,绒毡层细胞的内切向壁表面有大量大颗粒的Ca^2+沉淀;单核花粉时期绒毡层细胞周围集聚一层Ca^2+沉淀。

The main achievements of the project are as follows: 1 the hypothesis that a decrease in seed mass causes an increase in mean dispersal distance has been tested based on the experiments of weed dispersal by wind. The experimental results partly support the hypothesis. The results will help farmers to make an optimal strategy of weed control; 2 a statistic method for inferring probabilistic distribution function of a random variable has been developed, by which probabilistic distribution functions of weed species dispersal have been determined; 3 the reproduction structure of Bromus sterilis has been studied; 4 a more complex CA model with 25 neighborhood cells were built, which can simulate spread of a weed population. This work promotes developments in both theory and application of CA models; 5 the "mean law" in weed control has been proposed. Accordingly, the algorism of patch spring may be calibrated; 6 the "patch" and "true patch" have been mathematically defined so that herbicide can be efficiently applied; 7 simulation validates that initial configurations of weed will affect dispersal of its population and strategies of controlling it, or its distribution patterns affect its dispersal progresses.

主要完成的工作和取得的成果有:1)用实验证实了重量较轻的杂草种子并不一定飞得比较重的远,其结果有助于农民制订杂草的优化控制策略;2)发展了一种推断随机变量分布函数的统计方法并用它来获得了几个杂草种的扩散分布函数;3)对杂草Bromus sterilis的繁殖结构进行了研究;4)建立了一个具有25邻的较复杂的能模拟杂草扩散的CA模型,并在理论和应用方面促进了CA模型的发展;5)在杂草控制方面提出了&平均法则&,据此可对按块施药方法进行校正;6)精确地定义了&块&和&真块&以便在杂草控制中能更有效地使用除草剂;7)模拟证实杂草种群的初始配置影响其扩散和控制策略,或者格局影响过程。

The leaching and release of Ca~(2+) and HCO_3, the key elements for karstification, is characterized by a first high concentration but fast decreasing phase followed by a phase steady to equilibrium, indicating removal of readily mobile Ca and bicarbonate is involved in epigenic limestone dissolution as evaluated by karst water chemistry.

结果表明,岩溶作用使土壤中易移动性组分淋溶,Ca~(2+)、HCO_3~-的淋出动态表现为开始的快速下降和随之的平衡两个淋出阶段,淋出量与土壤中水溶性Ca、可氧化有机质的含量有关。土壤对HCO_3~-的淋出与排释有促进作用。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向,本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作,累计筛选1万多个/次样品,发现10余个活性较强化合物;从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究,分离鉴定了58个化合物,发现6个新化合物和14个抗肿瘤活性化合物;通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究,发现它可能是通过降低G2期重要的转录因子E2F-1,致使细胞周期阻滞在G0/G1期,引起多发性骨髓瘤U266细胞凋亡;开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析,结果表明计算与实验一致。

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在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

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