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Wherein X is an oxygen atom or a sulfur atom; C*, C** and C*** are asymmetric carbons; R 1 , R 2 , R 4 , R 5 , R 8 , R 9 and R 10 are each a lower alkyl group optionally having substituent and the like, or R 4 and R 5 and the like in combination optionally form a homocyclic ring optionally having substituent and the like; R 3 is an aryl group optionally having substituent and the like; R 6 and R 7 are each a hydrogen atom and the like; Nu is -CR 16 (COR 17 )(COR 18 ) wherein R 16 , R 17 and R 18 are each a lower alkyl group optionally having substituent and the like, and the like; and EWG is an electron withdrawing group.

通式中，X代表氧或硫；C *、C **和C ***分别表示不对称碳；R 1 、R 2 、R 4 、R 5 、R 8 、R 9 和R 10 分别代表任选取代的低级烷基等，条件是例如R 4 和R 5 可以相互结合形成任选取代的同素环等；R 3 代表任选取代的芳基等；R 6 和R 7 分别代表氢原子等；Nu表示-CR 16 (COR 17 )(COR 18 )(其中R 16 、R 17 和R 18 分别代表任选取代的低级烷基等)等；并且EWG表示吸电子基团。

And more, ERK contents between group A and B, group C and D were not dramatically different. The pathological lesions indicated that intestinal tissue necrosis was severe in group C and D, which were graded 3 points, but obviously lessened in group A and B, which was graded 1 point, with ITF interfering. Conclusion: Intestinal inflammation was ameliorated after ITF was injected hypodermically or intraperitoneally.

结果：A、B组组织匀浆中ERK的面密度值各为87.68±19.24、82.65±21.35，较C、D组(30.23±7.79、30.74±8.19)明显升高(P＜0.01)，C、D组与E组(5.41±1.46)比较也有升高(P＜0.05)；并且随著ERK的激活伴随著明显的核转位。A、B组间及C、D组间ERK含量无显著差异(P＞0.05)；病理切片显示C、D组HE染色切片见肠壁损伤轻重不一，可见全肠粘膜绒毛坏死，病理评分的中位积分为3分；A、B组肠上皮细胞少量脱落，顶端绒毛坏死，病理评分的中位积分为1分。

Methods 45 patients with GO were divided into four groups randomly, group B with anti-thyroid drugs, group C with anti-thyroid drugs and steroids, group D based on group C and additional retrobulbar injection with steroids, group E based on group C and additional intrathyroid injection with steroids.

45例GO分为4组：B组抗甲状腺药物治疗；C组同时口服强的松；D组：C组＋球后注射地塞米松；E组：C组＋甲状腺注射地塞米松和奥曲肽。

The Diels-Alder reactions forming one C—B bond and one C—C bond are always more favorable than the corresponding Diels-Alder reactions forming two C—C bonds, both thermodynamically and kinetically, which is in agreement with experimental observation.

形成一个C—B键的杂Diels-Alder反应都比相应的Diels-Alder反应在热力学和动力学上容易进行，这与实验结果一致。

Objective Detecting the protein expression of c-fos、c-jun and c-myc so as to inquire into its relation with knubbly invasion.

目的 检测c-fos、c-jun、c-myc基因蛋白在垂体腺瘤中的表达，探讨它们与肿瘤侵袭性的关系。

When reached logarithm growth phase, it was poured or the medium was removed. 5 mL medium containing 10 mg/L mitocin-C was added , kept at 37 ℃, and then cultured in saturated humidity warm box with the CO2 of 0.05 fraction volume for 2 or 3 hours. It was coated with 0.1% gelatin in 6-hole plate, laid for over 30 minutes, and then threw away or the medium with mitocin-C was removed, washed with phosptat buffer for 5 times so as to remove the mitocin-C. 2 mL 0.05% trypsin digestive cells were added, and it was observed under microscope. When crevice appeared, cells became round (about 2－4 minutes), digestion was stopped by adding medium of the same volume, and blew up with straws repetitively to make it into monoplast suspension. Special-used cover glass was put in the center of cell counting chamber. Cells were sucked in by glass siphon, and cell suspension flew out at bucket of up or down-sides of counting chamber, until the cover glass was filled with fluid. Living cell were inoculated at concentrations of 3×108, 5×108, 1×109 L－1 after their number counted.

选取2～5代的小鼠胚胎成纤维细胞，待其至对数生长期倒掉或吸掉培养基，加入含10 mg/L丝裂霉素C的细胞全培养液5 mL，置37 ℃，体积分数0.05的CO2饱和湿度温箱中培养二三小时，在6孔板中加入0.1%明胶包被，放置30 min以上，倒掉或吸掉含丝裂霉素C的培养基，磷酸盐缓冲液清洗5遍，尽量除去丝裂霉素C，加入2 mL 0.05%的胰蛋白酶消化细胞，镜下观察，当细胞间出现裂隙，细胞变圆时（约2～4 min），立即加入等量的全培养液终止消化，并用吸管反复吹打，使之成为单细胞悬液，在细胞计数板中央放置专用的盖玻片，用玻璃虹吸管吸取细胞，让虹吸管在盖玻片上或下侧的计数板凹槽处流出悬液，至盖玻片下被液体充满为止。

They all contain 13 protein coding gene,2 rRNA gene,22 tRNA gene and 1 D-Loop.The base composition for the four nucleotides is A-32.0%,C-27.6%,G-14.7%,T-25.8%,And it is A-32.5%,C-26.9%,G-14.1%,T-26.5%for Yellow-throated Marten.But there are some definite differences in base composition,the using of Initiation codon and Stop codon,and the mode of repeat sequences in control region.The codon usages of Manes have bias,and the ttiird locations of codon of protein-coding genes have the higher frequency in using A and C.There may be some relativity with the content of A and C in D-loop,namely,it has relation with the mode of repeat sequences.The complete mitochondrial genome of the Sable and Yellow-throated Marten were submitted to GenBank,and the accession number are FJ429093 and FJ719367 respectively.3、The complete mitochondrial genome of 6 other species of Mustelidae from GenBank and some sequences of D-loop from the 6 species were aligned.

分析紫貂大兴安岭亚种、长白山亚种、阿尔泰亚种和北欧亚种间的基因流及进化历史得知：大兴安岭种群与新疆种群和长白山种群间的基因流水平最高(Nm=0.1260和0.1427)，新疆与长白山种群间最低Nm=0.0053紫貂种群在进化过程中可能发生过种群膨胀，经历过种群增长过程。2、对紫貂和黄喉貂的线粒体全基因组结构进行分析发现：全长分别为16 523bp和16549bp，均包含13个蛋白质编码基因、2个rRNA基因、22个tRNA基因和1个非编码序列区(D-Loop区，紫貂全序列中碱基组成为A-32.0%，C-27.6%，G-14.7%，T-25.8%，黄喉貂为A-32.5%，C-26.9%，G-14.1%，T-26.5%；基因排列顺序与日本貂和貂熊的一致，但碱基组成、起始密码子和终止密码子的使用及控制区中串联重复序列模式等均存在一定差异。

Results The expression of eNOS mRNA at low concentration of C-peptide was lower than that of control group,the expressions of eNOS mRNAwere higher at physiˉological and higher concentration of C-peptide,but there was no difference between physiological and higher concenˉtration of C-peptide.

结果 低浓度的C肽(1ng/ml)使eNOS的表达减弱(P.01)；生理浓度的C肽(10ng/ml)和高浓度的C肽(100ng/ml)均可使eNOS的表达明显增强(P.01)。

New Zealand white rabbits (3-4 months old, 3-4 kg weight) were the test animals, and they were divided into three groups proceeding in this study. In group A:One PLLA screw and one commercial screw were implanted in the right tibia. Two PLLA screws were implanted in the left. Furthermore, one PLLA bar was implanted in both right and left tibia respectively with onlay model in group B. Also,one PLLA plate was implanted in the left tibia and one commercial plate in the right respectively with onlay model in group C . Many tests were done on each sample in 1, 4, 8 and 12 weeks which included the observation of tissue response in group A, and the change of three-points bending, weight loss, molecular weight, crystallinity and morphology of fracture surface by scanning electronic microscopyin group B, and the change of three-points bending, weight loss and molecular weight in group C.

所使用实验动物为24只3-4个月大，体重3-4公斤的纽西兰兔，并将所使用材料及动物分为A、B、C三组进行。A组中於实验兔之右胫骨植入两支骨钉，一支为自制骨钉，一支为MacroPore市售骨钉，并钻一孔但不植入骨钉做为控制组；另於实验兔之左胫骨植入两支自制骨钉，另标示一区不钻孔不植入骨钉做为控制组。B组采用onlay1 模式於实验兔之左右胫骨各植入一自制长型片。C组也采用onlay模式於实验兔之左胫骨植入一自制骨板，於右胫骨植入一市售骨板，各於不同时间点( 1， 4及12周)将A及C组，而於( 1，4，8及12周)将B组内的植入物取出进行各种测试，包括A组的组织切片观察及B组的三点弯曲变化、质量损失、分子量变化、结晶度变化及扫描式电子显微镜观察断面型态改变及C组的三点弯曲变化、质量损失、分子量变化。

Methods 20 rats were randomly divided into A, B, C, D and E group. The models of cerebral anoxia in group A and C were made by hypopiesia and hypoxia, and the models of hypoxia-reoxgenation were made in group B and D. 24h and 1h before establishment of models, ginsenoside Rb3 was injected peritoneally in rats of group C and D, respectively. The number and form of GABA-like immunoreactive neurons in hippocampus CA1 area of rats after brain hypoxia-reoxgenation were investigated with immunohistochemistry.

將大鼠隨机分为A、B、C、D、E5组，A、C组以低压低氧暴露製作大鼠脑缺氧模型，B、D组为缺氧－复氧模型。C、D组动物分别於制模前24h、1h 2次腹腔注射人参皂甙Rh3溶液；採用免疫组化法，观察各组大鼠在缺氧及缺氧－复氧处理后海马CA1区GABA免疫反应阳性细胞形態及数量的变化，並与正常对照组比较。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。