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Methods After the wide type NCI-H446 cells and the three kinds of NCI-H446 cells transfected by three kinds of IL-15 genes respectively （Cmp transfected by the IL-15 maturation peptide gene, Cp transfected by prototypic IL-15 gene, and Csp transfected by modified IL-15 gene whose signal peptide was replaced with the IL-2 signal peptide） were treated by mitomycin, the cells （named MCw, MCmp, MCp, and MCsp, respectively） were used as stimulator cells to stimulate PBMC from healthy volunteers.

野生型NCI-H446细胞和被3种IL-15基因分别转染的3种NCI-H446细胞（Cmp：被IL-15成熟肽基因转染；Cp：被原型IL-15基因转染；Csp：被信号肽换为IL-2信号肽的改型IL-15基因转染），用丝裂霉素处理后（分别名为MCw、MCmp、MCp和MCsp）作为刺激细胞刺激健康志愿者的PBMC。

The mian works are as follows:(1)By coprecipitation technique and coprecipitation- gel technique the nano zirconia powder was produced, factors affecting the properties of nano zirconia powder such as pH and the content of stabilizator are analyzed;(2)By the new pressless sintering process, the nano zirconia ceramic was produced, factors which can affecting the properties of nano zirconia sinter body such as moulding press and the sinter temperature are analyzed;(3)By the microtherm pressless sintering process, the nano copper added functional zirconia ceramic composite was produced, microscopic dimensionality and electric properties of such sinter body and the factors affecting such sinter body are analyzed;(4)By the self-invented "external albumen coating" technique the zirconia powder was successfully coated by carbon in the corresponding sinter body, which can help solve the traditional aggregation problem to some degree;(5)Based on analyze the characteristics in the nano powder sinter process, the "three-ball sinter model" was proposed, for the relationship between the relative density and porosity of sinter body, by mathematical fitting, such model was successfully verified.

本研究比较系统地研究了纳米氧化锆陶瓷的合成与成型机理，特别是讨论了纳米氧化锆陶瓷的稳定性，为防止纳米颗粒在外场作用下的团聚和长大提供了理论基础和实验数据，具体工作有以下几方面：(1)采用共沉淀法和共沉淀-凝胶法制备了纳米氧化锆粉体，并分析了pH值和稳定剂含量对粉体性能的影响；(2)采用新型无压烧结工艺制备了纳米氧化锆陶瓷，并分析了成型压力和烧结温度对烧结体性能的影响；(3)采用低温无压烧结工艺制备出添加纳米铜的功能性纳米氧化锆复合陶瓷，并分析了烧结体的微观尺度和电学性能的变化以及影响因素；(4)通过自创的&鸡蛋清外敷法&在真空镀膜台上对纳米氧化锆粉体进行包敷碳颗粒的表面处理，并采用真空烧结工艺制得相应烧结体，初步开始解决陶瓷烧结过程中团聚长大这一传统难题；(5)通过分析纳米颗粒在制备烧结体过程中的实际特点，提出了&三球烧结数学模型&，通过引入坯体相对密度和孔隙率的相对关系分析并通过自行编写的数学拟合软件，验证了这一数学模型。

The sizes of the self-assembly micelles of the amphiphilic block copolymers and the effects werestudied by dynamic light scattering and UV-visible spectrophotometer. The micelle sizes werelargely influenced bythe hydrophobic chain content in the copolymer, the properties of the solvent and the copolymer concentration in the organic phase. The morphology of the micelles was investigated by transmission electron microscopy. Theresults showed that the micelles appeared spheres with inner core and outer shell. The critical association concentrations were determined by pyrene monomer fluorescence probe technology. The degradability of copolymer was studied by the loss of the intrinsic viscosity in the degradation process. The results indicated that the degradation rate of PECL was slower thanthat of PELLA and PEDLLA. The stability of the copolymer micelle dispersion was examined by measuring the critical flocculation concentration, which gradually decreased with increasing the content of thehydrophobic chain in the copolymer. The rheological results showed thatthe viscosity ofthe micelle dispersion with higher content of PEG segments was firstly decreased and then increased with the increasingthe temperature. Otherwise, the variation of viscosity was irregular. The viscosity of the micelle dispersion increased with the increase of the electrolyte (Na 2SO 4) concentrations. Polymer micelles paclitaxel was prepared by self-emulsification/solvent evaporation method and solid dispersion technique with amphiphilic block polymers as the carrier material.

运用动态光散射和紫外分光光度计研究了两亲性嵌段共聚物自组装胶束的粒径及其影响因素，结果表明，自组装胶束的形成机理受制备方式的控制，胶束的粒径随着共聚物相对分子质量或疏水嵌段相对分子质量和有机相中共聚物浓度的增大而增大，随着有机溶剂的水溶性的增强而减小；采用透射电镜观察胶束的形态结构，发现胶束呈具有核壳结构的均匀球形；采用芘荧光探针法测两亲性嵌段共聚物的临界聚集浓度；通过降解过程中共聚物特性粘度的变化研究两亲性共聚物的降解性能，发现与PELLA和PEDLLA的相比，PECL 降解速率较慢；随着共聚物中疏水嵌段含量的增大，纳米分散液的稳定性逐渐下降；PEG含量高的PEDLLA纳米分散液随着温度的升高，纳米分散液的粘度先下降然后增大，反之，没有规律性，且随着电解质Na 2SO 4浓度的增大，体系粘度增大。

For preparing for the researches of text digital watermarking and advantaging other researchers" development when using the Chinese mathematical expression theory, this paper designs and realizes a development platform of Chinese mathematical expression. It has been proved by experiments that the platform"s function, execution speed and stability can satisfy the requirements of conversion and operation of enormous data.This research found out that the structure information of Chinese have plenty redundant information that can be used by the Chinese mathematical expression for the digital watermarking, the data embedded can possess better robustness. Based on this finding, this paper designs a kind of text digital watermarking method of embedding watermarking by using Chinese structure, and realizes the method by using the Chinese mathematical expression platform.Considering the watermarking embedding algorithms importance to the robustness of the text digital watermarking, this paper makes fully use of the advantage of the Chinese mathematical expression theory to design a kind of layered text method, which has being realized by using the Chinese mathematical expression platform. The layered text method can handle the text as a solid structure, and the embedding data havepreferable robustness.Finally, based on the researches of the text digital watermarking method and the text layered method, this paper integrates the method of making use of the Chinese structure embedding watermarking with the robust algorithm based on text layered, and realizes a brand-new text digital watermarking method. Proved by lots of experiments, this brand-new method has good robustness and better invisibility.

为了为研究工作做准备和方便其他使用汉字数学表达式理论体系的人进行开发，本文基于汉字数学表达式理论设计实现了一个汉字数学表达式平台，实现了Unicode汉字集中的汉字、汉字数学表达式、汉字的Unicode码之间的相互转化、依据汉字数学表达式提取汉字的结构信息、由汉字数学表达式在非中文平台上不依赖字库显示汉字的图像等功能，使用复合文档技术和流压缩技术进行数据的存储，使用对汉字数学表达式进行二叉树拆分来处理汉字数学表达式中包含的信息，使用自定义哈希函数来提高运行速度，实验证明，该平台功能、速度和稳定性完全能满足大量数据的转化和运算要求；通过研究表明汉字的结构信息中存在大量可使用汉字数学表达式理论加以利用的水印加载空间，加载在该空间的数据可以具有较好的鲁棒性，基于此，本文设计了一种利用汉字结构加载水印的文本数字水印方法，并使用汉字数学表达式平台将其实现；由于水印嵌入算法对于文本数字水印的鲁棒性至关重要，本文充分利用汉字数学表达式理论的优点，设计了一种文本分层的方法，并使用汉字数学表达式平台将其实现，使文本成为一个立体的空间，使嵌入在其中的数据具有更好的鲁棒性；最后在基于汉字数学表达式的文本数字水印嵌入方法的研究和基于汉字数学表达式的文本分层方法的研究的基础上，结合利用汉字结构嵌入水印的方法和基于文本分层的抗攻击文本水印嵌入算法实现了一种全新的文本数字水印方法，经实验证明，该方法有良好的鲁棒性和较好的隐蔽性。

In this paper, based on the theory of history course resource and by using traditional researching methods of "testifying history by arts""bilateral connection of arts and history", the way to construct the teaching model by combination of liberal arts and history, to analyze the literature in junior high school Chinese course (including Chinese textbooks, after school reading books and recommended masterpiece at home and abroad) to enrich the history teaching by inosculating the literature content in junior high school Chinese lesson into history teaching were explored in order to realize the resource sharing in the Chinese and history teaching and to achieve the state of "testifying history by the help of arts""explaining the arts by the help of history" and " inosculating arts into history".

本研究尝试根据历史课程资源理论和传统的&以文证史&、&文史互通&的史学研究方法，探索在初中历史教学实践中构建文史综合的教学模式，研究如何从课程资源的角度解读中学语文课程（包括语文教材、课外读本和推荐阅读中外名著）中的文学作品，将中学语文课程中的文学作品作为不可或缺的实证史料充实进历史课程，融入历史教学，实现初中历史与语文课程的资源共享，做到&以文证史&、&以史释文&、&融文入史&。

However, the piercing flavour of LuHsun"s essays made his essays subject to censure by many critics. And LuHsun himself was often mistaken and refuted by the compromising ones because of his sharping critical attitude toward one vital part but ignoring the other aspects of the objects. Especially those readers who never read the articles by LuHsun"s counterparts would think him too harsh, but the value of LuHsuns essays could be uncovered sufficienty by contrast to those by the counterparts.

鲁迅杂文深刻犀利的文风也多受指责；其对生活、社会问题看法超出一般人的理解范围而受误解；其只抓要害、不及其余以及连类而及，对具象的类型化批评的论辩方式为中庸、和为贵的受众所指责，尤其是难以见到鲁迅论辩对手文章的读者，更会留下刻薄的印象，因为鲁迅的现实性极强的杂文与对立之文共存才显现它的价值。

So that if, on the one side, we shall be traduced by Popish persons at home or abroad, who therefore will malign us, because we are poor instruments to make God's hold truth to be yet more and more known unto the people, whom they desire still to keep in ignorance and darkness; or if, on the other side, we shall be maligned by self-conceited brethren, who run their own ways, and give liking unto nothing but what is framed by themselves, and hammered on their anvil, we may rest secure, supported within by the truth and innocency of a good conscience, having walked the ways of simplicity and integrity as before the Lord, and sustained without by the powerful protection of Your Majesty's grace and favour, which will ever give countenance to honest and Christian endeavors against bitter censures and uncharitable imputations.

所以，如果问题的一个重要方面，我们应traduced由popish人在国内还是国外，因此，世卫组织将中伤我们，因为我们是穷人的文书，使上帝的真理，以尚未被越来越多的被称为祂的人，他们欲望仍然保持在无知与黑暗；或者，在另一边，我们应中伤自律自负，弟兄们，谁经营他们自己的方式，并让祂喜欢什麼，但什麼是诬陷自己，并敲定其铁砧，我们可以休息安全的，支持的，由真理和纯洁的一个很好的良知，有步行的方式简单化和完整性作为主面前，并没有持续的，由强大的保护国王陛下的恩典和赞成的，这将给予国家进行以诚实和基督教事业对痛苦的责难和uncharitable污名。

We can do so only by following the trail of blood and fire, by empathising with the young fighters, these ruined princes of American privilege, and by weltering in the horror of a war in which every outrage on the open field is matched by another, possibly worse, caught by the cameras of stealth – nightmares in night-vision.

我们只能循着鲜血与战火的痕迹去寻找，通过移情于这些年轻的战斗者、这些具有特权的堕落的美国公子哥儿，通过在战争的恐怖中挣扎，在这场战争中，每次公开暴行都堪与另一次相比，可能还会更惨烈，都被摄影机偷拍下来——夜间的可怕景象是用夜视摄影机拍摄的。

It is mainly formed by the reaction between urea (produced by the breakdown of arginine by the yeast) and citrulline (produced by the degradation of arginine by malolactic bacteria and ethanol).

葡萄酒中氨基甲酸乙酯主要由酵母降解精氨酸产生的尿素和苹果酸-乳酸菌降解精氨酸产生的瓜氨酸与乙醇自发反应产生。

Based on analyzing disadvantage of URT′s passenger flow forecast by the joint mode split\assignment model on all modes OD matrix, this paper presents a URT's passenger flow forecast with the joint mode split\model on cooperant and competitive OD matrix.Firstly, all modes OD matrix can be gained by trip production and distribution forecast. Secondly, coopperant and competitive OD matrix can be achieved by layered and politic mode split method. Lastly,URT forecast can be done by joint mode split\assignment model.

在分析基于全方式OD采用联合方式划分交通分配模型进行轨道客流预测不足的基础上，提出了一种基于合作竞争类OD的采用联合方式划分交通分配模型的轨道交通客流预测方法，即由出行产生和分布预测得到全方式的OD矩阵，通过分层次策略性交通方式划分法得到合作竞争类出行OD矩阵，然后采用联合方式划分交通分配模型进行轨道线网客流预测。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。