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For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此,本文以难溶性的格列齐特为模型药物,在传统型推拉式渗透泵的基础上,设计并制备了双面打孔型推拉式渗透泵;通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面,对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察,同时,应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究;在此基础上,通·药学论文过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定,结合流体力学中的Poiseuille层流定律方程,对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

For this reason, a novel PPOP was designed and prepared using two side drilling technology and water-insoluble drug gliclazide was employed as model drug. Influencing factors from six aspects were studied which was drug layer formulation, push layer formulation, coating formulation, orifice properties, tableting art and dissolution conditions, respectively, and the difference between the dissolution profiles of novel PPOP and conventional PPOP was also evaluated by similarity factor (f2). Through determination of the viscosity of drug layer and push layer of the novel PPOP, the mechanism of drug release from novel PPOP was discussed by the help of Poiseuille's law of laminar flow.

因此,本文以难溶性的格列齐特为模型药物,在传统型推拉式渗透泵的基础上,设计并制备了双面打孔型推拉式渗透泵;通过单因素研究从含药层处方、助推层处方、衣膜处方、释药孔性质、压片工艺以及体外释药条件六个方面,对影响双面打孔格列齐特推拉式渗透泵片释药行为的因素进行了详细的考察,同时,应用相似因子法对以上各种因素下双面打孔型推拉式渗透泵和传统型推拉式渗透泵释药特点的异同进行了系统的研究;在此基础上,通过对双面打孔型推拉式渗透泵含药层和助推层黏度的测定,结合流体力学中的Poiseuille层流定律方程,对双面打孔格列齐特推拉式渗透泵片的释药机理进行了较为深入的探讨。

That was the reason (as all men know, In this kingdom by the sea) That the wind came out of the cloud by night, Chilling and killing my Annabel Lee.

这是原因(如所有男人都知道,在这个由英国海)该风力出来的云之夜,寒蝉和杀害我annabel李。

Therefore the RMB appreciation is helpful for balancing China international balance of payment step by step, but the reason lead to the China international balance of payment surplus is profundity and complex especially to the cumulation of trade surplus, which is no only lead by undervalued RMB and improper form system of RMB exchange rate.

这说明虽然人民币升值有利于促进我国国际收支逐步趋于平衡,但是我国的国际收支顺差,尤其贸易顺差的累积&冰冻三尺,非一日之寒&,有着深刻、复杂的原因,不单单是由于人民币被低估或者人民币汇率形成机制不合理造成的。

On period " golden hill business management " the magazine published from " digging pit filling " the by-talk article that speaks of, from a 3 people working party, one person digging pit, telegraph pole of one person erect, one person filling, that person of inopportune erect telegraph pole because reason absent, and the person of filling of those two digging pit is illuminated dry a jest that do not deduce by accident are derivative be short of the impressions that break to business management target.

梗概: 上期《金山企业管理》杂志刊登了一篇从&挖坑填土&说起的杂谈文章,从一个三人工作小组,一人挖坑,一人架设电线杆,一人填土,不巧架设电线杆的那个人因故缺席,而那两个挖坑填土的人照干不误所演绎出的一则笑话引出对企业管理目标缺失的感想。

The main reasons and its correlated factors of the photoacoustic signal had been quantitatively analyzed based on signal absorption and photoacoustic rationale. It is found that the changed coupling coefficient of sound source and optical cavity modes which caused by the intensity of incident light absorbed by gas sample is the major reason, and a criterion was put forward for signal saturation depth estimating.

基于气体吸收和光声光谱原理定量分析了光声信号饱和的主要原因及影响因素,分析表明气体样本对入射光强吸收而导致的声源与本征共振模式的耦合系数改变是异常饱和的主要原因,并导出判定光声信号饱和深度的准则以用于判定高浓度气体饱和深度。

The rebounding damping technology, that the function in the same kinds of products sold in the market are not in common, means when you pull the drawer out to the bottom, it will has a process of soft closing and rebound, which can reduce the noise made by the things loaded in the drawer in efficiency. Moreover, because of the variable damping technology, which help to lessen the force of of the inertia made by the motion of the box when open or close it, and it will extend the useful life of the cabinet effectively. Therefore, it proved that the two-way slow motion cabinet have a longer useful life than the single soft-closing drawer system. And that is the reason why GRASS HOPPER is so popular in many countries all over the world.

反弹阻尼技术就是当你的橱柜抽屉拉到尽头时,有一个轻微的缓冲反弹过程,这样就减小了抽屉里面的装载物的碰撞声音,能达到更加实际意义上的静音,同时由于具备这种功能,在开合抽屉时就大大减小了由于抽屉的运动惯性对柜体产生的破坏力,这样就有效的延长了橱柜的使用寿命;所以使用双缓冲抽屉的橱柜比使用单缓冲抽屉的橱柜寿命明显延长,而市场上还没有具备这种功能的同类产品。

The rebounding damping technology, that the function in the same kinds of products sold in the market are not in common, means when you pull the drawer out to the bottom, it will has a process of soft closing and rebound, which can reduce the noise made by the things loaded in the drawer in efficiency. Moreover, because of the variable damping technology, which help to lessen the force of of the inertia made by the motion of the box when open or close it, and it will extend the useful life of the cabinet effectively. Therefore, it proved that the two-way slow motion cabinet have a longer useful life than the single soft-closing drawer system. And that is the reason why GRASSHOPPER is so popular in many countries all over the world.

反弹阻尼技术就是当你的橱柜抽屉拉到尽头时,有一个轻微的缓冲反弹过程,这样就减小了抽屉里面的装载物的碰撞声音,能达到更加实际意义上的静音,同时由于具备这种功能,在开合抽屉时就大大减小了由于抽屉的运动惯性对柜体产生的破坏力,这样就有效的延长了橱柜的使用寿命;所以使用双缓冲抽屉的橱柜比使用单缓冲抽屉的橱柜寿命明显延长,而市场上还没有具备这种功能的同类产品。

The first part is an exordium in the paper and introduces the reason,meaning of topic selection and research status and so on.The second part adopts literature research method to analyze the theories of equal and right from notion definition,properties,development and th.e discrimination on the concept,laying a theoretical foundation of claiming equal employment rights,correcting the wrong views and setting up right value judgment.The third is a difficult part and uses various methods synthetically to analyze facts that the equal employment right of college students has being infringed severely in detail,from inequality of social relations to the restriction of age,gender,household registration which setting by employing unit,it provides the powerful support that it is urgency for college students to claim equal employment rights currently.The four part of paper by using case analysis method enumerates several typical cases and points out the realistic meaning and deficiency of assertors' action.

本文分为五部分,第一部分为绪论,介绍了论文选题的原因、意义、研究现状等;第二部分运用文献研究法分析了平等和权利两大理论,从概念的诠释、性质、发展、辨析等方面奠定了大学生主张就业平等权的理论基础,从而在理论上纠正了现实社会的理解偏差,树立了正确的平等权利的理论价值判断;第三部分是难点部分,综合运用各种方法,详细剖析了大学生就业平等权利受到的种种侵害,从社会关系的不平等到用人单位设置的年龄、性别、户籍等不平等门槛,强有力的说明了大学生主张就业平等权的现实必要性和紧迫性;第四部分用案例分析法重点列举了大学生主张就业平等权的典型案例以及其现实意义与不足之处,从大学生的主张就业平等权的。

No inference is here intended that the laws provided by the States against false and defamatory publications should not be enforced; he who has time renders a service to public morals and public tranquility in reforming these abuses by the salutary coercions of the law; but the experiment is noted to prove that, since truth and reason have maintained their ground against false opinions in league with false facts, the press, confined to truth, needs no other legal restraint; the public judgment will correct false reasoning and opinions on a full hearing of all parties; and no other definite line can be drawn between the inestimable liberty of the press and its demoralizing licentiousness.

如果仍然有此规则无法限制的不恰之处,则须在公众舆论检查中寻找它的补充。现在我将要履行我的同胞再次召唤我的职责,并将要以他们所认可的那些原则的精神来履行。我无惧于任何可能使我迷途的利益目的;我没有感到任何能引诱我明知是离开公正之途的欲望,但是,人性的弱点和我自身感知的局限将会造成对你们利益有损的错误判断。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在,'歼灭战perfuming自己与胡努特,那麼,他来到和SAT 。

The shamrock is the symbol of Ireland and of St.

三叶草是爱尔兰和圣特里克节的标志同时它的寓意是带来幸运。3片心形叶子围绕着一根断茎,深绿色。