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We built the 3D structure of hAChE by homologous modeling method. The model of hAChE complexed with THA, GAL and THA were also built. By studying these models, we found that the aromatic packing force is important in the inhibitor binding to the hAChE.

通过构建和研究hAChE的同源结构模型及其与抑制剂的复合物结构模型，我们发现芳香环的堆积作用在抑制剂与受体的结合中起重要的作用。

In this paper, asymmetric synthesis of oxidation reaction of achiral isophorone influenced by artificial centrifugal force field was studied. The reaction system was characterized by UV, Infrared and Circular dichroism.

摘要本文通过紫外、红外和圆二色光谱表征考察了外在离心力场对非手性化合物异佛尔酮不对称氧化生成光学活性产物的影响。

In this paper, asymmetric synthesis of oxidation reaction of achiral isophorone influenced by artificial centrifugal force field was studied. The reaction system was characterized by UV, Infrared and Circular dichroism.

本文通过紫外、红外和圆二色光谱表征考察了外在离心力场对非手性化合物异佛尔酮不对称氧化生成光学活性产物的影响。

Result 1 Magnetic nanoparticles, magnetic nanoparticles modified with antisense oligodeoxynucleotide of human telomerase reverse transcriptase induced HL-60 tumor cells to apoptosis, we could see typical morphologic change of apoptosis cells: karyopyknosis, chromation"s condensing and aggregation in nuclear, forming crescent-shaped or annulus structures to lean on edge of cell nucleus"s membrane and posing apoptosis body by Atomic Force Microscope, Fluorescence microscope, transmission electron Microscope 2 There was a significant difference compared with control group(p.01), inhibition ratio had significant positive correlation with medication dosage and time ;during 0.8-8μM dosage amplitude, inhibition ratio accrescenced by dosages increasing. However, the inhibition ratio would decrease when dosage over 8-80μM.

结果 1 磁性纳米粒子、修饰有端粒酶反义寡核苷酸的磁性纳米粒子诱导HL-60细胞发生凋亡，原子力显微镜、光学显微镜、荧光显微镜和透射电镜下均观察到HL-60细胞呈现典型的凋亡细胞的形态变化：细胞核固缩，核内染色质浓缩、凝聚、形成新月形或环状结构紧靠在细胞核膜边缘，并形成凋亡小体。2 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子对HL-60肿瘤细胞的生长和增殖有明显的抑制作用，与对照组相比有显著性差异(p＜0.01)，在剂量为0.8-8μmol／L范围内，抑制率随剂量的增加而增加，当剂量超过8μmol／L时，抑制率反而下降；3 磁性纳米粒子、修饰有端粒酶反义寡聚脱氧核苷酸的磁性纳米粒子可增强p53基因的表达活性，引起DNA降解损伤，反向调节细胞周期活动，促使细胞从G0期进入G1期，抑制肿瘤细胞的生长。4 修饰有端粒酶反义寡聚脱氧核苷酸的量子点能通过内吞作用进入HL-60肿瘤细胞的细胞核，可以在细胞内进行定位和促进HL-60肿瘤细胞的凋亡。

For a gas medium, the levitation force is determined not only by the ratio of its density to sound speed, but also by the ratios of its wavelength to the geometric parameters of the levitator.

发现不同媒质中产生的最大悬浮力不仅取决于媒质密度与声速之比，还取决于该媒质的波长与悬浮器几何参数的相对大小。

METHODS: The morphological architectures of three HCC cell lines with the identical genetic background and different property of metastasis, including SW620, SW480 (hematogenous and lymphangitic metastasis) and SW480/M, were observed by light microscopy and atomic force microscopy, and the expression of carcinoembryonic antigen, CD44v5, Fascin and proliferating cell nuclear antigen in those cell lines were detected by immunohistochemical method.

对3种遗传背景一致，具有不同转移特性的大肠癌细胞株SW620、SW480SW480/M细胞的形态结构进行原子力显微镜和光镜观察，以及应用免疫组化技术检测CEA、CD44、Fascin、PCNA在3种细胞的表达。

From the sterile desert inhabited by grotesque cowboys to the junkyard haunted by male violence, the scene has kept evolving, until the introduction of the female view into the picture finally transforms the desolate landscape. This researcher would point out that Shepard not only resists the conventional Western performance but also proves himself to be neither a sexist nor a masculinist, as some critics have labeled him. On the contrary, he emancipates the western landscape from the dominance of patriarchal force and masculine violence through his revisions of the West.

从荒瘠不毛的沙漠，纯男性暴力的垃圾场，最后注入女性观点改造了原本荒凉的地景，谢柏的西部一直在演进发展，而非落入操演西部的窠臼，另一方面也显示了谢柏并非许多评论者认为的阳刚主义男性作家，实际上他解放了长久以来被父权意识形态与阳刚暴力驱控的西部地景

From the sterile desert inhabited by grotesque cowboys to the junkyard haunted by male violence, the scene has kept evolving, until the introduction of the female view into the picture finally transforms the desolate landscape. This researcher would point out that Shepard not only resists the conventional Western performance but also proves himself to be neither a sexist nor a masculinist, as some critics have labeled him. On the contrary, he emancipates the western landscape from the dominance of patriarchal force and masculine violence through his revisions of the West.

从荒瘠毛的沙漠，纯男性的垃圾场，最后注入性观点改造原本荒凉的地景，谢柏的西部一直在演进发展，而非入操演西部的窠臼，另一方面也显示谢柏并非许多评者认为的阳刚主义男性作家，实际上他解放长久以被父权意形态与阳刚驱控的西部地景。

An evaluation of Linear, Freundlich and Langmuir equations on both accuratity and stability indicates that the Linear equation is the best. Sorption of p nitrophenol to sediment is dominated by the partition of solutes to sedimental organic matter. The influences of temperature on sorption of p nitrophenol to sediment was also investigated. The sorption parameters of thermodynamics,Δ H =-7 8?kJ·mol -1 , suggest that the sorption behavior is dominated by dispersive force.

研究了对硝基苯酚在不同沉积物上的吸附等温线，比较分析了Linear方程、Freundlich方程和Langmuir方程描述吸附等温线的准确性和稳定性结果表明，Iinear方程更适合描述沉积物吸附对硝基苯酚的等温线对硝基苯酚在沉积物上的吸附主要是溶质在沉积物有机质中的分配，其吸附热为-7 8 kJ·mol-1，主要的吸附作用力为疏水键力。

The treatment to periodontal disease is mainly combined therapy,which control inflammation by periodontal medicine and operation;adjust interlocking,eliminate dental wound,relieve the burden of peridental supporting tissue by recovery treatment;fix the loose teeth,disperse the bite force,control the patho-loose and displacement,elevate the masticatory efficiency,make the troubled teeth to rest,is benefit to the control to periodontal inflammation and the healing of destructed periodontium.

牙周病治疗主要是综合治疗，通过牙周药物治疗、手术治疗来控制炎症；通过修复治疗调整咬合，消除牙创伤，减轻牙周支持组织的负担；固定松牙，分散力，控制病理性松动和移位，提高咀嚼效能，使患牙得到生理性休息，利于牙周炎症的控制和已破坏的牙周组织的愈合。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。