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Administration of 2.5-40μmol/L PDTC for 24-72 hours could significantly inhibit HPF proliferation in a dose-and time- dependent manner. CONCLUSION:The inhibition effect of PDTC on HPFs is significantly, which is dose- and time-dependent.· KEYWORDS: PDTC; human pterygium fibroblast; prolifera- tion

PDTC对体外培养的HPF细胞有抑制作用，在一定浓度和时间范围内抑制作用呈剂量与时间依赖性。

This project also obtained several limit theorems for some important dependent random variables and stochastic processes, such as the Strassen law of the iterated logarithm for negatively dependent random variables, strong limit theorems for mixing random vectors in Banach spaces, sample path properties for two-parameter fractional Wiener processes, and so on.

随机环境中的随机变量与随机过程的研究在国内外相当活跃，本项目主要研究它们的极限性质，着重研究了随机风景中随机变量与随机过程的极限性质，主要取得了以下几个结果：首先对简单对称的Kesten-Spitzer随机游动在低阶矩的条件下给出了强逼近，大大减弱了前人要求任意阶矩的条件，然后对独立风景中的一般随机变量给出了强逼近的一般性结果，由此导出在风景和随机变量都只具有低阶矩的条件下的独立但不同分布、混合相依变量的强逼近，在只有弱高于二阶矩的条件下得到了重相对数律和弱收敛；给出了连续时间参数的Brown风景中Brown运动和稳定风景中稳定过程的滞后增量和连续模等精确样本轨道性质；同时给出了一些重要的相依随机变量和过程的若干极限定理，如负相关随机变量的Strassen重对数律、抽象空间上混合相依变量的一些强极限定理成立的充分必要条件、两参数分数Wiener过程的样本轨道性质等。

In many ways we are largely dependent on China, and it is dependent on us as well.

在很多方面我们已经非常的依赖于中国了，当然这也取决于我们。

Based on the logic dependent relation and first-order logic, AND/OR graphs of single target with unit agent, and single target with multi-agent, joint targets with multi-agent were gotten respectively. As an example, single target with multi-agent was used to illustrate AO(superscript *) searching algorithm of logic dependent relations.

在分析逻辑依赖关系与一阶谓词表示法基础上，分别给出了单agent单目标、多agent单目标、多agent联合目标的逻辑依赖关系的与／或图表达方法，并应用与／或图的AO搜索算法，以多agent单目标情形为例，演示多agent系统中逻辑依赖关系的计算过程。

The typical apoptotic morphological features appeared in MUTZ-1 cells treated with 4mmol/L VPA for 72hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dose-dependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dose-dependent manner, the cells were arrested at G0/G1 phase.

结果显示：VPA对MUTZ-1细胞的生长抑制作用呈现时间和剂量依赖性；经4mmol/LVPA处理MUTZ-1细胞72小时后，细胞呈现典型的凋亡形态特征，光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体；透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加，胞装内大小不规则的染色质团块；流式细胞术结果表明，细胞凋亡率随着VPA浓度的增加而逐步增高，G0/G1期细胞比例随着VPA浓度的增加而逐渐增多，S期细胞比例逐渐减低，细胞被阻滞在G0/G1期。

We investigate phenomenologically effects of the flavor-dependent quarkonia annihilation on the meson-meson mixing, and find that corrections due to the flavor-dependent quarknoia annihilation can be described by the constituent quark masses in the mixing model which holds for all the meson nonet. We also study the relation between Regge trajectory and meson spectrum, and therefore concluded that the quasi-linear Regge trajectory with the requirements of additivity of intercepts and inverse slopes can describe the meson spectroscopy with good accuracy, and it also holds for the radial excited mesons except for the bbbar mesons.

我们唯象地研究了味道有关的夸克偶素湮灭效应对混合的影响，发现味道有关的夸克偶素间的湮灭引起的修正可以通过组分夸克的质量来描述，考虑这种修正的混合模型可以用于所有的介子九重态；我们也研究了Regge轨迹和介子质量间关系，发现满足截距相加及斜率倒数相加的准线性Regge轨迹可以很好地描述介子的质量，除bbbar外，线性Regge轨迹也可以很好地描述介子激发态的质量；最后，我们借助于赝标介子和标量介子，讨论多个共振态的混合及衰变。

Results: The proliferation of Kasumi-l cell was obviously inhibited by VPA on dose- and time-dependent manner. The IC50 was 2.33 mmol/L treated with VPA for 72 h. Incubation with VPA, the cell ratio at G0/C1 phase increased. VPA induced myeloid cell differentiation antigen CD11b to increase with a time-and dose-dependent way and caused apoptosis. Wright's staining and light microscope were used to show the morphology of partial differentiation and obvious apoptosis with 3 mmol/L VPA for 72 hours. The typical DNA ladder of apoptosis characteristic was observed with DNA gel electrophoresis.

结果：VPA能显著抑制Kasumi-1细胞的增殖，且呈剂量和时间依赖性，VPA处理Kasumi-1细胞72h时的半数抑制浓度(IC50)为2.33 mmol/L；VPA处理后，细胞周期检测G0/G1期细胞比例逐渐增高；VPA能诱导髓系分化抗原CD11b表达水平的阳性率升高，呈时间及剂量依赖性；VPA能诱导Kasumi-1细胞凋亡，Kasumi-l细胞经VPA3 mmol/L处理72h后，出现典型的凋亡细胞所具有的梯形DNA条带。

Results: Among 32 tested MNs, depolarizing responses(excitatory postsynaptic potential, EPSP) were elicited by cVLF stimulation in 21 MNs, hyperpolarizing response (inhibitory postsynaptic potential, IPSP) in 1 MN, and IPSP preceded by EPSP in 4 MNs. The cVLFEPSPs were stimulus intensity-dependent, and could be abolished by low Ca(superscript 2+)/high Mg(superscript 2+) solution. compared with iVLF-EPSPs, cVLF-EPSPs showed longer latency (P.001). The cVLF-IPSP presented with membrane potential-dependent property and was eliminated by the perfusion of picrotoxin (30 μmol/L) and strychnine (1.0 μmol/L).

结果：在32个测试的MNs，观察到cVLF电刺激可在21个MNs上诱发去极化反应（即cVLF性兴奋性突触后电位，cVLF-EPSP），在1个MN上诱发超极化反应（即cVLF性抑制性突触后电位，cVLF-IPSP），在4个MNs上诱发cVLF-EPSP后复合有cVLF-IPSP的反应。cVLF-EPSP具有刺激强度依赖性、被低钙高镁溶液取消的特性，与i VLF性EPSP相比，有潜伏期较长的特点(P.001)。cVLF-IPSP呈膜电位依赖性，并被印防己毒素(30μmol/L)及士的宁(1.0μmol/L)取消。

Firstly, based on the method of pressure-velocity coupling introduced by SIMPLE algorithm and a revised method of solving the unsteady equation of stream function and vorticity on uniform grid, a special algorithm called primitive-variable-time-dependent approach is formed in the present study. In this algorithm the Navier-Stokes equation in primitive variable form is solved by using the time-dependent approach on non-uniform staggered grid system. The second-order accuracy finite difference is used for the first and second partial derivatives of all variables of the convective terms and diffusion terms.

首先，本文在SIMPLE算法系列处理速度与压力耦合问题的思路和均匀网格下改进的关于流函数涡量方程的数值求解方法的基础上，将非定常原始变量Navier-Stokes方程的求解推广至非等距交错网格剖分，形成了具有本文特色的原始变量时间推进方法，其中对流项和扩散项中各变量的各阶导数均采用二阶精度公式，包括温度在内的离散方程组采用ADI迭代方法求解。

PYM and BLM could effectively inhibit the growth and proliferation of ECV304 cells and the effects were time-dependent and dose-dependent.

分别采用光镜、电镜和免疫组化方法，观察各时间点不同节段肾血管和组织的显微结构、超微结构改变以及PLE组肾脏组织FGF~2蛋白表达变化。

In the days of sailing vessels the crew were afraid they would be becalmed on the ocean.

在使用帆船的时代，船员们担心他们会因为无风而无法在海洋上航行。

As long as foreign donors pay the PA's salary bill, few expect a new intifada.

只要外国继续为巴权力机构的薪水买单，希望发动新暴动的人便寥寥无几。