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Through simulation of the real process of thomcolumbar burst fracture and use of modem dynamics techniques, the present study was (1) to investigate the kinetic relationship between structural damage and impact energy absorption and dynamics mechanism of thoracolumbar burst fracture by quantitative analysis of various injured segments;(2) to explore the instability mechanism of L1 vertebral burst fracture and its injury threshold by three-dimensional analysis of the injured segment with stereophotogrammetry in combination of transient physical parameters, anatomy and image;(3) to explore the corresponding relationships between impact energy, geometry parameters and biomechanics by geometry and biomechanical analysis of thoracolumbar burst fracture, which may provide an objective standard for evaluation of spinal injury severity and experimental evidence for adoption of biomechanical treatment in clinic;(4) to evaluate the fixation effect of different instruments and the effect of intervertebral bone graft on segment fixation by analysis of the threedimensional stability of different internal fixation instruments and their decompression of the spinal canal, which may provide experimental evidence for therapeutical selection for thoracolumbar burst fracture in future; and finally to investigate the effect of various instrument fixation on dynamical characteristics by comparison and quantitative analysis of frequency and amplitude responses, which may provide certain theories and experimental evidence for application of vibration test to judge the stability of the spine.
本研究从胸腰段脊柱爆裂骨折发生的实际过程出发,以现代动力学检测及计算机多通道高性能数据采集分析系统等高新技术为基础,实时量化分析损伤节段的工程参数,揭示了结构破坏与能量吸收的变化规律,探讨了胸腰段脊柱爆裂骨折的瞬态损伤机制;利用三维立体摄像技术,对不同损伤程度的节段进行三维运动分析,结合瞬态物理参数、影像学和病理解剖,明确了〓椎体爆裂骨折的失稳机制及损伤阈值;通过对胸腰椎爆裂骨折的几何学变化及生物力学分析,明确了撞击能量与几何参数、几何参数与生物力学的相应关系,为评判脊柱损伤程度提供了客观标准,为治疗中采取适宜的生物力学方法提供了实验依据;通过对比分析不同内固定器械的三维稳定性和对椎管的减压作用,评价不同器械的复位固定作用,同时比较椎体间植骨对节段固定作用的影响,为今后临床胸腰段脊柱爆裂骨折的治疗选择提供依据;利用振动测试与分析技术,比较及量化分析了不同致伤状况的频幅响应特征,比较分析了各种器械固定对动力学特性的影响,为今后临床建立基于振动测试与分析技术判断脊柱稳定性的诊断方法,提供了一定的理论和实验依据。
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The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.
本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。
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This article that focuses on the systematic and in-depth research in the current primal problem about abnormal burst pressure reservoir depress burst pressure has procured following main fruits:1 It forms the method which could obtain massive vertical static state mechanics parameters.2 In a foundation of acquisition of rock mechanics parameters,apply bent lamella that as mechanical model along with characteristic of actual geologic characteristics to analysis curvature for anticlinal strcture, get homologous tectonic stress value throug relation between the curvature and stress and different principal curvature in anticlinal structure,consequently set up laminational stress model for anticline reservoir. The block lamination for existed fracturing date has formed method of setting up mechanical model of lamination terrestrial stress by abtaining the block tectonic stress coefficients which are got by complex utilization test, laboratory test and fracturing date playback.3 Analysesing the main reason which lead to high burst pressure by considering the characteristic of reservoir geology,reservoir,and rock mechanics and reservoir damage,etc.Establishing burst pressure quantitative prediction model which provide gist for depressing construction risk and optimizing construction craft under the condition of open hole completion ,gun-perforated completion and damaged reservoir.4 Provding theoretical basis for interpreting acidification pretreatment which could depress busrt pressure by finding the relation between the influencing factors and rock machanics parameters and analysing the factors that have effect on rock mechanics parameters. Expounding the mechanism of reaction of mixed monomineral and acid from the angle of microcosmic element, evaluating quantitatively acid sensilility of different kinds of mineral effectively, and determing the first-order reaction dynamical equation of each mineral.5 Revealing rock mechanics property chage as a result of acid flooding in different condition by sandstone traumata experiment in different temperatures which combined with rock mechanics triaxial stress experiment.6 Associating damage mechanics with sandstone acidizing, established sandstone damage mechanics model in the foundation of the recognition on the rock mechanics parametric variation which is caused by acid-rock reaction in both macroscopic view and microscopic view ,also demonstrated those processes and quantitative estimated the acid busrt pressure to direct the site operation.
本文针对目前异常破裂压力储层降低破裂压力的主要问题展开较为系统和深入的研究,取得了以下主要成果:1形成了利用测井资料,结合室内岩芯测试结果,获取静动岩石力学参数的相关性特征,从而获得纵向上大量静态力学参数的方法。2在获取了岩石力学参数的此基础上,利用弯曲薄板作为力学模型,结合区块实际地质特征对背斜构造进行曲率分析,通过曲率与应力的关系,利用背斜构造不同部位的主曲率求得相应的构造应力值,从而建立起背斜储层的分层应力模型;对已有压裂资料的区块分层,形成了综合利用测试、室内实验、压裂资料反演获得该区块构造应力系数,建立起分层地应力的力学模型的方法。3综合考虑储层地质、油藏、岩石力学特性和储层伤害等因素,分析造成高破裂压力的主要原因,综合利用岩石力学、弹性力学等知识,建立了裸眼完井、射孔完井条件下以及储层受到伤害后的储层破裂压力定量预测模型,为降低施工风险和优化施工工艺提供了依据。4完成了物性、岩性影响岩石力学参数的因素分析,找出了各影响因素和岩石力学参数之间的关系,为从机理上解释酸化预处理降低破裂压力提供了理论基础;从微观元素的角度阐述了单矿物与酸反应的机理;并在此基础上,有效评价了各种矿物的酸敏感性,定量确定了岩石中各矿物的一级反应动力学方程。5完成了不同温度下的酸液类型、酸液浓度、注酸量等一系列砂岩损伤实验,结合岩石力学三轴应力实验,系统揭示了在不同条件下注酸而引起的岩石力学性质变化。6将损伤力学与砂岩酸化相结合,在宏观、微观两个方面认识酸岩反应引起岩石力学参数变化基础上,建立了砂岩损伤力学模型,并对其进行验证,在此基础上定量计算酸化后的破裂压力,有效指导现场施工
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Some methods to monitor and forecast the rock burst have been held, such as critical point, deviation values. KBD5 apparatus has been used to monitor the seismicity and rock burst of 4# coal seam's working face which has high danger of rock burst in coal mine. Many times of rock burst danger were forecaste
采用电磁辐射监测仪对某矿具有严重冲击危险的四层煤工作面进行了矿震和冲击矿压危险监测,有效地预测出了多次冲击危险,取得了良好的效果。
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Since I believe in "East Is Red," the old brand, so companies with a delayed sale and purchase agreement signed two forklifts. April 26, 2008, dragging the company into a new car to me, use less than two hours a fault occurs in less than a mere month, failed 15 times, cars have been a clutch not working, and hydraulic devices seal ring burst, and multi-way valve is broken, machine feet vibration failure, and inner tubes burst, pipeline burst, and bearing flowers, and water pump leaks, and brake drum is broken, cracked brake pads such as a host of problems, their Quality not as good as a second-hand car, even the "classic cars" also arrived not be reached.
由于我轻信&东方红&的老品牌,于是与一拖公司签定了两台叉车买卖协定。2008年4月26日,一拖公司把新车发给我,使用不到两小时就出现了故障,不到短短一个月,出现故障15次,车子先后出现离合器不灵了,液压器密封环爆裂了,多路阀坏了,机脚减振失效了,内胎爆了,油管爆裂了,轴承开花了,水泵漏水了,刹车鼓破了、刹车片裂了等一大堆问题,其质量不如一台二手车,甚至连&老爷车&还抵不上。
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General pouring a bowl of double-face, is the extreme delicacy, shrimp, the only river shrimp, head can be more or less, but again, even if small, the reduction flavor, use lard fried, so very incense; burst eel , Shansi to the deep-fried crisp, and then close soy sauce, and eat eel surface burst, you can spend a few dollars to buy a small ginger small dishes, on the surface, eating together, Bieyoufengwei This is the food connoisseurs Law; stew meat is very unusual, so is said to have really cooked stew, is a basic white-burning, are the basic fat lard into a massive import of that is, eat right, cover the meat is in Surface, to return from a slight temperature when to eat, not only as a thermal cover the meat, cover will not be too long, and let melt fat in the soup; burst fish, also known as smoked fish, and Shanghai is almost here, but will taste a little sweeter.
一般浇一碗双面,是极端的美味,虾,虾的唯一河流,头部可以或多或少,但是,即使小,减少风味,使用猪油炒,所以很香;爆裂鳗鱼,山西的炸脆,然后关闭酱油,吃鳗鱼表面爆裂,你也可以花几美元买一个小生姜小餐具,表面上,吃在一起, Bieyoufengwei这是食品鉴赏家法;炖肉是很不寻常的,所以据说,真正煮熟焖,是一种基本的白燃烧,基本脂肪猪油发展成为大规模的进口就是,吃的权利,包括肉的表面,以回报略有温度什么时候吃,不仅是一个热涵盖肉类,包括不会太长,让融化脂肪汤;爆裂鱼,也被称为熏鱼,上海几乎是在这里,但味道有点甜。
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A vertebra that fractured in the fall.(9) Burst implies a sudden coming apart, especially from internal pressure, and the dispersion of contents:The child burst the balloon with a pin.Her appendix burst.
在线词典目前并不支持任何通配符也不支持模糊查找,如果你不知道英文具体写法请输入汉语查找相对应的英文,反之亦然。
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Based on the comparison of the delayed neutron counter rate of known fission rate with the delayed neutron counter rate of a burst,a method to determine burst total fission number of burst reactor was built.
用长计数器测量已知裂变率的缓发中子计数率,然后用同一探测系统测量脉冲后的缓发中子计数率,探测系统的探测效率、缓发中子份额和缓发中子先驱核半衰期等参数均不变,从而建立起利用脉冲堆脉冲后的缓发中子衰减曲线确定脉冲裂变总数的方法。
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The progect has got the imbursement of progect named "burst modereceiver/ transmitter in broadband access network"(NO:2002AA101A04).The accomplishment of the 155Mb/s burst mode receiver makes essential conditions for the accessing of optical fiber to the common families and estabiishs a theory and technical foundation of the developing burst mode Receiver/Transmitter of the speed over 155Mbit/s.
本课题的研究得到项目&宽带接入网突发式光发射和接收模块&(项目编号:2002AA101A04)的资助。155Mb/s突发式光接收模块的研制成功为光纤进入普通家庭创造了基本的条件,也为以后开发155Mb/s以上速率的突发式光收发模块奠定了坚实的理论和技术基础。
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She is not in the washroom and then stopping, because it is finally his own point of view that he cares about and not hers, and with this firmly in mind, and a light, confident step, such as you might find in the works of Bulwer-Lytton, he enters the space she occupies so prettily and, taking her by the hand, proceeds to tear off the stiff white hospital gown (but no, we cannot have that kind of pornographic merde in this majestic and high-minded sentence, which will probably end up in the Library of Congress)(that was just something that took place inside his consciousness, as he looked at her, and since we know that consciousness is always consciousness of something, she is not entirely without responsibility in the matter) so, then, taking her by the hand, he falls into the stupendous white puree of her abyss, no, I mean rather that he asks her how long it has been since her last visit, and she says a fortnight, and he shudders, and tells her that with a condition like hers (she is an immensely popular soldier, and her troops win all their battles by pretending to be forests, the enemy discovering, at the last moment, that those trees they have eaten their lunch under have eyes and swords)(which reminds me of the performance, in 1845, of Robert-Houdin, called The Fantastic Orange Tree, wherein Robert-Houdin borrowed a lady's handkerchief, rubbed it between his hands and passed it into the center of an egg, after which he passed the egg into the center of a lemon, after which he passed the lemon into the center of an orange, then pressed the orange between his hands, making it smaller and smaller, until only a powder remained, whereupon he asked for a small potted orange tree and sprinkled the powder thereupon, upon which the tree burst into blossom, the blossoms turning into oranges, the oranges turning into butterflies, and the butterflies turning into beautiful young ladies, who then married members of the audience), a condition so damaging to real-time social intercourse of any kind, the best thing she can do is give up, and lay down her arms, and he will lie down in them, and together they will permit themselves a bit of the old slap and tickle, she wearing only her Mr.
然后阻止,因为到最后那是他自己的关心的观点而不是她的,在他的脑子里根深蒂固,他自信地走了一步,这就像你也许会在布尔沃?里顿的作品中看到的一样,他进入兴高采烈地进入她占有的空间,抓住她的手,开始撕开他白色僵直的病号衣(但是我们没有在他冠冕堂皇的充满智慧的语句中发现那种带有色情的废话,那也许会在国会图书馆中绝迹)(在他的意识中有一些东西正在被替代,当他看她的时候,就如我们知道的意识始终是意识,她在这个事情中不是完全没有责任的),所以,然后抓起她的手,他掉进了她深渊的巨大白色水中,不,我想他问她自从她上回来已经多久了,她说有两个星期了,他战栗着告诉她她现在的情况(她是一个非常受欢迎的女兵,她的部队通过埋伏在森林里赢得了所有的战斗,在最后的时刻敌人发现了,那些他们吃掉他们午餐的树有了眼睛和剑)(这使我想起了一八四五年罗伯特?乌丹的演出,叫做《奇幻橘子树》,在其中罗伯特?
- 相关中文对照歌词
- Extinction Burst
- Chris Benoit (Kuma's Scrub Club Remix)
- In The Middle
- Red Balloons
- Pardon Me
- Fire
- Into The Blinding Light
- Chase
- Coca Loca
- I'm Into You
- 推荐网络例句
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We should pay more attention to the children who lack parental control.
我们应该更多的关注那些缺少父母管教的孩子。
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And the priest's heart was glad, and he took the ephod, and the tera phim, and the graven image, and went in the midst of the people.
祭司心里喜悦,便拿着以弗得和家中的神像,并雕刻的像,进入他们中间。
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But, now, I came back.
但,现在,我回来了。