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Methods The expressions of Rb protein were detected in 52 patients with breast cancer, 20 patients with breast fibroadenoma or breast cystic hyperplasia by S-P immunohistochemical method.

采用S-P免疫组织化学染色法对52例乳腺癌组织和20例良性乳腺病变组织中Rb蛋白的表达进行检测。

Methods:SP immunohistochemistry staining was applied to detect the expression of p130Cas and paxillin in tumor tissues from 53 cases of primary breast carcinoma, 10 cases of breast fibroadenoma and in 10 cases of normal breast tissues.

采用免疫组化SP法检测53例原发乳腺癌,10例乳腺纤维腺瘤,10例正常乳腺组织中p130Cas和paxillin蛋白的表达情况。

Expression of MDR1 gene was measured with the fluorogenic quantitative RT-PCR method in 49 cases of breast cancer and 16 cases of control group (including 8 cases of benign breast lesions and 8 cases adjacent breast tissues). In addition, immanohistochemical analyses was used to detect the expression of P-gp and C-erbB-2 protein in above mentioned tissues.

采用荧光定量RT-PCR法检测49例乳腺癌,16例对照组(包括8例乳腺良性疾病、8例癌旁组织)中MDR1基因的表达,同时采用免疫组化检测表述标本中P-gp及C-erbB-2蛋白的表达。

Inframammary fold is an important structure of breast,It has important reference in mammary plastic surgery and mammary aesthetics,meanwhile,it also is an important anatomic landmark in breast surgery as well as an important metered reference point in the surgery of breast orthopaedics.

乳房下皱襞是乳房的一个重要结构,对于乳房美学以及乳房整形外科手术都具有重要参考价值。同时它也是乳房外科的重要解剖标志,是乳房整形外科手术测量的一个重要参考点。

Results: 1 The incidence rate of primary bilateral breast cancers was 2.5% with the morbidity age of 41 years, intermitting time between the two malignancies was 5.4 years. The 5-,10- and 20- year survival rates were 86.6%, 57.7% and 25.8% respectively. 2 The incidence rate of Paget′ s disease associated with breast cancer was 0.9% with a high incident age of 47.3 years and 5-, 10- and 20- year survival rates of 64.7%, 50% and 20.6% respectively. 3 The incidence rate of breast cancer associated with MPMNs of other organs was 3.6% with the peak incident age of 49.4 years, intermitting time of 8.6 years and the organs commonly involved were lung, uterus, esophagus, ovary and large intestine.

结果 :1双原发乳腺癌发生率为2.5%,发病年龄41岁,间隔时间5.4年。5、10、20年生存率分别为86.6%、57.7%和25.8%。2同一乳腺PD伴乳腺癌发病率为0.9%,高发年龄为 47.3岁。5、10、20年生存率为:64.7%、50%和20.6%。3乳腺癌伴其他脏器癌瘤的MPMNs发生率为3.6%,高发年龄 49.4岁,间隔时间为8.6年。

Intracystic carcinomas of the breast are rare entities that constitute 0.3% to 2.0% of all breast carcinomas, and the solid portion may be quite large at the time of diagnosis.3 We attempted to classify the types of sonographic findings of symptomatic cystic lesions of the breast and correlated these findings with the pathologic results.

乳腺的囊内癌是罕见的实体,占所有乳腺癌的0.3-2.0%,而且实性部份在诊断时已经较大[3]。我们尝试着根据超声特征和相关的病理结果将乳腺囊性病变进行分类。

This study intended to investigate the difference between breast tissues from juvenile macromastia patients and non-tumor invaded breast tissue taken from breast cancer patients, by analyzing mammary epithelial cell size.

器官的尺寸与细胞的尺寸及生长有关,因此本研究旨在量测青春期巨乳症病患乳房组织上皮细胞的尺寸,以厘清巨乳症成因与乳房上皮细胞尺寸的关系。

Patients who received reduction mammaplasty for juvenile macromastia in NTUH from January 2003 to December 2005 are enrolled as macromastia group. The control group includes the patients who received breast operation for breast cancer in NTUH in the same time period, with breast sizes not larger than C cup.

我们搜集西元2003年至2005年因青春期巨乳症而至台大医院接受缩乳手术且乳房尺寸大於等於E罩杯的病患为巨乳组,对照组则选取同一时期因乳癌於台大医院接受乳房切除手术且乳房尺寸小於等於C罩杯的病患,选取其未受乳癌侵犯的乳房组织。

Results: Breast pain: Thirty two women (60.4%) experienced cyclicpremenstrual mastalgia, lasting 4 days. Average serum 〓 level and serum progesteronelevel of women with cyclic breast pain in luteal phase were higher than that of womenwithout breast pain.

乳房胀疼者(41.3±45.9pg/ml)血清雌二醇水平明显高于无乳房胀疼者(18.5±20.6pg/ml),P<0.01.236名绝经后妇女中仍有12.5%(29/232)有乳房症状,其中75.9%(22/29)为绝经1-5年的绝经后妇女,乳房胀疼者(24.3±27.1pg/ml)与无乳房胀疼者(21.3±25.8pg/ml)的血清雌二醇没有显著差异,P>0.05。

Materials Methods: Beast ultrasound was performedduring luteal phase and late follicular phase in 50 women, aged 25~45, with normalmenstrual cycle and no distinct breast disease; Serum estradiol and progesteronelevel were measured by enzyme immunoassay on the day of ultrasound performed. Onehundred of twenty nine menopause transition women and 318 menopause women wereselected. All of them had ultrasound of breast and serum estradiol report. Breast pain wererecorded. Sixty menopausal women aged 56.8 yr. and menopausal aged 8.2 yr. participated1-year double-blind, randomized, placebo-controlled and 2mg 17β-estradiol continuouscombined with 1mg norethindrone acetate clinical study. Mastalgia was diaried. Breaststructure changes tested by high-resolution ultrasound at the 0 and 12 M.

资料和方法:征集身体健康,没有明显乳腺疾病的正常月经妇女53名,分别在月经的晚卵泡期和黄体期进行超声检查和测血清雌二醇和孕酮水平;收集有HRT前乳腺超声检查和血清雌二醇水平结果的绝经过渡期妇女129名和绝经后妇女318名,记录既往乳腺胀疼、过渡期乳腺胀疼、绝经后乳腺胀疼和既往乳腺病史。17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗和安慰剂随机双盲平行对照临床研究1年的60名参加者,分别在用药前后各进行一次乳腺超声检查,乳腺症状按同一表格由病人日记及经培训的一名医生定期随诊记录乳腺胀疼出现、消失的日期及持续的天数;超声检查用同一方法测量乳腺腺体层厚度、导管宽度、乳腺腺体结构及血流。

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