查询词典 bone

We show using in vitro and in vivo models that active TGF-beta1 released during bone resorption coordinates bone formation by inducing migration of bone marrow stromal cells, also known as bone mesenchymal stem cells, to the bone resorptive sites and that this process is mediated through a SMAD signaling pathway.

我们利用体外和体内模型，发现在骨吸收过程中释放的有活性的TGF-β1通过诱导骨髓基质细胞的迁移至骨重吸收位置来调节骨形成，这一过程通过SMAD信号途径调节。

Obvious cartilage and island-distributed immature bone formation in implants of the experiment side were observed at 2 weeks after operation, and massive mature bone observed at 4 weeks. Newly formed bone had fused and formed mature lamellar bone and trabecularism. No bone formation was observed in the control side of the mice.

实验侧术后2周出现大量软骨组织和呈岛状散在分布的骨组织，术后4周可见大量成骨组织，新生骨相互融合生长并形成较为成熟的板层骨和骨小梁结构；对照侧未见骨组织形成。

Transiliac bone biopsy showed highly increased bone mass (+63% versus age- and sex-matched controls), a decrease in bone remodeling without evidence of active osteoblasts, and a severe decrease in the dynamic parameters of bone formation (mineralizing surfaces,-90% and bone formation rate,-93% versus age- and sex-matched controls).

经髂骨的活检示骨量显著增加（与年龄和性别匹配的对照者相比增加了63％），骨重建降低且没有发现破骨细胞活化的证据（与年龄和性别匹配的对照者相比：矿化面-90%，骨形成率-90%）。

Results There was moderate or strong negative correlation among the indexes of the degeneration of intervertebral disc including the relative area of vascular bud, the ratio of the uncalcified and the calcified layer, the quantitation of collagen type Ⅱand the indexes of osteoporosis including the thickness ratio of cortical bone, the relative area of bone trabecula, the density of femoral bone and vertebral body bone, the max stress and straining of bone.

结果 骨质疏松相关指标骨皮质厚度指数、骨小梁相对面积、股骨密度、椎体骨密度与椎间盘退变指标终板血管芽相对面积、非钙化/钙化层比值、Ⅱ型胶原定量之间存在中度到强度的负相关，而与Ⅹ型胶原表达存在中度到强度的正相关，其中椎体骨密度与软骨终板的Ⅹ型胶原相关性最强。

Treatment of spinal tuberculosis1methods between february 1998 and august 2000 , 12 patients with spinal tuberculosis were operated with anterior vertebrectomy , bone grafting and plating1 evaluation including bone fusionrate , correction of deformity and status of spinal lesion was carried out1results in an average of ten months ,spinal tuberculosis was completely cured and solid bone fusion had taken place in all 12 patients1 the time for bone fusion averaged 518 months and the average angle of correction of kyphosis was 16°1conclusions anterior plating following vertebrectomy and bone grafting offers a complete removal of lesion and decompression of the spinal canal as well as reconstruction of spinal stability1 early rehabilitation and an increased curative rate can be expected through this procedure1

目的 探讨经脊柱前路结核病灶清除的同时植骨内固定的可行性和必要性，以及对脊柱结核的治疗效果。方法1998 年2月~2000 年8 月采用脊柱前路病椎切除加植骨，并采用orion或z-plate 钢板进行椎体固定。共治疗12 例脊柱结核，观察植骨融合及矫正畸形情况和结核病灶愈合情况。结果经平均10 个月的随访，12 例患者脊柱结核均治愈，植骨与受骨区全部骨性融合，融合时间平均为518 个月，后凸矫正角度平均16°。全组病例切口均一期愈合。无手术并发症。结论本方法可经脊柱前路作较彻底的病灶清除，并较好地进行脊柱矫形和椎管减压，完成脊柱稳定性重建，有利于患者早期离床活动和脊柱结核治愈率的提高。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质，术后免疫学、碱性磷酸酶、组织学检查发现：4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应，其中以新鲜骨移植引发的免疫反应最为显著；自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用，骨基质明胶对淋巴细胞增殖的抑制作用最显著；同种异体与同系4种植入物在体内成骨活性有显著差异；自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性，其中骨基质明胶骨诱导活性最佳。

This paper describes the method and results of the preparation of two palliating pharmaceuticals of bone pain resulting from bone metastatic carcinoma—〓Re-AEDP and 〓Ga-EDTMP, water-soluble fullerene derivatives which have affinity to bone, and pharmaceutical of bone metabolic diseases of bone— C〓-AEDP.

本文描述了转移性骨疼痛姑息治疗药物〓Re-AEDP、〓Ga-EDTMP、亲骨水溶性富勒烯衍生物及骨代谢性疾病治疗药物C〓-AEDP的研制。

To export whether the ovariectomy induced increase in bone resorbing activity present in supernatants fraction of bone marrow and the effects of endogeneous IL-6 on bone resorption, the bone resorbing activity present in marrow supernatants and the neutralizing effects of antibody against IL-6 were examined by the release of 〓Ca from perlabeled fetal rats parietal bone, the concentration of IL-6 were measured by Enzyme-Linked Immunosorbent Assay .

为了探讨卵巢切除是否导致骨髓上清骨吸收活性增加，以及白细胞介素-6在骨吸收中的作用，通过胎鼠颅骨〓释放实验测试骨髓上清的骨吸收活性及IL-6抗体的中和作用，通过ELISA测骨髓上清IL-6浓度。

Term bed can cause loss of bone mass and reduction of bone strength, which mainly ascribe to bone resorption. Salmon calcitonin can prevent the change of this kind.Key words: fracture; young; lying in bed; bone density; bone strength; salmon calcitionin

青壮年骨折病人长期卧床可引起骨量丢失、骨强度减低，主要由骨吸收引起，鲑鱼降钙素能预防该种骨量丢失与骨强度减低。

The technique of bone segment frifting is a simple and effective method for bone defect.Traumatic face of soft tissue can decrease and close,and the bone infection can be controlled gradually during the bone segment frift.Finally,the infection can be healed with the bone union.

结论骨段滑移技术是治疗下肢大段骨缺损简单而有效的方法，软组织感染创面可在骨段滑移中逐渐缩小并闭合，骨感染可在骨段滑移中逐渐被控制并随骨连接而愈合。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失