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Management of chronic osteomyelitis with a limb-salvage protocol consists of débridement, systemic and local antibiotic treatment, skeletal stabilization,soft-tissue coverage, and bone-grafting and/or reconstructive procedures for treatment of ununited fractures and existing bone defects.

骨折合并慢性骨髓炎保肢方案包括:清创,局部和全身抗生素治疗,骨折固定,软组织覆盖,骨移植和/或其他重建方案治疗骨不愈合及骨缺损。

Management of chronic osteomyelitis with a limb-salage protocol consists of débridement, systemic and local antibiotic treatment, skeletal stabilization,soft-tissue coerage, and bone-grafting and/or reconstructie procedures for treatment of ununited fractures and existing bone defects.

骨折合并慢性骨髓炎保肢方案包括:清创,局部和全身抗生素治疗,骨折固定,软组织覆盖,骨移植和/或其他重建方案治疗骨不愈合及骨缺损。

It can provide a stable and reliable fixation which is of benefit for early functional exercise. Bone grafting, closed reaming technique and knee joint adhesion release should be considered in order to enhance the bone healing and the improvement of knee ROM and function. Femoral fractures; Fracture fixation, intramedullary; Fractures, ununited

使用逆行交锁髓内钉治疗股骨远端骨折不愈合及延迟愈合具有固定可靠,便于膝关节早期功能锻炼等优点,但应联合行骨移植、闭合扩髓及膝关节粘连松解术,以促进骨折愈合,改善膝关节活动度和功能。

PDGF can modulate the functional balance between OB and OC directely or obliquely, and promote bone fracture healing and bone defect repairs, which is considered as a unwounded method that replaces some operations to treat such kind of patients.

PDGF直接或通过与其他生长因子的协同作用,调节成骨-破骨细胞之间的功能性平衡,加快骨折愈合和其他骨病损伤修复。如能实现和骨生物材料有机结合,有望使无创治疗代替有创手术,从而使此类患者减轻痛苦,缩短疗程。

To resolve the problem effectively, gene transfection technique is used in this experiment to transfer human VEGF into seed cells-mesenchymal stem cells of tissue engineer bone and to make it secrete VEGF which could vascularize bone.

国家自然科学基金资助课题(30471768/ C03030307)&组织工程材料栓塞颅内动脉瘤的实验研究&*;吉林省自然科学基金资助课题(2003053622)&转基因技术构建组织工程化颅骨修复材料的实验研究&

Typically, as people age, their bone mass decreases, making them more vuln erable to bone fractures.

通常当人们衰老的时候,他们的骨质减少,使他们容易骨折。

AIM To analyse the components of antigen-eliminated massive bovine cancellous bone and to study the mechanism of high concn H2O2 eliminating the antigenicity of xenogenic bone.

目的研究大块牛松质骨处理后的各种成分及高浓度H2O2消除异种骨抗原性的机制。

The present study has demonstrated the pattern of TNF-α and IL-6 expression, has defined the effect of cellular immunity on BMP-induced osteogenesis at the implant site, and has clarified the immunoregulation by BMP subsequent to bone xenografting, thus opening up a new field of molecular immunology associated with bone xenograft, allowing for the search for a more ideal approach to preventing immune rejection and developing a highly effective xenogenous graft material.

本研究结果揭示了异种骨移植局部TNF-α和IL-6的定位表达及其规律,基本上阐明了移植局部细胞免疫对BMP诱导成骨作用的影响及BMP在异种骨移植局部的免疫调节作用等问题,开辟了异种骨移植分子免疫学新领域,并为选择更理想的移植排斥防治途径和研制高效的异种骨移植材料提供了可靠的实验及理论依据。

Methods: The bone marrow cells were obtained from long bone of new born Zelanian rabbits, the cells were isolated and cultured in vitro in conditioned medium, then the acquired cells which had propagated in vitro and undergone frozen storage and resuscitation and gelatin sponge were made into a complex.

取新生新西兰大白兔四肢长管骨骨髓,分离后加入条件培养液体外培养,冻存复苏的细胞以明胶海绵吸附后回植于异体兔的桡骨缺损处作为实验侧,对侧以明胶海绵吸附生理盐水作为对照侧。

Osteoblasts isolated from the cranium of Zelanian rabbit,after being transfected with green fluorescent protein,were inoculated onto the bio-derived bone to investigate the 3D fabrication of engineering bone in rotating wall vessel bioreactor.

用经绿色荧光蛋白标记的新西兰兔颅骨来源的成骨细胞复合到生物衍生骨支架材料上,在新型旋转壁式生物反应器内三维构建组织工程骨,同时与静态培养环境中构建的结果进行比较。

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