查询词典 bone-boiling

Methods Marrow cells from NH mouse were harvested and cultured in α-MEM with 10% fetal bovine serum.The appearance of tartrate-resistant acid phosphatase-staining multinuclear cells and formation of bone resorption pits were measured after 3,6,9 and 12 day exposure to various concentrations of 1,25-2D3 in culture. Results 1,25-2D3 (concentration higher than 10-9mol/L) could induce recruitment of OLCs and their bone resorption activity in a dose-dependent manner.

收集NH小鼠骨髓细胞于含10%胎牛血清的α-MEM培养基中行体外培养，设置不同的1，25-2D3浓度组和给药时间组，并于培养第3、6、9、12天观察记录抗酒石酸酸性磷酸酶(tartrate-resistant acid phosphatase，TRAP)阳性多核巨细胞［或破骨细胞样细胞(osteroblast-like cell，OLC)］以及骨磨片上骨吸收陷窝的数目。

A line of osteoblasts is present a the center-right forming new bone, but lacunae containing multinucleate osteoclasts are at the center left and lower center destroying bone.

一行成骨细胞正在中右部形成新骨，而腔隙内的多核破骨细胞正在中左与中底部破坏骨。

The results showed that the cells had classic characteristics of osteoclasts: multinucleated giant cells, staining positively for TRAP in cells, forming bone absorptive lacunae on the bone slices.

结果表明，直接分离的细胞具有典型的破骨细胞的形态特点：属多核大细胞，TRAP染色阳性，能在骨片表面形成吸收陷窝。

Methods Applying 1,25-_2D_3 induced osteoclast-like multinucleated cells and isolated mature rabbit osteoclasts cocultured with bone slices, the effects of icariin on the differentiation and bone resorbing activity of osteoclasts were investigated.

方法采用1，25-2D3诱导兔骨髓单核细胞形成破骨细胞样细胞以及原代分离的乳兔成熟破骨细胞与骨片共培养的方法，考察淫羊藿苷对破骨细胞的分化及骨吸收功能的影响。

To investigate the morphological changes of megakaryocytes with nuclear extrusion and nucleocytoplasmic separation, the morphological characteristics of megakaryocytes in peripheral blood films, bone marrow smears, and bone marrow biopsies from 4 newly diagnosed patients with primary myelofibrosis, myelodysplastic syndrome, myeloblastic leukemia with maturation (M2) and erythroleukemia (M6) were studied by using light microscope.

为了观察巨核细胞逸核和胞核胞质连体分离的形态学变化，用光镜观察4例初诊血液病患者的血片、骨髓涂片和骨髓切片中巨核细胞形态特征。4例初诊血液病患者为1例原发性骨髓纤维化，1例骨髓增生异常综合征，1例急性粒细胞白血病部分成熟型(M2)和1例红白血病(M6)。

Results The pathology of all 10 cases of nasal lymphomas were T cell Non-Hodgkin's lymphoma, Ann Arbor stage Ⅰ～Ⅱin9 and 1 in stage IV. The locations of 10 lymphomae were in the anterior portion of one of the nasal cavities, and the lymphomae extended posteriorly along the inferior and/or media nasalis concha in different extent. No bone structure destruction was found in all stage I cases and the bone of the media nasalis concha as well as the uncinate process was partially absorbed in the stage IV nHL. The skin of the external noses adjacent to the lymphoma of the whole 10 cases were swollen in various severity with disappearance of the subcutaneous fat.

结果 10例鼻腔淋巴瘤病理均为T细胞非何杰金淋巴瘤，9例为Ann arbor I～II期，1例Ann Arbor IV期。10例病变均发生于一侧鼻腔前部，沿下鼻甲向后呈不同程度蔓延。9例I期病变均无骨质破坏，相邻鼻背侧皮肤不同程度肿胀，皮下脂肪消失，1例IV期病变可见患侧中鼻甲及钩突骨质部分吸收，同侧眶内肿瘤侵犯。

Results The main histopathologic changes were:① experimental group: inflammatory cell infiltration (1W); inflammatory cell disappearance, fibroblast and capillary tachyauxesis, osteoid tissue and small amount neoformative bone tissue appearance (2 W); fibrous tissue decrease, neoformative bone tissue enlarging and maturity (1～3 M).

结果① 实验组：术后1周，骨缺损区周围有炎性细胞浸润，可见牙槽骨变性坏死；术后2周，炎性渗出明显吸收，成纤维细胞、毛细血管生长活跃，可见骨样组织和少量骨组织；术后1～3个月，新生骨组织范围扩大，钙化程度加强。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th／Ts及Th1／Th2平衡紊乱，抑制大鼠PHφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

Abstract］ Objective To evaluate the clinical value of 99mTc-MDP breast and bone imaging detecting malignancy in breast neoplasma and early bone metastasis.

摘要］ 目的探讨99mTc-亚甲基二磷酸盐（99mTc-MDP）乳腺及全身骨显像对乳腺肿块良恶性的鉴别及早期发现骨转移的临床价值。

The reasons are probably that the micro-environment of cultivation is not perfect enough, engineered bone can not achieve the synchronization of vascularization and neurotization, and construction of the complex of tissue-engineered bone and periosteum is still lack of research.

可能的原因是细胞的培养微环境不够完善，没有实现组织工程骨的同步血管化和神经化，组织工程骨与骨膜复合体的构建目前仍缺乏研究。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。