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Blood were obtained for blood RT and plasma endotoxin concentration check. 6 All data underwent ANOVA analysis. Results: After 3hrs of LPS injection, 1 in hypermetabolic sepsis group, the average HR went to 334/min, the average body temperature went to 41.0℃, while in control group they were 274.9/min and 38.2℃ respectively. p=0.000, presented significant statistical differences. The average BP and breath rate in HS group were 97.1mmHg and 94.3/min , while they were 95.9mmHg and 76.4/min in control group, respectively presenting no statistical differences. 2 In HS group plasma endotoxin concentration was 0.088EU/ml while it was 0.013 EU/ml in control group presenting statistical significance, p=0.002. 3 Blood white cell ratio and total white cell counting were 82.73% and 1.90×109 in HS group, while they were 64.39% and 7.58×109 in control group presenting very significant statistical differences(p=0.001). There was no statistical significances in RBC counting and hemocrit between two groups.

结果:LPS持续灌注3h后,结果如下:1)高代谢脓毒症组的心率升高至334.0次/min、体温升高至41.0℃,而对照组则分别为274.9次/min和38.2℃,两组间有显著的统计学差异,p=0.000;血压在高代谢脓毒症组是97.1mmHg,而对照组为95.9mmHg,两组间无统计学差异;脓毒症组的呼吸加快至94.3次/min,对照组则提高至76.4次/min,两组间无统计学差异(p=0.212);2)其血浆内毒素含量为0.088EU/ml,而对照组为0.013 EU/ml,两组间有显著的统计学差异,p=0.002;3)血中性粒白细胞比值升高至82.73%,对照组则为64.39%,两组间有显著的统计学差异(P=0.001);白细胞总数则明显下降至1.90×109/ml,而对照组则为7.58×109/ml,p=0.001,两组间有显著的统计学差异;两组间的红细胞数及血细胞比容均无统计学差异。

Methods: The 80 four weeks old SD rats were divided into 8 groups at random.ie.normal group、physiological saline solution group、 Western medicine group、 angelica tonify the blood decoction group、 tonify the blood decoction add chalybeate group、 AS two solstices pill group、 AS two solstices pill add chalybeate group、AS two solstices pill add semi-dose chalybeate group.

4周龄SD大鼠80只,随机分成8组:即正常对照组、模型生理盐水组、西药组、当归补血汤组、当归补血汤加铁剂组、加味二至丸组、加味二至丸加铁剂组、加味二至丸加半量铁剂组。

Methods 104 patients with severe heart failure were divided into two groups. The control group was treated with routine treatment (digitalis,diuretic and distend the blood-vessel) combined with Imidapril (group A,n=52). The treatment group was treated with routine treatment (digitalis,diuretic and distend the blood-vessel) combined with Bisoprolol and Midapril (group B,n=52). The course of treatment was 12 to 16 weeks. Before and after treatment,the changes of heart function,LVEF,LVESD,heart rate and blood pressure were observed.

对104例重度心力衰竭患者随机分成两组:对照组52例,予以常规用药及咪达普利等药物治疗;治疗组52例,在常规用药基础上加用比索洛尔治疗,疗程12~16周,观察治疗前后心功能、左室射血分数、左室舒张末内径、左室收缩末内径、心率、血压等指标的变化。

Result The inhibitory effect on pulmonary metastasis of transplanted tumor were 46.36%, 32.73%, 18.2% in the Runing granule preparation group, warming kidney group, dispersing liver and promoting blood circulation group respectively. There wasn't significant difference between Runing granule preparation group and CTX group (50.91%). The expression of VEGF was dropped in Runing grannie preparation group and dispersing liver and promoting blood circulation group. The expression of TIMP-1mRNA was up-regulated in Runing Granule group and warming kidney group. The expression of MMP-9 was dropped in Runing granule preparation group and warming kidney group.

乳宁冲剂组及拆方温肾组、疏肝活血组对裸鼠乳腺癌移植瘤的肺转移抑制作用分别为46.36%、32.73%、18.2%,乳宁冲剂组作用与CTX组(50.91%)比较无显著差异;而乳宁冲剂组、疏肝活血组均可下调肿瘤VEGF蛋白表达;乳宁冲剂全方、温肾方可明显使TIMP-1mRNA的表达升高,MMP-9表达下降;对MMP-9/TIMP-1蛋白表达比值影响以温肾组下降最明显。

in order to probe into whether glycine supplementation plays an adjusting role in sports performance and immune functions, the authors divided 30 mice randomly into an exhaustive exercising group (e1), glycine supplemented exhaustive exercising group (e2) and a normal resting control group, with 10 mice in each group, supplemented glycine to mice in group e2 and physiological saline to mice in the other two groups, let mice in groups e1 and e2 do an exhaustive swimming exercise 4 weeks later, applied the trace ch50 hemolysis method to analyze supplement activity, applied the mtt method to perform a quantitative analysis on the lymphopoiesis ability of spleen, and thus revealed the following findings: compared with mice in group e1, the time taken by mice in group e2 to swim to an exhausted state is significantly longer (p.05); total supplement activity in blood serum of mice in group e1 is significantly lower than the same of mice in group s (p<0.01), and total supplement activity in blood serum of mice in group e2 is significantly higher than the same of mice in group e1 (p.01), but still significantly lower than the same of mice in group s (p.05); as observed from the test of the lymphopoiesis ability of spleen, the lymphopoiesis ability of spleen of mice in group e1 is significantly lower than the same of mice in group s, and the lymphopoiesis ability of spleen of mice in group e2 is significantly higher than the same of mice in group e1, but still significantly lower than the same of mice in group s.

四型肽精氨酸脱氨酶在类风湿性关节炎。。。以马来酸酐与氨水为原料热缩聚法合成。。。摘要:为探讨甘氨酸补充对运动能力及免疫功能是否具有调节作用,将30只小鼠随机分成力竭游泳运动组(e1)、甘氨酸补充后力竭游泳组(e2)和静息正常对照组,每组10只。在e2组补充甘氨酸,其余两组给予生理盐水,处理4周后,e1组和e2组均做力竭性游泳运动。采用微量ch50溶血法分析补体活性,采用mtt法定量分析脾脏淋巴细胞增殖能力。结果显示,与e1组比较,e2组游泳至力竭的时间显著延长(p<0.01)。e1组血清总补体活性显著低于s组(p<0.01),e2组显著高于e1组(p.01),但仍显著低于s组(p.05)。在脾脏淋巴细胞增殖试验中观察到,e1组显著低于s组,e2组显著高于e1组但仍显著低于s组。

objective:to approach the immunity status of pulse magnetic field treatment on treating paediatric lobular pneumonia.method:120 paediatric cases,suffering from lobular pneumonia by pulse magnetic field treatment,admitted by our department during the period of january 2008 and october 2008,designing observation group;120 cases,which were health check-up the same term,designing control group.observation group were picked blood 2ml before treatment and after treatment 4 weeks;control group was picked blood 2ml during health check-up.blood serum was separated and immunoglobulin was inspected by immunity nephelometry and immunity function were analyzed.results: iga igm igg value in 120 cases observation group was lower than of the control group and iga igm igg value was obviously heightener after treatment.the difference between the two cases was significant in statistics(p.05).conclusion: pulse magnetic field treatment on treating paediatric lobular pneumonia improve immunity function,boost up resistance of paediatric cases.

目的:探讨脉冲磁疗治疗小儿支气管肺炎前后体液免疫功能状况。方法:我科于2008年1月~2008年10月收治的部分支气管肺炎患儿采用脉冲磁疗治疗120例,设为观察组;同期门诊健康体检儿童120例,设为对照组,观察组于治疗前及治疗后4周分别采血2ml,对照组于体检时采血2ml,分离血清用免疫比浊法进行免疫球蛋白检测,并对治疗前后患儿的体液免疫功能进行分析研究。结果:120例观察组患儿治疗前iga igm igg值均低于正常对照组,且观察组治疗后iga igm igg值均较治疗前明显增高,且经统计学处理差异均有显著性(p.05)。结论:脉冲磁疗治疗小儿支气管肺炎改善了患儿的体液免疫功能,从根本上增强了抗病能力。

Abstract] objective to observe the effects of indapamide and losartan alone and combined treatment on the elder patients with hypertension,hypokalemia,hyperglycemia,uric acid,lipid,ect.methods one hundered and fifty patients with hypertension were randomly divided into three groups,with each of 50 cases.the levels of blood pressure,hypokalemia,blood sugar,uric acid,lipide were examined before and after treatment.results after 8 weeks the systolic and diastolic blood pressure were significantly lower.antihypertensive treatment group is the best,the levels of hypokalemia is lower after treatment in the indapamide group,the levels of uric acid is also lower in the losartan group and antihypertensive group.conclusion losartan and indapamide combined treatment not only coordinate to decrease blood pressure but also reduce uric acid,reduce the effect of hypokalemia caused by indapamide.

目的 观察氯沙坦与吲哒帕胺单独应用或联合用药对原发性高血压患者血压、血钾、血糖、尿酸、血脂的影响。方法将符合诊断标准的150例老年高血压患者电脑随机分为3组,每组50例,进行用药前后自身对照试验,8周后检测各组血压、血钾、血糖、尿酸、血脂值。结果 3组治疗后收缩压和舒张压均较前明显降低,联合治疗组降压幅度最大,氯沙坦组和联合治疗组治疗后尿酸值较治疗前降低,吲哒帕胺组治疗后血钾值较治疗前降低。结论氯沙坦与吲哒帕胺联合应用不仅具有协同降压作用,而且能降低尿酸,减轻吲哒帕胺引起的低钾血症。

objective we start with clinical research to explore the ability and mechanism of ion conduction with chinese herbs to curing ovulatory obstacle.methods adopting the methods of clinical observation random contrast.select the cases of ovulatory obstacle dividing randomly into two groups:therapeutic group and control group,the patients of therapeutic group using ion conduction with chinese herbs with act'on nourishing blood and promoting blood circulation to dissipate blood stasis when follicle grow up to 1.4cm.we take the decoction of jia jian tao hong si wu tang conducting the unilateral lower abdomen which has the dominant follicle,treating continuously for 4~8 days and observing ovulation.the patients of control group inject hcg 10000unit when follicle grow up to 1.8cm and observing ovulation.appraising two groups ovulated rate and pregnancy rate,and detect fsh、lh、e2、p at sixteen to eighteen days of menstrual cycle.results ion conduction with chinese herbs can significantly inspires ovulation and its effection is evidently higher than control group and has a higher pregnancy rate,no side effect of ovarian hyperstimulation syndrome.conclusion ion conduction with chinese herbs has significant function on inspiring ovulation.the target effection of treating ovulatory obstacle is exact.this method has a ovulated rate and higher pregnancy rate.

采用临床观察、随机对照的方法,选择排卵障碍的患者,随机分为治疗组和对照组,治疗组在b超监测卵泡生长达到1.6cm时,给予具有养血、活血化瘀作用的加减桃红四物汤水煎剂,用离子导入仪将中药水煎剂导入有优势卵泡的一侧少腹部,连续治疗4~8时天,同时连续监测卵泡排出情况。对照组在b超监测卵泡达到1.8cm时,开始采用hcg10000u肌注,连续b超监测卵泡排出情况。评价两组排卵率及受孕率,同时在月经周期的第16~22天抽血查fsh、lh、e2、p。结果运用离子导入的方法将具有促排卵作用的加减桃红四物汤水煎剂导入有优势卵泡的一侧附件,其促排卵的作用优于用hcg肌注促排卵,而且受孕率高,无卵巢过激综合征之虞。结论中药离子导入具有显著的促排卵作用,其治疗排卵障碍的靶向作用确切,排卵率及受孕率高。

Results: Compared with the C group, the contents of CORT in blood and ACTH in pituitary gland are increased at the different time points. Compared with the C group ,the contents of CR11 in Hypothalamus are enhanced in S and SAI groups on list but those are reduced in S and SM groups on 16st and 21st. Compared with the S group ,the contents of CORT in blood and ACH in pituitary gland are increased in SM group on 11 at. Compared with the SM groups, the contents of CORT in blood are reduced in TKXLD groups on 11st, l6st and 21st. Compared with the SAT group respectively, the contents of CRH in Hypothalamus are decreased in TKXLD group on list and those in TKXLD group are increased on 16st and 21st.

结果:实验第11、16和21天悬吊组和悬吊加辐射组大鼠血清CORT和垂体ACTH含量高于正常组;悬吊组和悬吊加辐射组大鼠下丘脑CRH含量在实验第11天高于正常组,在实验第16天和21天低于正常组;实验第11天悬吊加辐射组大鼠血清中CORT的含量高于悬吊组;实验第11、16和21天,中药组大鼠血清CORT含量低于悬吊加辐射组,垂体ACTH含量低于悬吊加辐射组;中药组大鼠下丘脑CRH含量在实验第11天低于悬吊加辐射组,在实验第16天和21天高于悬吊加辐射组。

Methods: To divide 102 patients with elderly hypertensive into 3 groups according to the difference of blood pressure result, and compare the relationship between serum uric acid and blood pressure among the different groups. They were divided into normal group、intimae tricking group、plaque shaping group and vascular stenosis group accoraing to ultrasound result. To compare the serum uric acid level and blood pressure among each group.

将102例老年高血压患者按血压值的不同分为三组,比较各组间血尿酸与血压的相关性,对各例患者分别检测血生化指标:空腹血糖、血尿酸、甘油三脂和总胆固醇,B超观察颈动脉变化,按B超结果将患者分为内膜正常组、内膜增厚组、斑块形成组和管腔狭窄组,比较各组间血压、血尿酸水平。

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