查询词典 blood cells

BACKGROUND: CD4+CD25+ T cells have low proliferation ability, and are about 4% of mononuclear cells in the peripheral blood.

背景：CD4+CD25+ T细胞增殖能力低，且在人外周血中仅占单个核细胞的4%左右。

Our study showed that about 3% mononucleated cells of human peripheral blood could be induced to osteoclast-like cells which have the ability of bone resorption and show TRAP-positive when coculture with UMR106 in the presence of 1,25 dihydroxyvitamin D3, macrophage-colony stimulating factor and dexamethasone.

在1，25_2D_3、地塞米松和M-CSF存在下，人外周血单个核细胞与UMR106细胞共培养，约3%的单个核细胞可被诱导成为具有骨吸收能力且抗酒石酸酸性磷酸酶染色阳性的破骨细胞样细胞。

Mononucleated cells were isolated by means of density gradient centrifugation from 20ml peripheral blood which collected from healthy normal donor. The mononucleated cells were planted on the glass coverships or bone slices and cocultured whith UMR 106 cell line, DMEM which contented 1,25 dihydroxyvitamin D3, M-CSF and dexamethasone was used as the culture medium.

从健康志愿者抽取外周静脉血，以密度梯度离心方法获得单个核细胞，在预先种植了UMR106细胞的盖玻片及骨片上，用含1，25_2D_3、地塞米松和M-CSF的DMEM培养液进行培养，而在未种植UMR106细胞的盖玻片上进行培养者作为对照组。

An HIV-1 strain, SH01, isolated by coculture of peripheral blood mononuclear cells was easily passaged in MT4 cell line and multinuclear giant syncytia could be induced in MT2 cells.

用外周血单个核细胞注意混合培养法分离到的HIV-1 SH01株，具有典型的HIV颗粒的形态学特征，核心颗粒呈锥形，可见芽生释放的全过程。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

To appraise effect of the home-made recombinant human granulocyte colony stimulating factor in the mobilization peripheral blood stem cells. From 2001 to 2005, 20 patients undergoing autologous peripheral blood stem cell transplantation were enrolled, 11 males, 9 females, 11 patients with acute myelocytic leukemia, 5 patients with acute lymphocyte leukemia, 3 patients with malignant lymphoma, and 1 patient with multiple myeloma.

为评估国产重组人粒细胞集落刺激因子在动员外周造血干细胞的效果，选择2001/2005收治的20例自体外周血造血干细胞移植患者，男11例，女9例，其中急性髓细胞白血病11例，急性淋巴细胞白血病5例，恶性淋巴瘤3例，多发性骨髓瘤1例。

However, this approach conferred the resistance to not only myelopoietic cells but also tumor cells that have invaded or metastasized into bone marrow or circulating blood for nonspecific expression of the exogenous genes.

详细骨髓造血细胞中导入耐药耐辐射基因是克服放化疗对造血系统抑制作用的有效手段，但外源基因的非特异性表达也增加了残存在血液或者侵犯至骨髓中的肿瘤细胞耐受性。

METHODS: Peripheral blood mononuclear cells from 33 AMI patients, 22 unstable angina patients and splenocytes from 35 AMI rats were collected. Cytokine-producing Th cells were monitored by 3-color flow cytometry after stimulated with phorbol myristate acetate and ionomycin.

采用流式细胞分析法对33例AMI病人，22例不稳定心绞痛病人和35例AMI大鼠进行Th细胞胞内干扰素γ和白介素4(IL-4)的动态监测，同时应用RT-PCR方法检测AMI大鼠心肌组织IFN-γ和IL-4以及T细胞表面趋化因子受体CCR3、CCR5和CXCR3 mRNA的表达。

The change of the control grouph histomorphology was clear: the inerassation of synovial lining cells, the infiltration of Inflammatory cells and the erosion of nephelium of blood vessels on bones.

模型组大鼠组织形态学改变明显：关节滑膜衬里层细胞明显增犀，炎性细胞浸润，血管翳组织侵蚀骨组织等；而给药组组织形态学改变显著减轻。

Results ① Normal morphological structure of brain microvascular endothelial cells and neuroglial cells were injured by 1,2-dichloroethane, which damaged blood-brain barrier.

结果］染毒后的脑微血管内皮细胞呈进行性破坏，随着染毒剂量的加大细胞体积逐渐增大，胞膜模糊，细胞与细胞间、细胞与突触间连接减少，甚至消失；随着染毒时间的延长，在10、30、60min后可以观察到有进行性的细胞膜溶解破坏，胞核模糊，界限不清，突触变短。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。