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Molecular detection in peripheral blood at surgery suggests that hematogenic tumor cell dissemination is a common and early event and that surgical manipulation enhances this release of tumor cells into the circulation.

血循环中癌细胞的存在是大肠癌的一种常见的早期事件,手术刺激可增加肿瘤细胞向血循环中释放。

This is the web page of Hematopoietic Stem Cell Laboratory, New York Blood Center.

这是纽约血液中心血液干细胞实验室的网页。

Objective:To explore the effect of different combination of hematopoietic cell growth factorson expanding umbilical cord blood hemopoietic cells in vitro.

目的:探讨造血细胞生长因子的不同组合对脐血CD34+造血干细胞的扩增作用。

MATERIALS: Re-sampled blood (5 mL) suspected as new gene from Chinese hemopoietic stem cell donators.

材料:中国造血干细胞捐献者初检结果可疑为新基因的重采血样5 mL。

Methods Granulocyte/macrophage colony stimulating factors and interleukin 4 were used to cultivate DC from peripheral blood of hepatocellular carcinoma patients.Tumor associated antigen extracted from human liver cancer HepG2 cell line was used to activate the DC,which will initiate homogenic T lymphocyte to form cytotoxic T lymphocyte.HepG2 cells were transplanted to the nude mice and were treated with CTL.Expression of PCNA in tumor cells was evaluated.

联合应用粒/巨细胞集落刺激因子及白介素-4(IL-4)直接从肝癌患者外周血中培养出DC;以源于人肝癌细胞系HepG2细胞的肿瘤抗原粗提物刺激DC;DC激活同源的T淋巴细胞产生细胞毒性T淋巴细胞;建立人肝癌细胞系HepG2裸鼠移植瘤模型;CTL治疗人肝癌细胞系HepG2裸鼠移植瘤;检测移植瘤标本肿瘤细胞PCNA表达水平。

RESULTS Pe-ripheral whole blood cells of this experimental rabbit re-duced,and by PCR,no donor's cell was found,and slight defective profileration of marrow occurred;the pathologic re-sults showed that its pathological processes mainly occurred in its skin and were all slighter than homogenic GVHD,and there was no obvious difference in the invaded regions be-tween heterogenic and homogenic GVHD.

结果 该实验兔外周全血细胞减少,PCR检查未发现供体细胞,骨髓轻度增生不良;病理结果显示其病变仍以皮肤为重但均较同种GVHD轻,其病变侵犯部位与同种GVHD无明显区别。

Viral replication and microbial translocation from the gut to the blood during HIV infection lead to hyperimmune activation, which contributes to the decline in CD4+ T cell numbers during HIV infection. Programmed death-1 (PD-1) and interleukin-10 (IL-10) are both upregulated during HIV infection.

加拿大蒙特利尔大学和美国佛罗里达免疫和基因治疗研究所的科学家合作进行的研究发现,膜蛋白PD-1和细胞衍生因子IL-10这两种分子联手作用,影响了艾滋病病人体内的CD4T细胞发挥正常作用,从而导致患者免疫系统受损并加快了患者病情的发展。

On closer scrutiny of the presenting blood count, despite normal haemoglobin and packed-cell volume,there was microcytosis with reduced mean corpuscular volume(74.5fL;NR 80-96fL)and hypochromia(mean corpuscular haemoglobin 23pg;NR 27-32pg).

对现有血细胞计数的详细分析,我们发现虽然有正常的红细胞计数和红细胞压积,但是存在平均血细胞体积减少(74.5fL;正常值范围 80-96fL)和血红蛋白减少(平均血红蛋白含量23pg;正常值范围 27-32pg

At the one-cell stage, each embryo was injected with gradient doses of 2-8ng MO. The control morpholino, was purchased from Gene-Tools.To test the knockdown effectiveness of the morpholino, the tbx2-EGFP (enhanced green fluorescent protein) construct was generated. And coinjection of morpholino with mRNA tests its specificity of the morpholino. Overexpression of tbx2 via mRNA microinjection helps us understand gaining function of tbx2. Results The tbx2-EGFP construct tests the knockdown effectiveness of the morpholino. Zebrafish embryos lacking tbx2 function have defects in cardiac contractility, rhythm and morphology in a dose-dependent manner. The embryos with c-MO are normal in development. Coinjection of morpholino with mRNA rescue the phenotype of tbx2 knocking down. The phenotypes include pericardial edema, hypogenetic ventricle, dilation of atria, arrhythmia, bradycardia, asystole, abnormal atrioventricular canal, aberrant valve and blood regurgitation.

结果荧光蛋白融合标记实验验证了tbx2-MO可以很好得阻抑斑马鱼胚胎tbx2的表达,tbx2-MO组胚胎在心脏收缩性、节律和形态学发生上出现了异常,心脏畸形随着注射剂量的增加而出现比较一致的表型,而c-MO组胚胎没有出现明显的畸形;tbx2-mRNA和tbx2-MO的共注射减少了tbx2-MO胚胎心脏畸形的发生率及减轻了心脏畸形的程度,验证了所设计合成的tbx2-MO对tbx2基因的抑制作用具有特异性;tbx2-MO组胚胎心脏缺陷包括心室发育不良、心房扩张、房室管和瓣膜异常以及心率缓慢、心律不齐、心脏停搏、血液返流等,并根据心脏发育异常的程度分为轻、中、重度畸形组tbx2-mRNA基因过表达胚胎没有见到心腔的形成。

METHODS: T-lymphocyte subsets and NK activity were determined by flow cytometry in 78 patients with hypopharyngeal squamous cell carcinoma. Blood samples of 20 non-tumor patients were used as control.

用流式细胞仪对78例喉咽鳞癌患者的外周血进行T淋巴细胞亚群及NK细胞活性的检测,并取20例非肿瘤患者的外周血作为对照组。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。