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Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%), 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%),Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%)恶性淋巴瘤症状, 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.

结果发生骨髓侵犯病例中I期4例(4.2%), II期12例(12.6%),Ⅲ期36例(37.9%)恶性淋巴瘤分期,Ⅳ期43例(47.4%);病理类型以小淋巴细胞性,弥漫型裂细胞性(改为:弥漫性大B细胞型淋巴瘤)和淋巴母细胞性淋巴瘤多见;纵隔淋巴结肿大、脾脏肿大和脾受侵患者易发生骨髓侵犯;骨髓侵犯患者外周血中贫血56例(58.9%),血小板减少42例(44.2%),白细胞减少27例(28.4%),白细胞增高49例(51.6%),以贫血多见;三项均异常30例(31.6%),至少一项不正常65例(68.4%),淋巴瘤细胞白血病患者外周血象异常发生率高于骨髓浸润患者,尤其是白细胞增高或三项均异常者更常见于白血病;66例(69.5%)外周血分类中发现异常细胞;骨髓侵犯化疗有效率65.2%,中位生存期11.5个月。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,"PMN-EC"相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Objective: To explore the effect of plasma exchange on graft-versus-host disease and pure red cell aplasia after allogeneic peripheral blood stem cell transplantation.

目的:探讨血浆置换治疗干细胞移植后移植物抗宿主病和纯红细胞再生障碍性贫血的疗效。

Element of 2 hydrogen arbutus contains many curative effect component, have the character of vitamin P, it can be passed reduce blood-vessel osmotic will protect blood-vessel to avoid with brittleness suffer harm, of this and berry tea fight oxidation function to concern, because because the cell is damaged by oxidation,hemal injury is,cause.

二氢杨梅素含有大量的疗效成份,具有维生素P的特性,它可通过降低血管渗透性和脆性来保护血管免受伤害,这与莓茶的抗氧化功能有关,因为血管的损伤是由于细胞被氧化损害引起的。

Shengyuan maintenance blood-sugar capsule is chooses the cactus, the balsam pear, the black bee bee glue, the kudzu root four pelts the sugar ingredient reasonably to blend, purifies the highly effective multi-skill health product by the modern biotechnology extract which but becomes, has the bidirectional adjustment, the control blood sugar, the activation and the nutrition island of langerhans beta cell, the promotion endogenous secretions insulin secretion, enhances the human body sugar metabolism and the fat metabolism ability, strengthens the pancreas function the function, at the same time also has the repair diabetes liver, the kidney damage, the prevention and the improvement diabetes illness complication function.

圣源维糖软胶囊是选择仙人掌、苦瓜、黑蜂蜂胶、葛根四大降糖成份合理配伍,以现代生物科技萃取精制而成的高效复合型健康产品,具有双向调节、控制血糖,激活和营养胰岛β细胞,促进内源性胰岛素分泌,提高人体糖代谢和脂肪代谢能力,增强胰脏功能的作用,同时又具有修复糖尿病肝、肾损伤,预防和改善糖尿病并发症的作用。

TS inhibition of T cell T-cell blood cells about 5% of the total to 10%.

抑制T细胞 TS细胞约占血液T细胞总数的5%~10%。

Methods The peripheral blood lymphocytes,sera of 55 patients with rheumatic carditis and a specific antigen from group A streptococcal cell membrane were prepared and used as stimulants to test the heart tissue cell procoagulant activity in culture.

用风湿性心脏炎患者的外周血淋巴细胞、血清及A组乙型溶血链球菌膜抗原作为刺激物,测定体外培养的人胚心肌细胞促凝血活性。

HPCA was measured by using a one-stage plasma recalcification clotting time.Results The peripheral blood lymphocytes from rheumatic carditis patients can stimulate the procoagulant activity of human heart tissue cell in vitro.But the sera of rheumatic carditis patients and group A streptococcal cell membrane can not increase HPCA.

结果 患者的外周血淋巴细胞能使HPCA明显升高;静止期风心病、风湿性关节炎、其他疾病对照组及健康对照组患者的外周血淋巴细胞均无此特性,迁延活动型风湿性心脏炎患者的血清及A组乙型溶血链球菌膜抗原对HPCA也无直接影响。

ABO blood gropu system Blood group incompatibility Stem cell transplantation Blood transfusion

ABO血型系统;血型不合;干细胞移植;输血

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