查询词典 blocked

Our results have shown that the analgesic effect of morphine administered to nucleus accumbens was blocked by intra-habenula injection of naloxone or ME antiserum, whereas the analgesic effect of morphine injected into habenula was attenuated by intra-PAG administration of naloxone or muscimol, and enhanced by bicuculline methochoride (BMC, an antagonist of GABA receptor).

本工作实验结果表明，在伏核内注射吗啡产生的镇痛作用可被缰核内注射NX或ME抗体所大部阻断，而缰核内注射吗啡产生的镇痛作用又可被PAG内注射NX或γ-氨基丁酸受体激动剂异鹅羔胺所削弱，被GABA受体阻断剂氯甲基荷包牡丹碱所增强。

Thus, the analgesic effect of morphine injected into PAG was significantly attenuated by β-EP AS injected into the nucleus accumbens, and vice versa. This antagonistic effect was totally abolished by lesioning of the ARH. Moreover the analgesic effect of morphine injected into nucleus accumbens could be blocked byβ-EP AS administered te amygdala or habenula.

在PAG内注射吗啡产生的镇痛作用可被伏核内注射β-EP抗体所削弱，损毁家兔的ARH后这一对抗效应基本消失；在伏核内注射吗啡产生的镇痛作用可被PAG内注射β-EP抗体所对抗，损毁ARH后上述对抗效应基本消失；伏核内注射吗啡产生的镇痛作用亦可被杏仁核内或缰核内注射β-EP抗体所阻断。

Later, he visited the central Afghanistan region of Hazarajat, documenting the famine that arose when Northern Alliance forces blocked food deliveries to the ethnic Hazara people – whom they accused of collaborating with the Taliban – and because UN aid could rarely get through to the mountainous region.

不久后他来到阿富汗的中部地区哈扎拉贾特（哈扎拉人是成吉思汗的后裔。17世纪，阿富汗中部的哈扎拉地区被波斯湾帝国占领。

Methods Hepatoduodenal ligament was blocked under normal temperature and aseptic condition in rabbits model to lead to an intestinal anoxia and damage of intestinal mucosa barrier, and then a great quantity of endotoxin would enter portal vein through intestinal wall resulting in endotoxinemia.

采用兔做动物模型，在常温无菌条件下机械性阻断肝十二指肠韧带造成肠道缺血、缺氧、肠黏膜屏障损害，肠道内大量内毒素穿过肠壁进入门静脉，造成内毒素血症。

MB (10 μ mol/L), an inhibitor of GC, not only blocked completely the relaxation of HIMA, but also enhanced the vascular contraction induced by norepinephrine.

MB是GC的抑制剂， 10 μ mol/L的MB不但使VNP舒张HIMA的作用完全消失，而且可增强HIMA对去甲肾上腺素产生的收缩反应。

If the tubes are blocked, the liquid will be trapped and your doctor will be able to tell that you have a hydrosalpinx.

如果输卵管堵塞，液体会滞留，医生就能判断你输卵管积水。

Methods analyzed the 60 cases of patients whom were conducted salpingography with tubal patent test apparatus by liquid instillation.results in 60 cases, both oviduct get through in 42 cases , account for 70%;one oviduct incompletely get through in 6 cases, account for 10%;both oviduct were blocked in 12 cases, account for 20%.among them ,2 cases of hydrosalpinx ,4 cases of ampulla of uterine tube obstruction,6 cases of scarcity in one side oviduct,10 cases of absence of develop in interstitial portion of the tube.

分析研究60例子宫输卵管造影患者应用输卵管通液诊疗仪进行检查的病例资料。结果：60例中，双侧通畅者42例，占70%；一侧通而不畅者6例，占10%；双侧输卵管不通者12例，占20%。其中2条输卵管伞端积水；4条输卵管壶腹部阻塞，6条输卵管一侧缺如。10条输卵管间质部不显影。

Intrathecal injection of nonselective opioid antagonist naloxone blocked the OT-induced antinociception in normal rats and in rats with inflammation; intrathecal injecion of naloxone lightly enhanced the OT-induced hyperalgesic effect in rats with ligation during hyperalgesia phase.

在正常和炎症痛大鼠鞘内注射naloxone几乎完全阻断催产素的镇痛作用，在神经损伤性痛大鼠中naloxone轻微增强催产素的痛敏作用。

Lose weight, poor health, partly numb, cold hand and feet, hyperhidrosis, have a pain in the back, easy to get cold, herpes on the mouth, blocked or watery nose, dysphoria, insomnia or hypersomnia, hypodynamia, lose hair, speckle face and allergy.

体重减轻、体虚力单、局部麻木、手脚易冷、掌腋多汗、腰酸背痛；易患感冒、唇起疱疹、鼻塞流涕、烦躁不安、易患失眠或嗜睡；四肢乏力、指甲成像、脱发、面部褐斑及过敏体质

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。