查询词典 block signal

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

ERCS can inhibti intracellular signal transudation of PDGF in HSC to block the biological effect of PDGF.

莪术提取物药物血清能抑制PDGF诱导的肝星状细胞内Ca(上标 2+)内流及PI3-K的表达。

On the base of them, LabVIEW block diagrams and front panels of several main models of electric parameter test are designed.At the same time,the hardware structure of test system is studed,and hardwares such as the data acquisition and signal conditioning circuit and so on are designed.

在此基础上设计出了五个主要电气参数测试模块的虚拟仪器程序框图和前面板，同时研究了测试系统的硬件组成，设计出了数据采集以及信号调理电路等硬件。

Take the video signal as the carrier, the sender choice embedding the hiding information in the DCT coefficient, according to neighboring many DCT block DC coefficient size relations,, embedding control code, Control information correct extraction.

以视频信号为载体，发送方选择在DCT系数中随时嵌入隐藏信息，根据相邻多个DCT块的DC系数的大小关系，嵌入控制码，控制信息正确提取。

By ultrasonic echo noise-reduction testing on CS-1-5 test block's flat bottom hole and certain helicopter totors' fatigue flaw, it is shown that ultrasonic signal SNR is increased remarkably.

经对CS-1-5试块的Φ2平底孔超声反射回波和某型直升机旋翼大梁疲劳裂纹超声反射回波的降噪试验，试验结果表明，处理后的超声信号信噪比显著增强。

The utility model has the advantages of novel structure, fixing the load transducer on the glide cushion block of the hydraulic rope adjusting device of the wire rope of the elevator, directly reflecting the actual load of wire rope and ensuring the authenticity, reliability and stability of the signal of the transducer.

优点在于：结构新颖，将载荷传感器固定在提升机钢丝绳液压调绳装置的滑动垫块上，能直接反映钢丝绳的实际载荷，保证了传感器信号的真实性及其工作的稳定性和可靠性。

To settle down this practice problem theoretically, this paper focuses on the research of signal coordination of mid-block street crossing and intersection.

为了更好地解决这一实际问题，本文对路段行人过街信号与交叉口信号的协调控制方法进行了研究。

Introducing mixed-crossing horizontal-influence reducing coefficient, the paper modified the capacity formula of mid-block street crossing, and put forward pedestrian cross-street green time formula on condition of signal control.

引入了混合过街横向影响折减系数，对人行横道通行能力计算公式进行修正，并提出了人行横道信号控制方式下行人过街绿灯时间的计算公式。

The results showed that over 500.0 μg/L of Jagged-1/Fc led to the obvious enhancement of the proportion of CD4+CD25+ T cells within the day 4 to 6 of induction, which was abrogated with an anti-Jagged-1/Fc monoclonal antibody. This induction action of Jagged-1/Fc on CD4+CD25+ T cells was also inhibited by the block of a Notch signal pathway with N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester. The level of IL-4 and IL-10 in the supernatant of T cell culture and their intracellular level were elevated by the induction of Jagged-1/Fc,and the level of TGF-β1 in the supernatant was not altered.

结果显示，超过500.0 μg/L剂量的Jagged-1/Fc使CD4+CD25+ T细胞百分比明显增高，诱导时间需要4～6天，抗Jagged-1单抗能抵消Jagged-1/Fc的诱导作用，用DAPT阻断Notch信号通路的活化也能抑制Jagged-1/Fc的诱导作用，Jagged-1/Fc诱导分化的T细胞培养上清中IL-4和IL-10的水平明显增高，TGF-β1无明显变化，胞内IL-4，IL-10，IL-2和TNF-α的水平也呈增高趋势。

Self-checking is an indispensable function in remote testing matching device. So doing research on high precision signal block is one of the most important parts of the device.

1引言在导弹型号的研制过程中，匹配装置是用于遥测系统中信号变换的关键部件，是弹上所有关键部件的信息送到遥测设备的咽喉。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。