查询词典 bile

PSC is a kind of rare and unknown disease due to stenosis cholangitis.Its main symptoms is diffuse fibrotic incrassation and duct stenosis in intrahepatic and extrahepatic bile duct system..

原发性硬化性胆管炎（ primary sclerosing cholangitis，PSC ）是一种少见的、原因未明的胆管炎症性狭窄性疾病。

Methods The antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

采用干酵母、2，4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用；采用胆管引流法分别收集并计量给药后0.5，1，1.5，2 ，2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响；采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响；对SMPS进行了小鼠急性毒性实验。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

目的研究玉米须多糖的清热利胆作用及急性毒性。方法采用干酵母、2，4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用；采用胆管引流法分别收集并计量给药后0.5，1，1.5，2 ，2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响；采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响；对SMPS进行了小鼠急性毒性实验。

MethodsThe antipyretic activity of SMPS was observed in rats with high temperature induced by dried yeast and 2,4-dinitrophenol; biliary duct cannula bile at 0.5,1,1.5,2,2.5 h after intraduodenal administration in rats was collected and counted to observe the effect of SMPS on biliary secretion;the weight of cholecyst in mice was counted to observe the effect of SMPS on the cholecyst of mice;the acute toxicity test of SMPS was done with mice.

方法采用干酵母、2，4二硝基苯酚致大鼠发热的模型观察玉米须多糖的解热作用；采用胆管引流法分别收集并计量给药后0.5，1，1.5，2 ，2.5 h的胆汁的方法观察SMPS对肝脏分泌胆汁的影响；采用测定小鼠胆囊重量的方法观察SMPS对胆囊的影响；对SMPS进行了小鼠急性毒性实验。

In some concentration,bile reflux affect little on the intragastric pH.

在一定浓度下，胆汁反流对胃内pH值影响较小。

Results In the 260 slices of liver biopsy, there were 20 ones of acute viral hepatitis, 78 ones of chronic hepatitis, 79 ones of hepatocirrhosis, 28 ones of primary liver cell cancer, 27 ones of liver karyon heterogeneity, 20 ones of liver metastatic adenocarcinoma, 12 ones of fatty liver, five ones of alcohol liver, three ones of liver cyst, two ones of congenital bile duct atresia, six ones of illegible structure, 20 ones without liver cell or with few scattered liver cell.

结果 260例肝穿活检组织病例中，急性肝炎20例；慢性肝炎78例；肝硬化39例；原发性肝细胞癌28例；肝细胞核异质27例；肝转移性腺癌20例；脂肪肝12例；乙醇肝5例；肝囊肿3例；先天性胆管闭锁2例；穿刺组织结构模糊6例；未穿到或仅穿到少量肝细胞20例。

Results 20 cases of CT examination had made proper diagnoses,the CT imaging finding about the most of peripheral cholangiocarcinoma included:There was the atactic low density tumour in liver,its borderline was unclear,enhanced scan appearances were irregular peripheral enhancement,centripetal enhancement,and delaying enhancement;There was concretion and dilatation of bile buct in or around the focus;The local envelope of liver was lacunose and the local liver was atrophied,There was abroad putrescence and liquescence in the focus.

结果 20例CT做出了正确的诊断，部分周围型胆管细胞癌的CT表现肝内不规则低密度肿块边界欠清，增强扫描表现病灶边缘呈不规则环状强化，有向心性强化的趋势，出现延迟强化；病灶内或周围可见结石，病灶内及周围肝内胆管扩张；局部肝包膜回缩、肝叶萎缩，病灶内大片坏死、液化。

So thisexperiment ligate bile duct partly of rats and assure normal liver tissue and abnormalliver tissue concurrence.

所以这次研究采用部分大鼠肝脏胆管结扎，保证同时有病变及正常肝组织。

In addition, SW480 and HCT116 cells were treated with deoxycholic acid for 15, 30, 45, 60, 90 and 120 minutes. It was found that the deoxycholic acid treated cells showed an elevation of ATP activity by 12.35 %, 20.08 %, 29.69 %, 33.56 %, 45.85 %, 54.32 %, respectively. While the HCT116 treated cells, showed an elevation of ATP activity by 3.69 %, 5.59 %, 8.52 %, 12.26 %, 16.52 %, 19.71%, respectively.From the experiments conducted using the cell lines described above, it was further confirmed that genes CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1), AKR1D1 (aldo-keto reductase family 1, member D1), ALDH1A1 (aldehyde dehydrogenase 1 family, member A1), BAAT (bile acid Coenzyme A: amino acid N-acyltransferase), ABCA1 (ATP-binding cassette, sub-family A, member 1), APOC3 (apolipoprotein C-III), LIPA, LIPE (lipase, hormone-sensitive), PTGER2 (prostaglandin E receptor 2) and PTGS2 (prostaglandin-endoperoxide synthase 2) were up-regulated.

此外，为了证实其脂肪代谢产物胆酸对细胞癌化的影响，亦使用SW480和HCT116细胞株，经由脱氧胆酸在15分钟、30分钟、45分钟、60分钟、90分钟和120分钟处理后，其细胞增生比率分别有12.35%，20.08%，29.69%，33.56%，45.85%和54.32%(p.05)以及3.69%，5.59%，8.52%，12.26%，16.52%和19.71%(p.05)上升情形，并从这些细胞株进一步证实CYP7A1(细胞色素P450-7A1)、AKR1D1(醇醛酮还原酶-1-D1)、ALDH1A1(醛脱氢酶-1-A1)、BAAT(胆酸辅酶A：氨基酸N-醯基转移酶)、ABCA1(三磷酸腺苷结合盒转运体A1)、APOC3、LIPA、LIPE(脂肪酶/激素敏感脂肪酶)、PTGER2(前列腺素E受体2)和PTGS2(前列腺素内过氧化物合成酶2)等基因表现皆有呈现向上调控的情形。

Lithogenous diet caused liver damage, then abnormality of metabolism of bile acids, and promoted gallstone formation.

致石食物首先引起肝脏病理损害，继而导致胆汁代谢紊乱，尤其是胆汁酸代谢紊乱，促使了胆结石的形成。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。