查询词典 bile acid

Cholesterol gallstones formed in C57L mice and fatty livers developed in AKR mice. Conclusions Biliary cholesterol hypersecretion is the key pathophysiological defect of gallstone formation, lith genes have effects on biliary cholesterol hypersecretion and susceptibility to cholesterol gallstone formation in C57L mice. Lithogenic bile is formed at the canalicular membrane and precedes the development of cholesterol gallstones. It is most likely that cholesterol and bile acid hyposecretion make the AKR strain susceptible to the development of fatty livers and resistant to gallstone formation.

结论胆道胆固醇的高分泌是胆囊胆固醇结石形成的主要病理生理基础，结石基因决定了C57L鼠肝内胆汁中胆固醇的高分泌和胆囊胆固醇结石的易患性，成石胆汁形成在肝内胆管，先于胆囊结石的形成；肝内胆汁中胆固醇和胆酸的低分泌可能与AKR鼠脂肪肝的发生和胆囊结石的免患性有关。

A series of novel bile acid derivatives as potential hepato-biliary and intestinal scintigraphy imaging SPECT (single photon emission computed tomography) tracers were prepared from bile acids by es-terification, aminolysis of esters and alkylation of amino groups.

以胆酸、鹅去氧胆酸为起始原料，经羧基的酯化、酯的胺解以及氨基的烷基化，合成了一系列潜在的针对肝胆显像和肠显像的SPECT (Single photon emission computed tomography)分子探针前体。

People's bile acid are cholic acid and the goose desoxy cholic acid.

如人的胆汁酸是以胆酸、鹅脱氧胆酸为主，而奶牛胆汁酸的主要成分为胆酸和脱氧胆酸，鸡体内脱氧胆酸含量很少，鹅脱氧胆酸的含量最高。

The bile acid,phosphoˉlipid and cholesterol in the bile of gallbladder were analyzed by chromatograph of liquid and the gallbladder was examined by both light and electron icroscope.Results At the end of the6 th week,none of the group N had gallstone.

饲养6周后处死观察胆囊结石形成情况，测定胆囊胆汁中胆汁酸、磷酸、胆固醇，观察胆囊超微结构的变化以及糖尿病模型的胰腺病理改。

Killed at the end of the6 th weeks of fedding,the condition of stone formation in the gallbladder was observed.The bile acid,phosphoˉlipid and cholesterol in the bile of gallbladder were analyzed by chromatograph of liquid and the gallbladder was examined by both light and electron icroscope.

饲养6周后处死观察胆囊结石形成情况，测定胆囊胆汁中胆汁酸、磷酸、胆固醇，观察胆囊超微结构的变化以及糖尿病模型的胰腺病理改。

IntroductionSmooth surfaced endoplasmic reticula contain plenty of cyto-chromes, which are mainly cytochrome P450 ( CYP450 ) and b5 and are very important in the process of the biotransformation of exogenetical fat - soluble compounds and the metabolism of some endogenetical matrices, such as bile acid forming^ bile pigment metabolism and steroid synthesis.

CYP450是50年代中期Williams和Klingeberg发现、60年代初木村和佐藤验证的一类b族细胞色素，由于还原型细胞色素与一氧化碳结合后在光谱的450nm处具有最高吸收峰，因而命名为CYP450以别与其它b族细胞色素，P是英文Peak的缩写。

Approximately some 1/4 unio primary bile acid in the jejunum,the ileum and the colon upside ,with the effect of enzyme's catalysis,produces the deoxycholic acid,the lithocholic acid ,the bear deoxycholic acid and etc.

大约有1/4的结合型初级胆汁酸在空肠、回肠及结肠上段，在细菌的酶的催化下，进一步生成去氧胆酸、石胆酸、熊去氧胆酸等次级胆汁酸。C·胆汁酸的合成：肝细胞合成的胆汁酸与甘氨酸或牛磺酸结合，形成结合型胆汁酸，分泌入胆道。

The PVA without limiting the blood flow volume can increase the cross section and blood flow volume of portal vein ,dilate and thicken the branches of portal vein, but the function of reticuloendothelial system, metabolism of bile pigment and bile acid salt don′t undergo significant influences.

未采取限流措施的门静脉动脉化可导致门静脉横截面积和血流量增加，门静脉分支扩张、管壁增厚，但网状内皮系统的吞噬功能以及胆色素和胆盐的代谢未受显著的影响。

Results Bile flow, serum levels of total bile acid and gamma glutamyl transpe...

而给予SAMe的Ⅲ、Ⅴ组胆汁流升高，血清总胆酸和γ GT水平明显降低，肝脏病理结果正常、毛细胆管不扩张、无胆栓；临床 16例患者给药前表现为胆汁瘀积和肝功能损害，给予SAMe 3周后血总胆红素、碱性磷酸酶、γ GT、谷丙转氨酶、谷草转氨酶均较给药前的异常水平有显著下降，第 4周恢复至正常水平。

AIM: To analyze the changes of the total bile acid and the ratio of cholic acid/chenodeoxycholic acid in serum of patients when rejection reaction and the transplanted liver functional recovery delay happen after liver transplantation.

目的：评价肝移植术后患者血清总胆汁酸水平、胆酸，鹅脱氧胆酸比值在肝移植术后发生排斥反应及肝功能延迟恢复时的变化规律。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。