查询词典 bile acid

Results Bile acid metabolites were different between the patients and the healthy controls, even the dead patients and the cured patients. On the fourth day of consuming amanita verna, the bile acid metabolites of the dead patients were markedly different from those of the cured patients.

结果 白毒伞中毒患者的胆汁酸代谢产物与健康对照组有很大差异；死亡患者与治愈患者的胆汁酸代谢产物也不相同；二者之间的差异在食后第4天就明显地表现出来。

But after bile salt stimulation, total bile acid and glutathione concentration in bile were significantly increased in AQP8 null mice compared with wild type mice.

本课题利用AQP8和AQP1基因敲除小鼠模型，系统地研究了水通道蛋白AQP8和AQP1在小鼠"原始"胆汁的形成和胆囊内胆汁浓缩过程中的作用。

Glycocholic acid is a kind of glycol-conjugated bile acid which exists in many animals'bile. It is one of main component of bile acid and was synthesized from cholalic acid and glycine in liver.

甘氨胆酸是胆汁酸的主要成分之一，属于结合型胆汁酸，在肝脏中由胆酸和甘氨酸结合而成。

The free bile acid and dihydroxy bile acid glycine union(exisistence by the of non-ionic form ) also be absorb again through the simple proliferation way.this may occurs in any part of the small intestine and colon.

未结合的胆汁酸和二羟基胆汁酸的甘氨酸结合物，也过简单扩散的方式被重吸收。这种通过小肠膜的非离子化扩散可在小肠的任何部位及结肠发生。

The mean conˉcentrationsof the total bile acid in the gallbladders were respectively77.53±11.93,51.81±8.12and53.27±7.04in group DM,CH and DMCH,but it was79.28±18.28in group N.Combined bile acids（both glycocholic acid and taurocholic acid）were apparently lessened and the ratio of cholic acid and chenodeoxycholic acid was rised in group DM,CH and DMCH,the concentrationsof cholesterol were respectively5.31±0.81,5.69±2.20and5.12±1.47,but0.86±0.20,in the group N;those of phospholipd were respectively0.35±0.16,0.52±0.18and1.38±0.34,but0.59±0.28,group N.

胆囊胆汁成分分析中，DM组、CH组和DMCH组总胆汁酸分别为77.53±11.93、51.81±8.12和53.27±7.04，N组为79.28±18.28；与N组比较结合胆汁酸减少，其中甘氨胆汁酸盐与牛磺胆汁酸盐均减少；鹅去氧胆酸减少，胆酸/鹅去氧胆酸比值升高；胆汁胆固醇分别为5.31±0.81、5.69.20和5.12±1.47，N组为0.86±0.20；磷脂分别为0.35±0.16、0.52±0.18和1.38±0.34。

Stones were seen in the gallbladder of12/12cases in either group DM and CH,and11/12in the group DMCH.The mean conˉcentrationsof the total bile acid in the gallbladders were respectively77.53±11.93,51.81±8.12and53.27±7.04in group DM,CH and DMCH,but it was79.28±18.28in group N.Combined bile acids（both glycocholic acid and taurocholic acid）were apparently lessened and the ratio of cholic acid and chenodeoxycholic acid was rised in group DM,CH and DMCH,the concentrationsof cholesterol were respectively5.31±0.81,5.69±2.20and5.12±1.47,but0.86±0.20,in the group N;those of phospholipd were respectively0.35±0.16,0.52±0.18and1.38±0.34,but0.59±0.28,group N.

胆囊胆汁成分分析中，DM组、CH组和DMCH组总胆汁酸分别为77.53±11.93、51.81±8.12和53.27±7.04，N组为79.28±18.28；与N组比较结合胆汁酸减少，其中甘氨胆汁酸盐与牛磺胆汁酸盐均减少；鹅去氧胆酸减少，胆酸/鹅去氧胆酸比值升高；胆汁胆固醇分别为5.31±0.81、5.69.20和5.12±1.47，N组为0.86±0.20；磷脂分别为0.35±0.16、0.52±0.18和1.38±0.34。

In addition, SW480 and HCT116 cells were treated with deoxycholic acid for 15, 30, 45, 60, 90 and 120 minutes. It was found that the deoxycholic acid treated cells showed an elevation of ATP activity by 12.35 %, 20.08 %, 29.69 %, 33.56 %, 45.85 %, 54.32 %, respectively. While the HCT116 treated cells, showed an elevation of ATP activity by 3.69 %, 5.59 %, 8.52 %, 12.26 %, 16.52 %, 19.71%, respectively.From the experiments conducted using the cell lines described above, it was further confirmed that genes CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1), AKR1D1 (aldo-keto reductase family 1, member D1), ALDH1A1 (aldehyde dehydrogenase 1 family, member A1), BAAT (bile acid Coenzyme A: amino acid N-acyltransferase), ABCA1 (ATP-binding cassette, sub-family A, member 1), APOC3 (apolipoprotein C-III), LIPA, LIPE (lipase, hormone-sensitive), PTGER2 (prostaglandin E receptor 2) and PTGS2 (prostaglandin-endoperoxide synthase 2) were up-regulated.

此外，为了证实其脂肪代谢产物胆酸对细胞癌化的影响，亦使用SW480和HCT116细胞株，经由脱氧胆酸在15分钟、30分钟、45分钟、60分钟、90分钟和120分钟处理后，其细胞增生比率分别有12.35%，20.08%，29.69%，33.56%，45.85%和54.32%(p.05)以及3.69%，5.59%，8.52%，12.26%，16.52%和19.71%(p.05)上升情形，并从这些细胞株进一步证实CYP7A1(细胞色素P450-7A1)、AKR1D1(醇醛酮还原酶-1-D1)、ALDH1A1(醛脱氢酶-1-A1)、BAAT(胆酸辅酶A：氨基酸N-醯基转移酶)、ABCA1(三磷酸腺苷结合盒转运体A1)、APOC3、LIPA、LIPE(脂肪酶/激素敏感脂肪酶)、PTGER2(前列腺素E受体2)和PTGS2(前列腺素内过氧化物合成酶2)等基因表现皆有呈现向上调控的情形。

The duodenal juice mainly consists of the bile acid, which is a sort of lipophilic steroid and may result in direct injuries of mucosal epithelial cells and their tight junctions. Some researches have showed that the bile acid directly damaged the chemical environment of mucosa surface and played a synergistical role in gastric mucosal lesions along with gastric acid and H.

十二指肠反流液中主要成分为胆汁酸，胆汁酸是十二指肠反流液中造成黏膜损伤的主要成分，为一种亲脂性类固醇，直接破坏黏膜上皮细胞以及细胞间的紧密连接，同时还对腔内及黏膜表面的化学环境造成直接的影响，增强胃酸、H。

Taurocholic Acid is a kind of tauro-conjugated bile acid which exists in many kinds of animals' bile.

牛磺胆酸(Taurocholate acid， TCA)是存在于多种动物胆汁中的一种结合型胆汁酸。

When the swine's bile acid, made from the waste liquid of swine's bile after bilirubin is extracted, is used as an antitussive medicine to treat the mice's cough induced by SO2 the following result is recorded: The swine's bile acid is effective in prolongating the cough latency and decreasing the cough frequency per unit time.

本文利用提取胆红素后的猪胆汁废液所制备的猪胆汁酸，作对SO_2诱发咳嗽的正常NIH系小白鼠镇咳效果观察。结果表明；猪胆汁中的胆汁酸对SO_2诱发咳嗽的小白鼠具有延长诱发咳嗽潜伏期和减少单位时间内咳嗽次数的效果。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。