查询词典 bicyclic

A simple connected graph is called bicyclic if it has n vertices and n + 1 edges.

双圈图是指边数等于顶点数加1的简单连通图。

In China an eight-step approach to the cis-bicyclic amine was adopted, including five-step route to cyclopentane-...

国内工业生产方法是以环己酮为原料经五步反应合成中间体1，2-环戊烷二甲酸，再经过三步反应完成顺式构型的建立和氮杂五元环的合成。

At the same time several fused bicyclic heteroatom analogs were synthesized. Some of our Smac mimetics promote apoptosis in cancer cells.

与此同时，我们还合成了一些杂原子取代的并环Smac模拟物并测试其生物活性。

From the calculations, it can be found that the van der Waals interactions, the hydrophobic interactions, as well as the H-bonding interactions are crucial for the ligand binding. The 4-phenylamino group can produce strong van der Waals adn hydrophobic interactions with the nonpolar side chains of the residues deep in the binding cleft. The R^1 and R^2 substituents on the bicyclic chromophore can also produce strong van der Waals and hydrophobic interactions with the residues located at the exterior part of the binding pocket. Moreover, the two N atoms of the quinazoline can form H-bonds with EGFR, which will produce significant contribution to biological activities. The calculated nonbonded interactions between anilinoquinazolines and EGFR, as well as the information obtained from the predicted complexes, can interpret the structure-activities of the inhibitors well, which can afford us important information for structure-based drug design.

从模拟结果得到的抑制剂和靶酶之间的相互作用模式表明范德华相互作用、疏水相互作用以及氢键相互作用对抑制剂的活性都有重要的影响，抑制剂的苯胺部分位于活性口袋的底部，能够与受体残基的非极性侧链产生很强的范德华和疏水相互作用，抑制剂双环上的取代基团也能和活性口袋外部的部分残基形成一定的范德华和疏水性相互作用，而抑制剂喹唑啉环上的氮原子能和周围的残基形成较强的氢键相互作用，对抑制剂的活性有较大的影响，计算得到抑制剂和靶酶之间的非键相互作用能以及抑制剂和靶酶之间的相互作用信息能够很好地解释抑制剂活性和结构的关系，为全新抑制剂的设计提供了重要的结构信息。

On the other hand, when the radical center is located at the 2-position of bicyclic cyclobutylcarbinyl radicals, ring opening pathway is favored unless a radical-stabilizing substituent is placed in the cyclobutyl ring at the bridge position.

另一方面，当自由基中心位于双环环丁基甲基自由基的2-位时，开环过程占主导地位，但是在双环的桥位上存在能够稳定自由基的取代基时，重排主要进行扩环反应。

The second chapter studies the spectral radius of unicyclic graphs given order and edge independence number, the spectral radius of bicyclic graphs.

第二章，研究了给定阶和边独立数的单圈图的谱半径，研究了双圈图的谱半径。

For unicyclic graphs and bicyclic graphs, we showed that the nullity set both are [0,n - 4](n ≥ 5 for unicyclic graphs and n ≥ 6 for bicyclic graphs).

对单圈图和双圈图，我们证明了零维数集均为[0，n-4](单圈图n≥5，双圈图n≥6)。

The acetate bicyclic guanidine has the above structure and is synthesized by a direct reaction of bicyclic guanidine and acetic acid in a catalyst-free aqueous solution.

所述的醋酸双环胍具有如上结构，是由双环胍与醋酸在无催化剂、水溶剂中直接反应合成。

Due to the strong tension in conformationally restricted bicyclic molecules and strong steric hindrance, the yields of bicyclic isonucleosides were low.

发现由于构象受到限制和强的空间阻碍作用，碱基与化合物19直接缩合可产生双环异核苷，但收率较低。

A novel type of caged bicyclic phosphorous functionalized silsesquioxane was synthesized from caged bicyclic phosphorous quadridentate silicon complex in the presence of tetramethylammonium hy- droxide. The product was confirmed by FTIR, 29Si MAS NMR, MS and XRD spectra.

以双环笼状含磷四配位硅为前驱体，四甲基氢氧化铵为催化剂反应得到具有高度对称结构的双环笼状磷酸酯取代倍半硅氧烷，通过红外光谱，29Si固体核磁共振谱，质谱和X衍射光谱等手段确定了产物的结构和晶型。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。