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Oculocutaneous albinism type 4 (OCA4) is characterized by hypopigmentation of the skin and hair plus the characteristic ocular changes found in all other types of albinism, including nystagmus; reduced iris pigment with iris translucency; reduced retinal pigment with visualization of the choroidal blood vessels on ophthalmoscopic examination; foveal hypoplasia associated with reduction in visual acuity; and misrouting of the optic nerves at the chiasm associated with alternating strabismus, reduced stereoscopic vision, and an altered visual evoked potential.

疾病特征： 4型眼皮肤白化病（OCA4）的特点是皮肤和头发的色素减退以及所有白化病类型都有的典型的眼部改变，包括眼球震颤、虹膜色素减少而使其呈半透明状、视网膜色素减少而使得脉络膜血管在眼底镜检时可见、与中央凹发育不全导致的视敏度降低以及视神经交叉处路径错误引起的交替性斜视、立体感降低和视觉诱发电位改变。

Reduces pancreatic gland exocrine , used ① fasted and stomach and intestine reduced pressure , reduced the gastric acid and food stimulates the pancreatic juice secretion , and reduced vomit with the distension of the abdomen .

3减少胰腺外分泌，采用了①禁食及胃肠减压，以减少胃酸与食物刺激胰液分泌，并减轻呕吐和腹胀，②质子泵抑制剂静脉给药，抑制胃酸分泌，还可预防应激性溃疡的发生。

The results showed that 1 the tar delivery was reduced on an average of 0.1mg per cigarette when the density of tobacco rod was decreased by 1mg/cm3, 2 the tar delivery was reduced on an average of 0.3mg per cigarette when the ratio of draw resistance of filter tip to that of whole cigarette was increased by 1%, and 3 the tar delivery was reduced on an average of 1.1mg per cigarette by use of the both techniques.

结果表明：烟支密度每降低1mg/cm3，卷烟焦油量平均可降低约0.1mg/支；滤嘴吸阻占卷烟吸阻的比例每提高1%，焦油量平均降低0.3mg/支左右。综合运用上述2种稳定和降低卷烟焦油量的措施，使"群英会"牌系列产品的焦油量平均值下降了1.1mg/支，焦油量稳定在设计值±1mg/支以内。

Based on two algebra Riccati equation method especially the structure of the system Hamilton matrix and system observability theory, the role of invariant zeros in constructing system reduced order controllers was given. That is, by the suitable selection of free parameters of the system H(subscript ∞) controller, some points which were symmetry with the unstable invariant zeros about the imaginary axis became the stable poles of the system controller which were not observable and could be reduced from the system, thus could get further reduced order controller.

基于2代数黎卡提方程方法，特别是系统Hamilton矩阵的结构特点和系统可观测性理论，论述了不变零点在构造系统降阶控制器中所起的作用，即通过选择控制器的自由参量，使某些不稳定的不变零点关于虚轴对称的点构成系统控制器不可观的稳定极点，从而实现了控制器进一步降阶。

Result:As compared with the model group, the effect of small dose group and middle dose group of osteopractic total flavone on TBV% of shankbone increased significantly; the effect of small dose group and middle dose group of osteopractic total flavone on TRS% of shankbone reduced significantly and TFS%, AFS%, MAR, BFR of shankbone reduced obviously; the effect of middle dose group of osteopractic total flavone on OSW and mAR reduced obviously, the effect of small dose group of osteopractic total flavone on them had the tendency of reducing, but there was no statistical significance.

结果 ：对胫骨骨小梁体积百分比的影响，与模型组比较，骨碎补总黄酮小剂量组和中剂量组的TBV %明显增高；对胫骨骨小梁吸收表面百分比的影响，与模型组比较，骨碎补总黄酮小剂量组、中剂量组的TRS %显著降低；对胫骨骨小梁形成表面百分比，活性生成表面百分比，骨小梁矿化率和骨小梁骨生成率的影响，骨碎补总黄酮小剂量组、中剂量组的TFS %，AFS %，MAR ，BFR较模型组皆明显降低；对胫骨类骨质平均宽度和骨皮质矿化率的影响，骨碎补总黄酮中剂量组的OSW和mAR与模型组比较，明显降低；骨碎补总黄酮小剂量组与之相比，有下降的趋势，但无统计学意义。

If the ecosan would be developed there, new industries could be promoted and 50-100 thousands of employing opportunities could be created, incidence rate of diseases could be reduced, 560 thousand cubic meters of methane could be recycled, investment of sanitary toilet could be reduced to an acceptable price, i.e., 600-750 RMB yuan per house, ecological agriculture could be developed, and pollutants discharge could be reduced while ecological security could be guaranteed.

若在该区域推广生态卫生，可能产生社会、经济及环境效益如下：带动新兴产业，增加5~10万的直接就业机会；降低疾病感染率；回收沼气56万立方公尺；卫生厕所投入控制在可接受的600~750元户^(-1)；促进生态农业循环；降低污染物排放、保障生态安全。

All 5 patients of benign polyp were found to have excellent effect after Nd-YAG laser therapy, and so for, there was no recurrence. Two (esophageal cancer 1 and rectal cancer 1) of 19 patients of G-I cancer had excellent results with tumor size reduced over 90% and endoscope could pass through the stenotic area smoothly after Nd-YAG laser treatment. Six (esophageal cancer 2, gastric cancer 4) of them had good results with tumor size reduced 50-90% and patient could take semiliquid food after laser management. Eight patients (esophageal cancer 2, gastric cancer 4, rectal cancer 2) had fair effects with tumor size reduced less than 50%, but the oral intake or stool passage was improved. Three patients (15.8%) refused further endoscopy and laser management because of poor tolerance.

这5例良性息肉经雷射治疗后，肿瘤完全消失且目前无后发现象。19位恶性癌中，经Nd-YAG雷射治疗后，效果极佳（肿瘤大小减少90%以上，内视镜可通过肿瘤狭窄处）者2例（食道癌及直肠癌各1；效果佳（肿瘤大小减少50~90%，且病人可进食半流体食物）者6例（食道癌2，胃癌4）；效果尚可（肿瘤大小减少50%以下，但饮食进步或排便较过去进步）者8例（食道癌2，胃癌4，直肠癌2；3例患者(15.8%)因不能忍受内视镜及雷射治疗之痛苦，拒绝进一步的治疗而失败。

After pretreatment with Ca(NO3)2,W7 and TFP in improving and blocking Ca2+*CaM messenger system, membrane damage in strawberry leaf was relief by Ca(NO3)2treatment, at the meanwhile, salt damage index was reduced, the content of prolinc and chlorophyll were enhanced, Pn, EVAP and GS were improved, ABA content in root and leaf was reduced, the content of ZTJAA, GA and ZT/ABA were enhanced, the content of unaturated fatty acid increased, whereas, saturated fatty acid content in leaf and root was reduced, the rate between unaturated fatty acid and saturated fatty acid and index of unaturated fatty acid were enhanced.

在Ca(NO_3)_2、W7和TFP喷叶预处理促进或阻碍Ca~(2+)·CaM信使系统传导后，发现Ca(NO_3)_2处理能减轻叶片的膜伤害，降低盐害指数，增加脯氨酸含量和叶绿素含量，提高净光合速率、蒸腾速率、气孔导度，降低根系和叶片中的ABA含量，增加ZT、IAA和GA含量和ZT/ABA比值；提高叶片和根系中的UFA含量、U/S比值和IUFA，降低根系和叶片中的SFA含量。

Different treatment regimens had been designed according to different classification.②Properly combined chemotherapy protocols reduced therapy intensity and decreased drug toxicities to patients with standard risk ALL.High dose methotrexate,instead of craniospinal radiation,had become effective phylaxis,and decreased the incidence of extramedullary relapse and CNSL (if indispensably,radiation dose was reduced).This measurement reduced radiation chemotherapy long term side effects and improved survival quality.

化疗方案合理组合在保证疗效的同时对ALL后期治疗降低强度，减少药物毒性，同时改进了庇护所预防措施———采用大剂量氨甲蝶呤，大大减少了髓外复发，使相当一部分患儿放弃以往颅脑预防性放疗，即使需要放疗者也降低了剂量，从而减少放化疗远期毒副作用，提高了生存质量。

The author analyzed total oxygen content, nitrogen content in steel made by typical process and the inclusion composition, change rule, morphology and distribution qualitatively and quantitatively by image analyzer, big sample electrolysis, SEM and energy spectrum analysis. The results showed that final inclusion form was small granule MnS, calcium aluminate, a small quantity of silicate and lumpy Al2O3. By intensifying deoxidation alloying process control in converter, argon blowing and slagging control and desulphuration and calcium reduction operation in refining course and overall-protection casting, the oxygen content was reduced by 20% above averagely, nitrogen content was reduced by about 10% and the inclusion content was reduced by 30%.

通过全O、N分析，夹杂物图像分析仪、大样电解、扫描电镜及能谱分析，定性和定量分析了典型工艺钢种钢中全O、N含量和工序过程夹杂物的构成、变化规律及形态、分布，分析钢中最终夹杂物表现形式主要为小颗粒的MnS、铝酸钙、少量的硅酸盐和块状Al2O3，通过强化转炉脱氧合金化工艺控制、精炼过程吹氩与造渣控制及脱硫和钙处理操作、全程保护浇注，钢水中O含量平均降低20％以上，N含量降低10％左右，铸坯中夹杂物含量降低了30％。

Listen,point and check your answers.

听，指出并且检查你的答案。

Warming needle is one of effective treatment methods for knee arthralgia aggravated by cold,and it is simple,safety,so it should be developed in clinical acupuncture and moxibustion extensively.

但以本院科针灸门诊在2005年1月—2006年6月期间共收治膝痛患者100余例，经过临床的诊断后，其中施以温针治疗的48例，疗效显著，报道如下。1临床资料本组病例48