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Paper 2:Mutation analysis of EDA gene in Chinese families with X-linked hypohidrotic ectodermal dysplasiaX-linked hypohidrotic ectodermal dysplasia(XLHED,MIM305100) is a recessive disease characterized by severe hypohidrosis,hypotrichosis and hypodontia.

论文二X连锁无汗/少汗型外胚层发育不良中EDA基因致病突变鉴定X连锁隐性无汗/少汗型外胚层发育不良(X-linked anhidrotic/hypohidroticectodermal dysplasia，XLHED；MIM305100)是无汗/少汗型外胚层发育不良(anhidrotic/hypohidrotic ectodermal dysplasia，EDA)中最常见的一种，约占95%。

Due to great amount of double bond on rubber chain,a lot of intramolecular reaction occurred in the system,which made the uncontrolled cross-linked system into a controlled cross-linked copolymerization,resulting in chain growth can't go illimitably in cross-linking process.

苯乙烯和二乙烯苯共聚体系是典型的不可控制的交联聚合体系，加入天然橡胶后，通过阳离子聚合方法，生成三元共聚物线团，由于橡胶分子链上含有大量的双键，聚合体系中能进行分子内反应，使不可控的交联聚合体系成为可控的交联聚合体系，其链增长不能无限制进行，从而可以合成可溶解的交联的聚苯乙烯-二乙烯苯-天然橡胶聚合物。

Objective To establish an effective technique in reservation and function reconstruction of a leg, in which all the muscles except gastrocnemius necrosed induced by the delayed necrosis of all the intermuscular vessels, the foot was linked only by skin, fascia and tibia, Methods The leg was linked with foot only by the skin, fascia, caput mediale of gastrocnemius and tibia when all the muscles, intermuscular vessels and fibula were removed.

目的 探索迟发性小腿全长肌间血管全部坏死而导致除腓肠肌内侧头以外小腿肌肉全部坏死，仅以皮肤、筋膜、胫骨连足的情况下肢体保留和功能重建的方法。

The decisive influencing factor of viscosity in carboxyl-methylation was cross-linking reaction. Carboxyl-methylation was the main influencing factor of solubility and swelling capacity in modification of high content amylose starch. The structure and gelatinization property of different amylose content were analyzed with an Olympus Vanox BHS-2 multi-function optic microscope, and the results were as follows. The structure of ordinary cornstarch was different from the high amylose; gelatinization temperature and pH value of starch were affected deeply by amylose content, but had little difference between the gelatinization of high content amylose starch contained 50% and 70% amylose; pH value had much more effect than temperature on the gelatinization of high content amylose cross-linked starch. Monochloroacetic acid consumption, alcohol concentration and pH value influenced the starch carboxyl-methylation. When alcohol concentration was 60%, pH value 10, monochloroacetic acid/starch mass ratio 55%, the carboxyl-methylation of high amylose cross-linked cornstarch had the best result. With the In-Vitro digestibility model and biodegradation experiment, the digestibility and biodegradability of high amylose cornstarch and its modified starch were detected.

采用Brabande粘度测定仪和Olympus Vanox BHS-2型多功能光学显微镜等分析手段对链淀粉含量50％和70％的高链玉米淀粉及其交联和交联羧甲基化淀粉的结构和性质进行了表征和分析，结果表明，普通玉米淀粉结构与含链淀粉50％和70％高链玉米淀粉结构不同；高链淀粉比普通淀粉难糊化，高链改性淀粉糊化受pH值影响较大，受温度影响较小；淀粉的冻融稳定性、透光率、溶解度、膨胀度和粘度受链淀粉的含量和改性的影响，但是，链淀粉含量超过50％时，则链淀粉含量对淀粉的膨胀度和溶解度影响不大；改性淀粉性质的影响因素中，影响粘度主要因素是交联反应，影响透明度、溶解度和膨胀度主要因素是羧甲基化改性；一氯乙酸用量、反应时乙醇浓度及碱性条件都会影响高链淀粉及其交联淀粉的羧甲基化改性效果，制备羧甲基化改性淀粉的最佳工艺是在pH值为10的60％的乙醇浓度介质中按一氯乙酸/淀粉质量比为55％进行取代反应。

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Results In living body observation showed all the experiment mice had the hair loss in the early stage, that last longer time in cross-linked ADMs which combined with granulation tissue formation on the parts of skin embedded ADM. After 4 weeks, the new-type ADMs embedded subcutenously had been detected a longer degradation time and more naturelike neogenesis collagen in compared to the cross-linked ADMs.

结果：所有试验小鼠在早期均有毛发脱失现象，交联型真皮组持续时间长并伴有肉芽组织形成。4周后，新型复合真皮显示组织结构致密有序，降解时间更长；组织相容性及促自体胶原代谢能力均较交联型真皮更为优越。

Adjacent helical chains are racemic. The Ag atom is linked to two nitrogen atoms of the 2-pyridyl and 4'-pyridyl groups from two different 2,4'-bpy ligands as well as to the oxygen atom of the counterion. In 17 and 19, the adjacent helical chains are linked to wavy two-dimensional network structures by the nitrate counterions.

相邻的螺旋链间是外消旋的，Ag 原子与分别来自两个不同2，4'-联吡啶的2-吡啶基和4'-吡啶基的氮原子以及阴离子的氧原子配位，在配合物17和19中，相邻聚合螺旋链被硝酸根离子桥连接起来，变成了一个波浪形的二维网络结构；配合物18是首次通过无桥连配体支持的Ag ××× Ag键将相邻螺旋链连接成二维非穿插的网络结构。

Synchronicity is the occurrence of two events that are not linked causally, nor linked teleologically, yet are meaningfully related.

同步性是指两种既无法以因果关系连结，也无法以目的论连结的事件出现，但却在意义上互相关联。

Anything that would violate our right to think for ourselves, judge for ourselves, make our own decisions, live our lives as we see fit, is not only for ourselves, but for thouse we care about, for our society and for the world, are closely linked to also closely linked to our individualism.we donot argue that american should abandon individualism--that would mean for us to abandon our deepest identity.but individualism has come to mean so many things and to contain such contradictions and paradoxes that even to defend it requires that we analyze it critically,that we consider especially those tendencies that would destroy it from within.

凡是违背我们想为自己的权利，法官对自己作出自己的决定，我们活在我们认为适当的生活，不仅是为自己，而是为我们关心的人，为我们的社会和世界，是密切联系又紧密联系我国利益。辩称美国应放弃个人主义--这将意味着我们要放弃我们最深切身份。但是个人主义有这么多事情，就是这种矛盾和悖论牵制甚至捍卫它要求我们必须认真分析，我们认为，特别是那些倾向性就毁来自。

Diagnosis/testing. A diagnosis of ocular albinism is probable in the presence of congenital nystagmus, iris translucency, and significant hypopigmentation of the ocular fundus periphery in males with normal skin pigmentation and foveal hypoplasia, reduced visual acuity, and aberrant optic pathway projection, as demonstrated by crossed asymmetry of the cortical responses on visual evoked potential. X-linked inheritance is documented by either a family history consistent with X-linked inheritance or the presence of typical carrier signs (irregular retinal pigmentation and partial iris transillumination) in an obligate carrier female.

诊断/检测。对于皮肤色素沉着正常、中央凹发育不全、视敏度降低以及视径投射异常（VEP，表现为视觉诱发电位中皮层反应的交叉不对称）的男性患者，当存在先天眼球震颤、虹膜半透明以及显著的眼基底层边缘色素减退的症状时，可被疑似诊断为眼白化病。X连锁性遗传则以存在与X连锁遗传一致的家族病史，或在一个应当为携带者的女性中存在典型的携带者迹象（视网膜色素沉着不规则以及部分虹膜透射）而被确认。

But this is impossible, as long as it is engaging in a market economy, there are risks in any operation.

但是，这是不可能的，只要是搞市场经济，是有风险的任何行动。

We're on the same wavelength.

我们是同道中人。