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These observations may provide a vaccine strategy for cancer therapy through the induction of the autoimmunity against the molecules associated with tumor growth in a cross-reaction with a single xenogeneic homologous gene and may be of importance in the further exploration of the applications of other xenogeneic homologous genes identified in human and other animal genome sequence projects in cancer therapy.

这些结果提示，通过单个异种同源基因以交叉免疫的方式打破肿瘤生长相关分子的自体免疫耐受是一种新的肿瘤疫苗治疗途径，并显示出进一步探索人类和其他种属的异种同源基因在肿瘤免疫治疗应用中的重要性。

Small intestinal biopsies showed subepithelial collagen deposition with varying degrees of villous atrophy and varying numbers of intraepithelial lymphocytes. Four patients had previous biopsies showing enteropathic changes without collagen deposition. Seven cases were associated with collagenous colitis and 1 also had features of lymphocytic colitis. Three patients also had collagen deposition in gastric biopsies. One case was associated with lymphocytic gastritis. Celiac disease (CD, gluten-sensitive enteropathy) was documented in 4 patients. Five patients made a clinical improvement with combinations of a gluten-free diet and immunosuppressive therapy. Two patients died of complications of malnutrition and 1 of another illness. Clonal T-cell populations were identified in 5 of 6 cases tested. Four of these patients improved clinically after treatment but 1 has died. Collagenous sprue evolved on a background of CD in 4 cases. There was no history of CD in others and these cases may be the result of a biologic insult other than gluten sensitivity.

小肠活检表现为上皮下胶原沉积，绒毛萎缩程度不一，上皮内淋巴细胞浸润数量不等。4例患者以往曾做过活检，表现为其他肠病改变，并没有胶原沉积。7例患者合并胶原性结肠炎，且1例还有淋巴细胞性结肠炎的特征。3例患者胃活检也发现有胶原沉积。1例患者合并淋巴细胞性胃炎。4例患者有乳糜泻（CD，谷蛋白敏感性肠病）病史。5例患者经无麸质饮食和免疫抑制治疗后，临床症状有所改善。2例患者因营养不良合并另一种疾病而死亡。6例患者做了T细胞受体基因重排，其中5例发现有克隆性T细胞群，这5例中有4例治疗后临床症状加重，且1例死亡。4例患者在CD的基础上病发胶原性口炎性腹泻；其余患者无CD病史，他们的发病也许是生物源性损害，而非谷蛋白敏感。

AWARE that historically people have experienced these human rights violations because they are or are perceived to be lesbian, gay or bisexual, because of their consensual sexual conduct with persons of the same gender or because they are or are perceived to be transsexual, transgender or intersex or belong to social groups identified in particular societies by sexual orientation or gender identity

我们意识到：历史上，人们遭受这些违反人权的行为，是由於他们是或被认为是女同性恋、男同性恋或双性恋，由於他们与同性别的人进行双方自愿的性行为，或由於他们是或被认为是变性者、跨性别者或两性人，或属於在性倾向和性别认同上被认为是特殊群体的社会团体

With in situ DNA hybridization, the EBV genomes have been demonstrated in the labial glands of the Sjogren′s syndrome patients (16/28), moreover the elevated content of EBV DNA has been identified in those with more severe destruction of labial glands. It is concluded that EBV, vhich has a normal site of latency at salivary glands in a nonpathogenic state, may be reactivated in Sjogren′s syndrome patients and play a role in the pathogenesis of this disease.

另外，我们用原位杂交方法观察了EB病毒DNA在干燥综合征病人唇腺组织的存在状况，结果发现28例干燥综合征病人中16例为阳性，其中腺泡组织破坏严重者，EB病毒DNA的含量亦高，并且EB病毒主要分布于大量浸润的淋巴细胞中，其次位于腺泡上皮细胞内，少量见于腺泡腔中，以上结果提示，在干燥综合征病人EB病毒处于活跃的复制状态，干燥综合征病人靶器官受损与EB病毒的活跃复制及其诱导的免疫反应密切相关。

The spiny eel , belonging to Perciformes, Osteichthyes, is a kind of little freshwater fish distributed in Southern China. In 1998, Our lab detected XX/XY differentiated sex chromosomes in this specie with karyotypic analysis, and then with chromosomal binding and SC observation, we identified that its two largest metacentric chromosomes were X, Y sex chromosomes in 1999. X, Y chromosomes differ each other not only in the distribution of heterochromatin but also in their shapes, which make them could be recognized directly under the light-microscope without any banding treatment.

刺鳅，属鲈形目、刺鳅科(Perciformes，Mastacembelidae)，是广泛分布于中国南方的小型淡水鱼类。1998年，我室通过核型分析，首次发现该物种具有明显分化的异形性染色体，其性别决定类型为XX／XY型。1999年，本室通过染色体显带、精母细胞联会复合体观察，再次确认刺鳅染色体组中最大的一对中部着丝粒染色体为X、Y性染色体，两者不仅已经出现结构异染色质分布上的不同，同时在外部形态上也存在明显差异，识别特征鲜明，在光镜观察下无需显带即能清晰辨认性染色体。

Oligoclonal expansion T cells could be detected and Vβ21 oligoclonal T cells were identified in all 3 cases.Conclusions The skew distribution and clonal expansion of TCR Vβ subfamily T cells could be found on the patients with CML.

结果 3例病人仅存在3～9个TCR Vβ亚家族T细胞，部分Vβ亚家族T细胞呈寡克隆性增殖，Vβ21的寡克隆T细胞见于全部的3例病人中。

With the help of its structure, this paper points out that the non-commutative finite solvable subsimple group will necessarily be a qualitative element group. And referring to the nature of qualitative element group, it can be easily identified the conditions that the ordered prime divisors in a solvable initial finite subsimple group should meet. Suppose that G is always a finite group.

利用其结构，指出了非交换可解有限次单群必为质元群，从而利用质元群的性质，可以很容易地初步确定了可解有限次单群的阶中素因子之间所必须满足的条件，主要得到下面的一些结论：定理1 G是非交换的可解有限次单群，则G′是G的唯一的非平凡正规子群，并且G′是初等交换p -群，此时| G |= p~n q，|G′|=p~n，。

The signals look like noncontinuous beads on the DNA fiber,which consist of multi-copy and arrange tandemly.Fiber-FISH results with 45S rDNA probe showed that an average signal length is about 3～11μm in many tandem copy sequence(measure number,n=8),so we estimated the size of each copy to be approximately 11～30kb in cotton genome.There are dual signals on each end of the mitosis metaphase chromosomes and pachytene chromosomes hybridized with telomere DNA probe.The signals also look like non-continuous beads on the DNA fiber,the length is about 1～9μm,so we estimated the size is about 4～27kb.The signals almost covered the whole mitosis metaphase chromosomes and pachytene chromosomes of G.arboretum Shixiya 1 hybridized with gDNA probe,the euchromatin zone and heterochromatin zone were identified clearly on pachytene chromosomes,and the signals also look like non-continuous beads.Two BAC clones 150-D-24 and 182-F-9 in DNA BAC library of Pima90 were selected as probe to hybridize with mitosis metaphase chromosomes,pachytene chromosomes and DNA fiber of G.raimondii.

棉花FISH技术系统的应用研究。45S rDNA在亚洲棉石系亚1号中期和粗线期染色体上有两对大的信号，在DNA纤维上信号为非连续的念珠状，多个拷贝串联排列，每个拷贝长度大约在3～11μm，推测每个拷贝的实际长度为11～30kb；端粒序列在亚洲棉石系亚1号中期和粗线期染色体端部都有双点信号，在DNA纤维上信号也为非连续的念珠状，不同染色体上信号长度大约在1～9μm不等，推测实际长度为4～27kb；gDNA信号几乎布满整个亚洲棉石系亚1号中期和粗线期染色体，在粗线期染色体上能明显区分出常染色质区和异染色质区，DNA纤维上的信号均为非连续的念珠状。

Comparing with existing solutions, new method can utilize generators' speed signal measured by wide area measurement systems directly and detailed model and parameter of power system components were not needed. After sphering measurement-data, ICA with maximal negentropy criterion was carried out to obtain feature matrix. By this means high-dimension data of multi-machine perturbed trajectories were reduced to lower dimensions, and coherent generator groups were identified by pattern recognition consequently. Simulation results of 36-bus system with 8-generator and planning northwest China 750 kV power grid show that noise signals and bad data can be eliminated. This method is accurate in identifying coherent generator groups.

与现有方法相比，这种方法不需要获得系统元件模型和参数，而是直接球化广域测量系统(wide area measurement systems，WAMS)提供的发电机电角速度信号，再利用最大负熵准则进行独立分量分析得到特征矩阵，将高维数的多机受扰轨迹数据变换到低维空间，通过模式识别得到分群结果。8机36节点系统和西北750 kV电网规划系统算例表明，该方法能有效消除噪音和坏数据的影响，准确识别出同调机群。

Thereby, fault currents can be distinguished from the inrushes if the improved correlation coefficient between the pre-half and the post-half cycle of the measurand is larger than the setting value.Test results show that all types of internal faults even accompanied by magnetizing inrush can be correctly identified from the inrush with the proposed algorithm. Besides with high reliability , this scheme has satisfying sensitivity.

仿真和动模试验表明，该判据能正确识别各种情况下产生的励磁涌流，在变压器带长线发生内部故障、内部故障与励磁涌流并存及CT特性较差的情况下，仍能快速正确地启动出口动作，具有较好的鲁棒性。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。