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The Earth possibly is one by occupies the major part material stably the counter-flow inner layer as well as occupies the few parts the counter-flow outer layer to be composed, the former is constitutes the Earth quite stable movement, the attraction, the magnetic field and so on the macroscopic phenomenon foundation; The latter constitutes the Earth most to be rich in the change the beautiful semblance, such as: Land, islands, volcano, earthquake, plate movement and so on nature environment with each kind of great phenomenon, eliminate this this also are decide the Earth for the perfectly round spheroid basic reason, because the internal heat circular reactions is from starts, the huge energy finally becomes the Earth good fortune a beautiful rich life the star.

地球可能是一个由较稳定占绝大部分物质的对流内层以及占较少部分的对流外层组成，前者是构成地球比较稳定的运动、引力、磁场等宏观现象的基础；后者则构成地球最富于变化的美丽外表，诸如：陆地、岛屿、火山、地震、板块运动等等自然界环境与各种伟大的现象，除此这也是决定地球为浑圆球体的根本原因，因为内热循环反应是从一点开始的，巨大的能量最终把地球造化成一颗美丽的富有生命的星球。

At the same time, on the base of analysis of the present situation, the development trend and the leading edge technology, the necessity and feasibility about the exploitation of the full hydraulic bulldozer"s sate monitoring and fault diagnosis system is given; According to the structure, working feature and working environment, it works out system schema and system composition; The system is divided into display module, communication module and fault diagnosis module by means of block design, the implementation method and key parameter are also given; In light of the features of the full hydraulic bulldozer, the state monitoring and fault diagnosis platform composed of controller RC6-9 and display DI2/10 is designed based on CAN-Bus and the hardware design is completed; It lists the measured values and state of monitored parameters which should be real-time displayed in monitoring module as well as the data which will be transmitted; Furthermore, On the base of the study of, it gives 34 kinds of constant faults" diagnosis methods; Using BODAS software and DPS software, it compile the program code of the controller and the displayer; At last, this paper design and make the simulation test device of control system of construction machinery, through the experiment, the realizability, the categoricalness, the reliability, the stability and real-time are tested, in addition, the improved methods are given.

本文收集整理了国内外智能推土机研究的相关文献资料，综合分析了国内外智能推土机的研究现状、发展趋势和前沿技术，论证了开发全液压推土机智能系统的重要组成部分&全液压推土机状态监测与故障诊断系统&的必要性和可行性；根据全液压推土机的结构、作业特点和作业环境，制定了全液压推土机状态监测与故障诊断系统方案，确定了系统的结构组成；采用模块化设计方法，将整个系统分成了显示、通信和故障诊断三个模块，给出了各模块功能的实现方法，确定了各模块的关键技术参数：选用RC6-9和DI2／10作为系统的控制器和显示器，用CAN总线搭建了系统的通信平台，完成了系统的硬件设计；确定了系统监测参数和通信数据，对全液压推土机常见故障特征进行了分析，给出了34种常见故障的诊断方法；在BODAS软件和DPS软件的集成编程环境下，编写了控制器和显示器程序；设计并制作了工程机械控制系统模拟试验板，并在此基础上通过多次的程序调试与试验，对所设计的全液压推土机状态监测与故障诊断系统功能的可实现性、完备性、可靠性、稳定性和实时性进行了检验，证实了此系统的可行性，并提出了进一步的改进方案和措施。

Can be solid or cystic, have low T2 signal intensity (due to areas composed of interlacing bundles of spindle cells or collagenous septations), which is considered to be a suggestive feature of the diagnosis.

可以是实性或囊性，T2低信号（由于病变由交错的梭形细胞纤维束或胶原分隔组成），这被认为是有助于诊断的特征性改变。

Anhydrous magnesium chloride may be prepared from materials containing magnesium chloride such as magnesium chloride hydrate, carnallite or bittern by different dehydrating methods of organic solvent distillation or molecular sieve absorption, gas protective heating, discomposing the MgCl2-NH3 complex that can be composed from high boiling-point polar-solvent system...

无水氯化镁制备技术经历几十年不断的探索，取得了一些进步，但彻底改变耗能高、污染腐蚀严重、流程复杂的工艺过程，开发流程简单、低污染腐蚀、低成本的绿色工艺仍然需要更深入的研究。

BACKGROUND: One of the key neuropathological changes in Alzheimer disease is that neurofibrils over phosphorylated cytoskeletal protein composed of entwist together, and the phosphorylation of τ protein can be catalyzed by cyclin dependent kinase 5 (CDK5),however whether the phosphorylation of neurofilaments can be catalyzed by CDK5, as well as its role in the pathogenesis of Alzheimer diseases is less acknowledged.

背景：阿尔茨海默病的主要神经病理学特征之一是由过度磷酸化的细胞骨架蛋白如(o，神经细丝组成的神经原纤维缠结，细胞周期蛋白依赖性蛋白激酶5可催化蛋白的磷酸化，但神经细丝是否可被细胞周期蛋白依赖性蛋白激酶5磷酸化及其在阿尔茨海默病发病中的作用却知之甚少。

P16 gene is composed of two intervening sequences and three exons , and encodes p16 protein , which is the inhibiter of CDK4 and CDK6 . They can together prevent phosphorylation deactivation of pRB , and make the cell cycle blocked in G1 stage. P16 gene promoter region has a great of CpG islands , which can be methylated when some adverse factor appears , and so the genetic transcription of p16 can be inhibited , which leads to gene silencing, cell paraplasm, and tumor generate.

抑癌基因p16编码蛋白P16 ，是细胞周期蛋白CDK4和CDK6抑制剂，它阻止pRB磷酸化失活，使细胞周期阻滞于G1期。P16基因启动子区域富含CpG岛，当受到各种有害因素影响时，容易发生甲基化，从而抑制P16基因转录，导致基因沉默，细胞异常增生，导致肿瘤的发生[5]。

The human cartilages are composed of chondrocyte and extracellular matrix,the form of chondrocytes are hypertrophy and the quantity are less;the ECM of cartilage are compised of type II collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury,the ommilayer injury ofcartilage can be recovered by marrow,but because of without stimulation mechanism,the new tissues are merely fibrocartilages,they can not be coincide with hyaline cartilage in menchanics;the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation,thus,the plerosis of articular catilage can not depend on the proliferation of local chondrocyte.Ever since,people tried their best to find a way to reconstruct articular cartilage.

造成人体关节软骨损伤的原因主要为创伤和关节炎，关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复，但这种修复由于缺乏相应的刺激机制，只能形成纤维软骨，而不能形成符合关节生理、力学要求的透明软骨；单纯软骨部分损伤软骨组织内无血管，软骨细胞迁移迟缓，无法使损伤区域软骨细胞再生，因此，关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte.

造成人体关节软骨损伤的原因主要为创伤和关节炎，关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复，但这种修复由于缺乏相应的刺激机制，只能形成纤维软骨，而不能形成符合关节生理、力学要求的透明软骨；单纯软骨部分损伤软骨组织内无血管，软骨细胞迁移迟缓，无法使损伤区域软骨细胞再生，因此，关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

Iron dragon each composed of two long, and each separately by the leading long, long tail and representative body of the 14 long balls, each 24 long balls by the steel composition, 28 long balls from 28 individual performances, commonly known as二十八宿, should be on the number of days, reprovision has Longzhu, Longmen, cloud film虾兵蟹将, lighting fireworks, dance closely together, can be combined, flexible, convenient and endless changes.

铁龙灯每组由两条龙组成，每条龙分别由龙头、龙尾和代表龙身的14个龙球组成，每个龙球由24个钢圈组成，28个龙球由28个人表演，俗称二十八宿，上应天数，另配有龙珠、龙门、云片、虾兵蟹将、烟火灯光等，舞起来环环紧扣，可分可合，灵活方便，变幻无穷。

Porous asphalt concrete is composed of asphalt mastic, coarse aggregate, thin aggregate, stuff and admixture. Such a combination is expected to fully integrate these materials. In this way, the function of interlocking among particles can be performed, a firm net of porous asphalt framework formed and the ability to resist rut and wear developed. The different mixture results in different effects; the quality is so complicated that the factors that cause damage are multiple. Therefore, it is bothersome to choose one material that can be adjusted to various conditions everywhere, such as the traffic volume, load and the weather. The current study mainly investigates and analyzes the main factor that caused flaws after the roads paved with porous asphalt concrete have been open. The analysis aims to search for the best solutions, promote the quality, prolong its availability and finally reach the purpose of complete use.

多孔隙沥青混凝土依其组成材料由沥青胶泥、粗粒料、细粒料、填充料、添加物等组成，目的是希望藉由以上材料的组合能充分接触，发挥颗粒间互锁作用，形成牢固的连锁网的沥青混凝土架构，发挥粒料本身良好的抗车辙及抗磨损之能力，因添加物的不同所发挥出的效果亦不同，其性质甚为复杂，造成损坏之因素亦属多重性，要择其适用於各地迥异之各种条件，如交通量、荷载及气候环境等因子，极为繁琐，本研究主要探讨及分析已铺筑之多孔隙沥青混凝土铺面，经通车后产生之缺失主要因素，以寻求其最佳解决方案，提升品质与延长使用寿命，进而达到全面使用。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。