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TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周,炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节,另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg,20分钟后踝关节照光,激光波长627.sum,功率密度 100mwcm',照射时间1000秒,能量密度100)/。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径,治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后,治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗,随机治疗一侧膝关节,另一侧作自身对照。兔耳静脉注入I'arrainrelomg/Kg,20分钟后,膝关节用金蒸气激光照射,激光能量密度100)儿旷。24 /J'时后取膝关节滑膜作病理检查,并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果: 1。模型观察:CIA大鼠炎症高峰期滑膜下炎细胞浸润明显,滑膜细胞明显增殖,炎症达到高峰后二周,血管缀形成,并侵蚀和破坏软骨和骨, CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生,滑膜下炎细胞浸润,也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明,各组织对HMME 的吸收速度和吸收量不同,荧光值一时间曲线不同,滑膜组织比皮肤和软骨对 HMME的吸收多,在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明:PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性,但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好,统计学检验差异有显著性。。3_军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少,图像分析结果表明面密度(阳性染色的面积总和与统计视野面积的比值)治疗组小于对照组,统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多,图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组,统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小,与对照组相比,统计学检验差异有显著性。结论:二。CIA、AIA的病理改变类似人类RA,可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同,滑膜组织比皮。

Hexachlorocyclophosphazene was prepared using phosphorous pentachloride and ammonium chloride as raw material, hccp was mixed with Montmorillonite which aimed to decrease MMT.'s hydrophilicity. Solid state reserve cell of Mg│reformed MMT.│polymer gel containing water│graphite was assembled, and cell performance was tested. XRD and IR results show: When mass percentage lower than 9.1%, hccp mixed with MMT to form homophase, hccp phase was observed in the mixture when percentage higher than 9.1%, for hccp specific diffraction peak appears in XRD data, and 1220cm-1 which was assigned to P=N double bond 's expand vibration appears in IR data.

合成了六氯环三磷腈,并用六氯环三磷腈与蒙脱石混合对其改性,期望能减小蒙脱石的吸水性能;组装电池Mg |改性蒙脱石|含水凝胶|石墨片,并测试电池的性能。X射线粉末衍射数据和红外光谱数据表明:蒙脱石容纳六氯环三磷腈的质量分数在4.8%-9.1%之间,可与蒙脱石形成单一物相,但混合质量分数大于9.1%时,改性蒙脱石出现六氯环三磷腈的特征衍射峰,和1220 cm-1的六氯环三磷腈P=N双键的特征伸缩振动峰,证明为蒙脱石与六氯环三磷腈的两相混合。

In the in vivo study, 100 ICR mice were randomly assigned to 5 groups after paired by body weight as following: Group N (negative control group, peritoneally injected by saline daily); Group C (positive control group, peritoneally injected by D-galactose and saline daily); Group L, M, and H (peritoneally injected by D-galactose and intragastric administered with TP at 100, 200, 400 mg/day, respectively). Mice were sacrificed for histology and biochemistry studies after 8 weeks.

在动物体内实验中,选择清洁级ICR纯系小鼠100只,按体质量随机分为5组:阴性对照组每天腹腔注射生理盐水,其余4组每天腹腔注射120 mg/kg D-半乳糖以建立小鼠衰老模型,同时阳性对照组每日以生理盐水灌胃,L、M、H组分别以每日100、200、400 mg/kg TP灌胃。8周后处死小鼠,获取心肌标本进行组织学研究和生化检测。

Patients were randomly assigned to two groups, The one is chronic tonsillitis, the other was obstructive sleep apnea syndrome, Exclusion criteria of chronic tonsillitis included peritonsillar abscess history, bleeding disorders, and any other procedure together with tonsillectomy., Indications of chronic tonsillitis included intraoperative bleeding, operative time, postoperative pain, and return to normal diet were evaluated. Indications of obstructive sleep apnea syndrome included Intraoperative bleeding, operative time, Using spss11.0 software analyzed all the data.

实验设计和观察指标:选择慢性扁桃体炎患者30和鼾症患者30人,慢性扁桃体炎患者不包括伴随扁桃体周围脓肿患者,不包括有血液系统疾病和凝血障碍的患者,同时不包括扁桃体切除手术和其它手术同时进行的患者,鼾症患者不包括有血液系统疾病和凝血障碍患者,慢性扁桃体炎患者观察记录的指标包括手术时间﹑手术中出血量﹑术后疼痛时间和程度和正常饮食恢复时间,鼾症患者记录手术时间和手术中出血量,使用spss11.0软件对所有的数据进行描述性统计分析

By this technology,the com plicated task is divided and assigned to different processing units.

作者中文名:包桂秋;王彦平;刘永和

The bodies provided for under the Plurilateral Trade Agreements shall carry out the functions assigned to them under those Agreements and shall operate within the institutional framework of the WTO.

诸边贸易协定项下规定的机构履行这些协定指定的职责,并在WTO的组织机构内运作。

In this study, 340 pregnant women in the third trimester were randomly assigned to receive inactivated influenza vaccine or the 23-valent pneumococcal polysaccharide vaccine.

在这个研究中,340名孕妇在孕期第三个三个月中被随机的分配接受灭活流感疫苗或者23-价肺炎球菌多糖疫苗注射。

WO3, an interlayer compound prepared by J. W. Johnson (1981) using yellow tungstic oxide hydrate. Suspension of white powdery tungstic acid in anhydrous pyridine yields on standing for 2 wk whiteHW4O13.3H2O. IR and DTA studies revealed the connection between that pyridine polytungstate and white powdery tungstic acid (microcryst.), whose composition may thereby be assigned as H2W4O13.nH2O.

WO3。粉状白钨酸在无水吡啶中放置两周后可得到另一种化学式为(C5H5NH)HW4O13.3H2O的吡啶化合物,经IR和DTA研究可初步说明该化合物与粉状白钨酸之间的联系,并因此推测白钨酸的组成可能为H2W4O13.nH2O。

A total of 56 patients undergoing foot surgery were randomly assigned to receive sciatic nerve block by means of a posterior subgluteal (group subgluteal, n = 28) or a posterior popliteal (group popliteal, n = 28) approaches.

有56名将要进行足部手术的病人被随机的分配为臀下组( n = 28)与腘窝组( n = 28)。

Many of them become enthusiastic devotees of books, poring over the books they are assigned to read.

他们中的很多人都热衷于阅读书籍,认真钻研老师布置他们阅读的书本。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力