查询词典 aryl

This invention provides compounds of Formula; wherein: R is a moiety selected from the group: and n is an integer of 1 or 2; R is selected from hydrogen, amino,-NRR, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, alkynyl of 2 to 12 carbon atoms optionally substituted, halogen, and a 5 to 10 membered heteroaryl ring optionally substituted, having 1 to 4 heteroatoms independently selected from N, O and S; R is selected from hydrogen, alkyl of 1 to 12 carbon atoms optionally substituted, aryl of 6, 10 or 14 carbon atoms optionally substituted, alkenyl of 2 to 12 carbon atoms optionally substituted, vinyl, alkynyl of 2 to 12 carbon atoms optionally substituted and halogen; R is H, alkyl of 1 to 12 carbon atoms optionally substituted, cycloalkyl of 3 to 8 carbon atoms, bicycloalkyl of 5 to 10 carbon atoms or aralkyl optionally substituted; R is OH or -OH; R and R are each independently H or alkyl of 1 to 12 carbon atoms or when optionally taken together with the nitrogen atom to which each is attached form a 3 to 8 membered saturated heterocyclyl ring; R is alkyl of 1 to 12 carbon atoms optionally substituted; or a tautomer or pharmaceutically acceptable salts thereof.

本发明提供式的化合物；其中：R 1 为选自基团和的部分；n为整数1或2；R 2 选自氢、氨基、-NR 6 R 7 、具有1到12个碳原子的视情况经取代的烷基、具有6个、10个或14个碳原子的视情况经取代的芳基、具有2到12个碳原子的视情况经取代的烯基、具有2到12个碳原子的视情况经取代的炔基、卤素和具有1到4个独立地选自N、O和S的杂原子的视情况经取代的5元到10元杂芳基环；R 3 选自氢、具有1到12个碳原子的视情况经取代的烷基、具有6个、10个或14个碳原子的视情况经取代的芳基、具有2到12个碳原子的视情况经取代的烯基、乙烯基、具有2到12个碳原子的视情况经取代的炔基和卤素；R 4 为H、具有1到12个碳原子的视情况经取代的烷基、具有3到8个碳原子的环烷基、具有5到10个碳原子的双环烷基或视情况经取代的芳烷基；R 5 为OH或-OH 8 ；R 6 和R 7 各自独立地为H或具有1到12个碳原子的烷基，或当视情况与其所连接的氮原子连接在一起时形成3元到8元饱和杂环基环；R 8 为具有1到12个碳原子的视情况经取代的烷基；或其互变异构体或医药学上可接受的盐。

The results of the experiments show that substituted aryl ethers that containing nitro group (-NO2) are easy to take place nucleophilic substitution in the alkaline medium and then aryl etherbond is cleaved.

实验结果表明，含-NO_2的取代芳基醚，在碱性溶液中，易发生亲核取代反应，从而使芳醚键断裂。

The analysis of SAR reveals that the activities of target compounds are closely associated with the electron-withdrawing substituents at the para position of 1-aryl-1, 2, 4 -triazoles as well as with the substituents such as sulfonyl and methylthio groups at the 3 position of 1, 2, 4 -triazoles; And the introduction of sulfamoyl moiety at the para position of 5-aryl-1,2,4-triazoles also has significant influence on the anti-inflammatory activity of these compounds.

构效关系分析发现，在三唑环1位芳基的对位引入F、Cl、Br吸电子基团以及3位引入磺酰基和甲硫基，对抗炎活性有重要的意义；在三唑环5位芳基的对位引入氨磺酰基，对抗炎活性有较大影响。

New sulfonyloxadiazolones have the formula, in which A stands for hydrogen, sulphur,-SO-,-SO2- or a group, in which R stands for hydrogen or alkyl; R stands for optionally substituted cycloalkyl, cycloalkenyl or aryl; and R stands for optionally substituted alkyl, alkenyl, dialkylamino or aryl.

本发明涉及式新的磺酰基__二唑酮，其中，A代表氧、硫、－SO－、－SO 2 －或基团，其中R 3 代表氢或烷基；R 1 代表任选被取代的环烷基，任选被取代的环烯基或任选被取代的芳基；和R 2 代表任选被取代的烷基，链烯基，二烷基氨基或芳基。

Synthesized 4-aryl coumarins and quinolin-2(1H)-ones via Pd-catalyzed Suzuki reaction of alkenyl tosylates with potassium aryl trifluoroborates.

该方法结合了对甲苯磺酸酯和氟硼酸钾各自的优势，不仅底物适用性较广，而且反应条件温和。2。

The develop-ment of ligands expands the scope of substrates, improves reaction selectivity and realizes the amination of the cheaper and available aryl chlorides. The application of weak base improves the compatibility of functional groups. Pd-catalyzed amination of aryl halides are used in the synthesis of arylamine.

配体的发展扩展了底物的适用范围，提高了反应的选择性，实现了廉价易得的氯代芳烃的胺化，弱碱的使用提高了官能团的兼容性，因此Pd催化芳胺化广泛应用于合成芳胺类化合物。

Chapter 2 presents our studies on aromatic amide-derived phosphine applied to room temperature Suzuki cross-coupling of unactivated aryl chlorides with aryl boronic acids.

第二章主要研究了芳基酰胺衍生的膦配体在不活泼的氯代芳烃同芳基硼酸在室温下的Suzuki偶联反应中的应用。

We studied the effect of water on the palladium acetate-catalyzed coupling reaction of aryl boronic acid with aryl bromide or acyl chloride in ionic liquid or PEG, and found that water had a remarkable rate accelerating effect on the Suzuki reaction and Suzuki-Type reaction when other reaction conditions were uniform.

研究了水对离子液体或聚乙二醇中Pd2催化的卤代苯或苯甲酰氯与苯硼酸的Suzuki和Suzuki-Type偶联反应收率的影响。

Additionally, the synthesisof the key intermediates, cinnamyl aryl ethers was made an investigation andstudy. This improved synthetic method for cinnamyl aryl ethers may be alsoapplied to many benzofuranoid neolignans precursors.

此外，对关键中间体桂皮基芳香醚的合成进行了较为深入的研究，改良的成醚法可适用于许多苯骈呋喃类新木脂素前体的合成。

This dissertation is mainly focused on the reactivity of methylenecyclopropanes and comprises six parts. 1 The reactions of methylenecyclopropanes with phenylsulfenyl chloride, phenylselenyl chloride and diphenyl diselenide; 2 The coupling reactions of the ring-opening products derivated from methylenecyclopropanes; 3 The palladium-catalyzed ring-enlargement of mono-aryl group substituted methylenecyclopropanes to cyclobutenes. 4 The gold-catalyzed domino ring-opening and ring-closing hydroamination of methylenecyclopropanes with sulfonamides; 5 The Lewis acid-catalyzed reactions of mono-aryl group substituted methylenecyclopropanes with diethyl ketomalonate in the presence of water; 6 The iodobenzene diacetate mediated novel 1,3-dipolar cycloaddition of methylenecyclopropanes, vinylidenecyclopropanes, and methylenecyclobutane with phthalhydrazine.

本论文主要研究了亚甲基环丙烷类化合物的一些化学反应性能，共由以下六部分组成：1、亚甲基环丙烷类化合物与苯硫氯、苯硒氯及二苯基二硒的反应；2、亚甲基环丙烷类化合物开环产物的偶联反应；3、单芳基取代的亚甲基环丙烷类化合物在钯催化剂作用下的扩环反应；4、金化合物催化磺酰胺对亚甲基环丙烷类化合物的串联开环关环氨氢化反应；5、路易斯酸催化亚甲基环丙烷类化合物与丙酮二羧酸二乙酯在有水存在下的反应；6、醋酸碘苯促进的亚甲基环丙烷类化合物、亚乙烯基环丙烷类化合物及亚甲基环丁烷类化合物与邻苯二甲酰肼的新型1，3-偶极环加成反应。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。