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Vibrio cholerae adherence to and colonization in the small intestine are essential step in the pathogenesis of cholera. At least one type of pili, known as TcpA, is required for the colonization process. This paper reports the electron microscopic evidence showing that V. cholerae 01 and 0139 serogroups can express at least 4 types of pili when incubated at 28℃ on AKI agar or CFA (pH6.8). Among the four types, three can be expressed by classical and El Tor strains of Vibrio cholerae 01: TcpA pili are peritrichous,being 7-8nm in diameter, 5-10μm in length, and form bundles of parallel undulating filaments of 0.5-0.8 μm wide and 10-15μm long; Type B are 3-4nm in diameter, up to 2μm long, and of wavy morphology; Type C are 7-8nm wide and 0.5-0.8μm long.

本文通过电子显微镜对01群霍乱弧菌古典生物型和El Tor生物型以及0139群霍乱弧菌研究发现，在培养基AKI和CFA(pH6.8)28℃培养条件下，01群EVC和CVC均可产生TcpA，B型和C型菌毛；0139群霍乱弧菌可产生TcpA和B型菌毛，与01群一致。

In this paper we assume the expected returns of the risky and risk-free assets as well as the covariance matrix of the risky assets are not exactly known, but defined by some known elements, which form the vertices of this polytope. Robust optimal portfolio problems are proposed in the market with and without risk-free asset. And the analytical solutions are given out when the covariance matrix of the risky assets are exactly known.

本文假设风险资产和无风险资产的收益以及风险资产的协方差矩阵不是完全确定的，其相关参数属于某个已知的凸多面体，分别在市场不存在和存在无风险资产的情况下定义了稳健最优投资组合问题，并在协方差矩阵确定的情况下给出了问题的解析解。

The fracture reasons of high strength PC steel wire are analyzed, it's considered that center segregation, central cavitation, poriness and inclusion are the metallurgical reasons which lead to the facture of PC steel wire and in the rolling process, differential coping quality, microcrack caused by surface defect, abnormal microstructure caused by burnt and improper cooling velocity, the ears on the head of the wire, overlapping of the wire rod itself are the main reasons which lead to the facture of PC steel wire. At the same time, inappropriate pickling, differential phosphorization quality, the bad heat treatment quality, the generation of crack in the improper drawing and transverse crack caused by abnormal laying of the drawing die are also the reasons of the cracking of PC wire.

对高强度PC钢丝断裂原因进行了分析，认为连铸坯的中心偏析、中心缩孔、疏松和夹杂是导致PC钢丝断裂的冶金原因；轧制过程中，较差的修磨质量、表面缺陷导致的微裂纹，过烧以及不适当的冷却速度导致的非正常显微组织，盘条头部的耳子、盘条本身折叠是导致PC钢丝断裂的主要原因；同时，不恰当的酸洗、较差的磷化及热处理质量、不适当拉丝裂纹的产生、拉拔模具安放不正导致的横裂也是PC钢丝断裂的原因。

At least half of patients with X-ALD are adults with somewhat milder manifestations, and women who are carriers may become symptomatic. X-ALD is often misdiagnosed as attention-deficit/hyperactivity disorder in boys and as multiple sclerosis in men and women, and is not an uncommon cause of Addison disease;(2) the incidence of X-ALD, estimated to be 1:17 000 in all ethnic groups, approximates that of phenylketonuria;(3) noninvasive and presymptomatic diagnosis and prenatal diagnosis are available; family screening and genetic counseling are key to disease prevention; and (4) new therapies, applied early, show promise.

至少1半的X-ALD为成年病人，表现较轻，而作为携带者的女性也可发病。X-ALD在男孩常误诊为注意缺陷/多动综合征，男女可误诊为多发性硬化，并且也是Addison病的病因；(2)据估计X-ALD发病率为1：17 000，类似于苯丙酮尿症；(3)可进行无创性、症状前诊断和产前诊断；家系筛查和遗传咨询是疾病预防的关键；(4)早期采用新的治疗方法非常具有前景。

At least half of patients with X-ALD are adults with somewhat milder manifestations, and women who are carriers may become symptomatic. X-ALD is often misdiagnosed as attention-deficit/hyperactiity disorder in boys and as multiple sclerosis in men and women, and is not an uncommon cause of Addison disease;(2) the incidence of X-ALD, estimated to be 1:17 000 in all ethnic groups, approximates that of phenylketonuria;(3) noninasie and presymptomatic diagnosis and prenatal diagnosis are aailable; family screening and genetic counseling are key to disease preention; and (4) new therapies, applied early, show promise.

至少1半的X-ALD为成年病人，表现较轻，而作为携带者的女性也可发病。X-ALD在男孩常误诊为注意缺陷/多动综合征，男女可误诊为多发性硬化，并且也是Addison病的病因；(2)据估计X-ALD发病率为1：17 000，类似于苯丙酮尿症；(3)可进行无创性、症状前诊断和产前诊断；家系筛查和遗传咨询是疾病预防的关键；(4)早期采用新的治疗方法非常具有前景。

In this study, the genomic structure and regulatory elements of ApoD from 10 representive species including protozoan, invertebrate, protochordate and vertebrate were analyzed and compared. The genomic structure of ApoD is less conserved in organisms from protostome to deuterostome invertebrates, while it is highly conserved among chordates including amphioxus and verebrates. All four conserved cysteine residues are present in amino acid sequence of deuterostome ApoDs, while there are only two cysteine residues in amino acid sequence of protostomes ApoD. Structure divergence between protostome and deuterostome ApoD proteins suggests their function difference. The majority of regulatory elements are present in nearly all organism ApoD genes ranging from unicellular protozoan to mammals, suggesting that ApoD plays a very fundamental role, and possesses a conserved regulatory mechanism. However, there also exist some specific regulatory elements, which are present only in certain species and may perform some special roles.ApoD mRNA expression in murine NIH/3T3 fibroblasts exposed to various stresses such as as hydrogen peroxide and UV light shows dose-dependent increase. And a fly homolog of ApoD, Glial Lazarillo, whose overexpression results in increased resistance to hyperoxia as well as a extension of lifespan under normoxia and resistance to starvation without altering lipid or protein content.

本文首先从生物信息学角度对分属于原生动物、无脊椎动物、头索动物和脊椎动物类群的10种动物ApoD的基因结构及调控区的调控元件进行分析及比较，发现：(1)ApoD基因外显子-内含子结构从原生动物草履虫到原口动物再到后口动物海胆的进化过程中不保守，但在分析的几种脊椎动物中相当保守；(2)文昌鱼ApoD基因扮演从无脊椎动物到脊椎动物承上启下的角色，可能代表了脊椎动物ApoD基因原型；(3)四个半胱氨酸保守位点在后口动物中都存在，而在原口动物中只存在两个，原口、后口动物ApoD蛋白一级结构上的差异反映蛋白功能上可能也存在一定差别；(4)调控区大多数主要调控元件为不同动物共有，说明ApoD主要功能及其表达调控在进化中相当保守；(5)ApoD基因个别调控元件是随着物种进化而出现并开始发挥相关作用，如SF-1；还有一些调控元件在进化过程中还没有发现其规律，这说明ApoD某些功能和基因表达调控模式可能因物种不同而存在一定的差异。

The teeth are all the same, the noses are all the same (except Diane von Furstenberg's), the tits are all the same, and no doubt the pudenda are all shaved in the same pattern.

牙齿是一样的，鼻子是一样的，胸是一样的，甚至连私处也都剃成同样的样式。

The lung arterial smooth muscle cells are pycnosis, nuclear membrane spaces are enlargement, some mitochondrias are diminution, somes are swelling.

冬凌草甲素组可以发现肺小动脉平滑肌细胞核固缩，核膜间隙增大，线粒体浓聚，部分线粒体肿胀。

Itochondrial matR gene sequence analysisIn the strict consensus tree of matR, the topological difference observed is little. Magno-liales, Rosales and Ranales are on the base of the tree, their relationships are unclear in MP, but in BI Ranales and Rosales are closest and they are the sister groups of Magnoliales, while all the three orders is the sister group of Laurales.

P法中木兰目、蔷薇目和毛莨目都位于基因树的基部，之间的关系没有得到解决；而BI法中毛莨目和蔷薇目关系最近，和木兰目聚在一起共同组成樟目的姐妹群。

Unfortunately,the same mental dynamics that tell us to look toward the future will only repeat themselves so that "someday" never actually arrives,John Lennon once said,"life is that happening while we'rebusy making other plans."When we're busy making other plans,our children are busy growing up,the people we love are moving away and dying,our bodies are getting out of shape,and our dreams are slipping away.

约翰列农曾经说：&生活就是我们忙于制定计划时所发生的事，&但我们忙于制定其他计划，我们的孩子忙于成长，我们所爱的人之远离、并撒手人寰，我们的体型走样了，我们的梦想消失了。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。