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There are differences in upper lip and mentolabial sulcus. For class III malocclusion there are significant differences in lower lip and mentolabial sulcus. There are differences in subnasale . Campared with the facial soft tissue thickness of class II malocclusion , for class III malocclusion there are significant differences in lower lip. There are differences in subnasale and upper lip.

与安氏Ⅰ类错合患者相比，安氏Ⅱ类错合患者的颅面部软组织覆盖厚度在鼻底部有显著性差异，在上唇和颏唇沟有差异；安氏III类错合患者的颅面部软组织覆盖厚度在下唇和颏唇沟有显著性差异，在鼻底部有差异；安氏Ⅱ类错合患者的颅面部软组织覆盖厚度与安氏III类错合患者相比，在下唇有显著性差异，在鼻底部和上唇有差异。

The clinical characters of oligodontia concluded from this study are following:(1) There is significant difference that more teeth absent and more existent teeth anomalies in patients of oligodontia/S group than in patients of oligodontia/I group, and the peg-shaped upper lateral incisor is the most frequently affected teeth with shape anomaly.(2) Both of the two groups have no significant differences in number of teeth missing between maxilla and mandible as well as that between left and right side.(3) The distribution of teeth missing is bilateral symmetry in both groups, but the frequency of teeth lost are different: excluding the third molar, in oligodontia/I group, the lower second premolar is the most frequently congenitally missing tooth followed by the upper lateral incisor, while in oligodontia/S group, the most frequently missing teeth are mandibular canine and maxillary lateral incisor. Nevertheless, the first molars are the most stable teeth in both groups.(4) In oligodonita/I group, the mean mesiodistal dimensions of all type of existent teeth are significantly smaller than normal value. It is implied that oligodontia is not an isolated phenomenon, but is related to a complex of other dental changes.

对于口腔多个恒牙先天缺失的临床特点有以下初步结论：(1)综合征型先天缺牙患者较单纯型先天缺牙患者恒牙缺失数目更多，平均分别为23.9个和14.9个，且现存牙齿有更多的形态异常，分别为7／10例（70％）和6／22例（27.3％），其中最常见的是上颌侧切牙畸形；(2)两种类型的多个恒牙先天缺失患者的缺牙数目在上下颌及左右侧之间均无差别；(3)两种类型的多个恒牙先天缺失患者在缺失牙位上均呈对称分布，但在具体牙位上有所差异：不计第三磨牙，单纯型先天缺牙最常缺失的牙位是下颌第二双尖牙、其次为上颌侧切牙；而综合征型先天缺牙最常缺失的牙位是下颌尖牙和上颌侧切牙；无论何种情况，第一磨牙均为牙列中最稳定的牙齿；(4)在单纯型先天缺牙患者中，现存恒牙的牙冠宽度较国人正常值偏小，差异显著，提示牙齿形态与多个牙先天缺失有一定相关性。

The conclusions are as follows:(1) Neologisms in each Huayu region can be classified into two major categories:self-originated and others-originated,among which the new-born words are "absolute new words" and the inherited word are "relative new words",and there are also others-originated elements in the morphemic and sense systems of new words;(2) Variation can be seen in the morpheme,formation,building and sense of new words in Huayu regions,besides individuals of new words;(3) Aggregation of current new words and compound words with one common morpheme and a same construction,together with the aggregation of synonyms and that of different senses in polysemies,reflect the relevance of the systems of new words in Huayu regions in their variation;(4) Regular participation of hinting sense of a formation element in forming and building new words is an important way of producing new sense of morpheme,and an important reason for the current emergence of words with more than one new senses;(5) Compared with ordinary words,the productivity of ways of word formation in forming new words both in general and of a particular class will change and new ways of word formation appear in Huayu regions;(6) The semantic collocation of the verbal morpheme of new verbs in a phrase has a great influence on the location of its structural center,and the complex syntactic behaviors of new verbs are related to the different processes of argument integration;(7) The processes of building new words with the same meaning differ in levels of approaches to motivation cognition,perspectives of motivation cognition,morpheme motivation and morpheme expression,etc.;(8) The lexical interaction in Huayu regions results in lexical subsystem intersections of current new words across two,three and four regions.

本文的主要结论是：(1)各华语区新词均可分为&自源新词&和&他源新词&两大类，其中的新生词和传承词分属&绝对新词&和&相对新词&，新词语的词素、词义系统中也含有他源成分；(2)除词语个体外，华语区新词在词素、构词、造词、词义等方面均体现了某种程度的变异：(3)通用词语聚合、同素同构词聚合、同义异形词聚合与一词多义聚合集中反映了各华语区新词语系统在变异中的关联；(4)构词单位经常提示词义参与构造新词是产生新语素义的重要途径，也是当代多新义词现象的重要成因；(5)相对于一般词语，构词方式在新词语中的总能产性和在某一词类中所体现的能产性都有所变化，华语区也产生了新的构词方式；(6)新动词的动素在短语中的语义搭配对结构核心的位置有很大影响，新动词的复杂句法表现与不同的论元整合过程有关；(7)同义新词造词过程的差异包括理据认知途径、理据认知角度、词素理据和词素表达等不同层面；(8)华语区的词汇互动形成了双区、三区和四区通用新词等词汇子系统交集，作为华语核心，普通话所含纳的通用词语多于各区域变体。

Moreover, the actual allele frequency of most varieties deviates far from Hardy-Weinberg equilibrium. All PPB、na 、I、h、Gi and Fst have proved to be the references to elucidate that ISSR is a most powerful tool to analyze genetic diversity, compared with the RAPD marker and the allozyme marker is less strong ordinally. We could divided the 70 samples into A, B, C, D and E five groups using three methods according to genetic distance clustering. There is a bit displacement for few varieties in different clustering maps, but the most are similar to morphological analysis despite that there is still a great difference among cultivars in the same one group. The above results imply that the three methods have the different sensitivity and resolution in genetic distance analysis of close varieties. The Mantel test indicates that the results from the three kinds of markers have the significant correlation, which demonstrates that the number of the used three kinds of markers is enough to exactly detect the diversity of all 70 samples to ideal extent. And these methods can be used to evaluate the diversity of the whole group using the miscellaneous samples instead of the individual sample, of the Gerbera jamesonii are mainly from tissue culture plants. In conclusion, the above study results provide a reference for the application of three kinds of molecular markers to molecular marker-assisted breeding of flower. 2. The genetic diversity among the eight introduced cut-flower varieties of Ranunculus asiatica was analyzed by the ISSR markers. Based on the genetic clustering tree, all the colorful flower varieties are clustered into one group, and the white flower varieties into another group. Moreover, among the former group the yellow flower varieties are clustered into one sub-group, and the reddish flower varieties, such as rose color, pink, nacarat, are clusetered into another sub-group.

由三种分子标记的分析结果可以看出，等位基因平均值、观察杂合度、Fis值、Fit值皆较高，表明非洲菊等位基因较丰富，杂合基因偏多，且绝大部份品种的实际等位基因频率在品种内偏离了Hardy-Weinberg equilibrium；PP8、na、Ⅰ、h、Gi及Fst皆表明，ISSR检测遗传多样性的能力最强，其次是RAPD，等位酶最低；根据遗传距离进行聚类，三种方法都把70个品种分成A、B、C、D、E五个大组，每一组中除少数品种发生位移外，大部份品种分类结果相似，且与形态分析结果有相似性，但在每一组中，品种间的聚类差别较大，表明这三种方法在近距离品种间检测遗传变异时灵敏度及分辨力不同；Mantel检测表明，三种标记的分析结果有显著相关性，表明所用的三种分子方法的标记数量已经可以相对无偏地检测到70个品种间遗传变异；非洲菊为组培苗，三种标记的检测结果皆表明，混合样品可以作为个体样品的代表，对整个居群的遗传多样性进行评价；这些研究结果可为三种分子标记方法在花卉分子辅助育种中的进一步应用提供借鉴。

Unitary linear regression is done between w~e、 w~ρ、 e~ρ、w_L~w_P. For α_v 、 C_ c between w、ρ、 e、 w_P in eastern China, unitary linear regression is done to silty clay as well as multivariant regression with coefficient iteration method and least-squares procedure are done to all kinds of soil, and the two results are compared. Unitary linear regression and multivariant regression are done to c_q、φ、 c_d、φ_d between e and I_P. Unitary linear regression and multivariant linear regression are done to napierian logarithm of q_u between e 、 I_L、 w_P and w_L, then the equations of regression are checked with other parameters.

对物理指标含水量～孔隙比、含水量～湿密度、孔隙比～湿密度、液限～塑限作了一元线性回归；对华东地区粉质粘土的压缩系数、压缩指数和含水量、湿密度、孔隙比及塑性指数作了一元线性回归；对华东地区所有土类的压缩系数、压缩指数和物理性质参数用系数迭代法和最小二乘法作了多元线性和非线性回归，并对两种方法得到的回归结果作了比较；作了快剪强度指标和固结快剪强度指标关于孔隙比和塑性指数的一元线性回归和多元线性及非线性回归；对无侧限抗压强度的自然对数值和孔隙比、液性指数、液限及塑限作了一元和多元线性回归，并用其它工程的参数对回归方程进行了检验。

By above research, the following results are obtained.(1)The extracting module of aero-radioactive thematic information is integrated with ENVI, the remote sensing image processing software;(2) Based on the IDL, the computer program modules extracting following uranium thematic information have been developed, including initial uranium contents, active uranium contents, uranium migration coefficient, uranium information strengthen, uranium D-value and variance Ratio etc, al. Some of kalium special information extracting modules are also developed;(3)Based on the IDL, the aero-radioactivity information multi-parameter focus analysis module is developed;(4) It is proposed that a lots of phenomenon of uranium immigrating exist in Keping-Kuche are in the Neocene period. Because of the uranium pre-enrichment, the areas with high uranium content were formed in Neozoic and Quaternary. The above migration uranium are also the abundant source for uranium ore-forming in favorable strata of Mesozoic and Cenozoic system;(5)There are obvious uranium immigrating and enrichment in Eastern Portion of Keping Block Uplift, Yinate-Laolongjiang, and Qidaoban-KuChe.

通过上述研究，取得了如下成果：(1)实现了航放专题信息提取模块与ENVI遥感图像处理软件的无缝集成；(2)基于IDL语言开发了初始铀含量、活性铀含量、铀迁移系数、铀信息增强、铀差值方差比等航放铀专题信息，钾专题信息提取处理程序；(3)基于IDL语言开发了航放信息多参数聚焦分析处理程序；(4)发现柯坪-库车地区在晚第三纪开始出现了大量的铀迁移富集现象，不仅使上第三系、第四系沉积时因铀的预富集而形成铀含量高场区，而且也为研究区中新生代有利目的层的铀成矿提供了铀源条件；(5)研究认为，研究区柯坪断隆东段，英阿特-老龙江，七道班-库车等三个区块存在明显的铀迁入富集。

There exits several MDO algorithms. But they are in our opinion either nonefficient or complicated. So we devised an algorithm called Subspace Approximation Optimization . In the SAO algorithm, the whole system is decomposed into one system-level optimization and several disciplinary optimizations so that a large and complicated problem can be divided into several easy-solving sub-problems. The coupling relationships and the coordination among disciplines are presented by equality constraints and these equality constraints are assigned to relevant disciplines. The optimums of design variables in system level optimization are transferred to discipline level optimization. The optimums of design variables in discipline level correspond to the point that is the nearest to the optimums of design variables in system level. If the optimums of design variables in system level are out of feasible region of discipline 1eve1, linear constraints can be built in the system level optimization using the design variable optimums obtained by the discipline level optimization. The system level optimization would improve the design of the whole system with these linear constraints.

目前，国内外已经发展出了多种飞机多学科设计优化算法，本文的重点是针对协同优化算法的不足，提出了子空间近似优化算法(Subspace ApproximatingOptimization，SAO)，SAO算法中，整个系统的优化问题被分解成一个系统级优化和若干学科级优化，而各个学科之间的耦合与权衡关系则被当作等式约束，这些等式约束将被分配到各个学科级优化中去，系统级优化的任务是寻找整个系统的最优解，而学科级优化的目标函数是以系统级优化分配下来的设计点为圆心的超球半径的平方，因此，如果系统级优化分配下来的设计点在学科级优化可行域内，则学科级优化目标函数为0，反之，则学科级优化的最优点是系统级优化当前设计点距离可行域最近的点。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

For TRO there are a little surfacatants whose effect are not good.In this paper,content of sulfonates and composition of alkyl are decided through right design ;under control reaction conditions different alkylbenzene sulfonates are synthesized;Polyreaction catalyst is developed .non-straight high carbon olefine are made through C9-C12 Polyreaction technolgy;clear composition alkylkenzene is sulfanated in falling-film reactor by SO,product can be adjusted,recipe of the surfacate can be used for super-low interfacialtension with Daqing oil -10-3-10-4mN/m,and stablity is good too.According to method issued by Daqing Develop and Explore Research institute,EOR is over 20% in natural core .

本文研究通过烷基苯磺酸盐组成的正确设计，确定了磺酸盐的当量范围和烷基碳数组成和分布；通过对烷基化条件控制，设计合成了不同碳数的直链和支链烷基苯及烷基二甲苯，并用于制备了相应的烷基苯磺酸盐；研制出了新型的烯烃叠合络合催化剂，采用C_9、C_(12)支链烯烃叠合工艺合成了更高碳数的支链烯烃，并进一步合成出相应的烷基苯和烷基二甲苯；以SO_3为磺化剂，通过对磺化条件的选择和控制，采用已知组成的烷基苯混合物进行膜式磺化反应，使合成工艺得以简化；所得磺酸盐组成确定并且可控，最终配方可与大庆原油形成超低界面张力，达10~3～10~(-4)mN/m数量级，且稳定性良好；以合成的烷基苯磺酸盐为主体形成了三元复合驱配方，室内驱油模拟实验表明，按照大庆研究院对复合驱体系活性剂的评价方法，在天然岩芯上的驱油效率在20％以上。

Tropical montane rain forest was investigated in Mengsong, south-west to Jinghong City ofXishuangbanna region in the south of Yunnan near the border between China and Myanmar. There are 623 species of seed plants belonging to 327 genera and 116 families in this forest. Analysis of areal types shows that 32.8% of the families are of tropical and subtropical type, 23.3% tropical to temperate type, and 18.1% typically tropical type. Areal types at generic level mostly are tropical (81.4%), in which 28.4% are of Indo-Malaysian type and 26.8% are of pantropic type.

西双版纳勐宋的热带山地雨林是一种东南亚热带山地雨林的北缘类型，它在植物区系组成上和群落学特征上是介于热带雨林和南亚热带常绿阔叶林之间的热带山地常绿阔叶林。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。