查询词典 antigen

However, to our knowledge, the ability of the embryo antigen-specific anergic T cells to suppress maternal immune responses to the allogeneic fetus in vivo has been less known.

我们既往研究证实，于孕早期干预B7-1/B7-2协同刺激信号后，与自然流产模型孕鼠相比，正常妊娠模型及孕早期干预协同刺激信号的耐受诱导模型外周CD4+CD25+ T细胞的比例显著升高。

This subset is hyporesponsive and anergic to antigen stimulation. Recently, it has been demonstrated to participate in the immune deficiency in human immunodeficiency virus infection and has close relationship with the development of acquired immunodeficiency syndrome. Meanwhile, the CD4(superscript +)D25(superscript +)Treg is also infected when the human body is invaded by HIV. The CD4(superscript +)CD25(superscript +)Treg will finally be killed by the mechanism of antibody-dependent cell-mediated cytotoxicity. Because of the decrease of the CD4(superscript +)CD25(superscript +)Treg, it can't function as a immune suppressor as a result of the excess of activation of HIV and gradually exhausting of the T cell, which shows that the CD4(superscript +)CD25(superscript +)Treg plays a inhibitory role in the different stages of the development of the HIV as well as different effects in the pathogenesis of AIDS.

它能够抑制自身免疫病的发生和发展，参与肿瘤免疫的调节，同时在感染和移植免疫中也发挥着极其重要的作用。T细胞的这一亚群具有免疫调节和免疫抑制的特性，新近发现它亦与爱滋病的发生、发展关系密切HIV进入人体后，CD4D25调节性T细胞抑制了机体的免疫效应但它也同时被感染，最终由于细胞毒的作用而死亡由于调节性T细胞数量的减少不能有效的发挥其抑制作用，HIV持续的过度活化使得T细胞逐渐耗竭说明在HIV发生、发展的不同阶段Treg细胞可能都发挥了免疫抑制作用，但是却对HIV感染与爱滋病发病的进程产生了不同的效应。

Results: T cell anergy was antigen-specific. The state of T cell anergy can be reversed by PHA, CD3 mAb and PMA plus A23187. IL-2 can prevent the induction of T cell anergy, but it can not reverse the state of un-responsiveness. IL-2 and IFN mRNA can not express in anergic T cells. In contrast, IL-4 and IL-10 mRNA were detectable.

结果：T细胞无能为抗原特异性的，多克隆激活剂PHA、CD3单抗和PMA+A23187可以恢复无能T细胞的活性；IL-2可以阻止T细胞无能的形成，但不能逆转其耐受状态；无能T细胞IL2和IFN mRNA是关闭的，而IL-4和IL-10 mRNA则是开放的。

As a functionally and phenotypically distictive T cell subpopulation,CD4+CD25+ regulatory T cells are anergic and retain their ability to suppress antigen-driven response of CD4+CD25- cells in a contact-dependent manner or through a way of secreting immunosuppressive cytokines such as IL-10 and TGF-β.

CD4+CD25+调节性T细胞是一群表型和功能特异的T细胞亚群，具有免疫无能和免疫抑制两大特性，通过细胞直接接触或分泌抑制性细胞因子发挥对CD4+CD25-T细胞的抑制作用。

TJU103 combined with CTLA4-Ig could induce tolerance of donor CD4〓 T-cell to the given antigen, and the tolerance could be transferred by the anergic CD4〓 T-cell and supernatants.

TJU103联合CTLA4-Ig应用，能够调节Th细胞分化，诱导Th细胞发生免疫偏离，使辅助性T细胞更多地向Th2细胞方向分化，有利于免疫耐受的形成。

Three gastric biopsies were taken within 2-3cm around the pylorus of gastric antra,urease detection,HE fuchsin staining and immunohistochemical analysis of Helicobacter pylori IgG antigen,HBsAg and HBcAg were performed separately.

2例肝病或非肝病因伴有胃病行胃镜检查的患者，取胃窦小弯距幽门周围( 2 - 3 )cm处粘膜 3块，分别做快速尿素酶试验及嗜伊红、品红染色，并行免疫组化检测幽门螺旋杆菌HPlgG型抗原。

Objective:To explore the expression changes of proliferating cell nuclear antigen in oral normal mucosa and recurrent aphthous ulcers.

目的 ：观察增殖细胞核抗原在口腔复发性阿弗他溃疡组织中表达强度及分布情况。

Objective:To explore the expression changes of proliferating cell nuclear antigen in oral normal mucosa and recurrent aphthous ulcers.

s9T-mga0摘要：目的：观察增殖细胞核抗原在口腔复发性阿弗他溃疡组织中表达强度及分布情况。

Objective:To explore the relationship between Fas antigen and apoptotic rates and pathological mechanism of aplastic anemia.

目的：探讨Fas抗原和凋亡率与再生障碍性贫血发病机制的关系。

Immune POF model elicited by immunization in subcutaneous with antigen sourced isotype animal ovaries can cause growing follicles and mature follicles decrease obviously, the morphology of oocytes and zona pellucida abnormal, the adjacent granular cells disorder and atresic follicle increase.

以同种动物卵巢为抗原主动免疫建立的免疫性POF模型可致生长卵泡和成熟卵泡数明显减少，卵母细胞及透明带形态异常，周边颗粒细胞排列紊乱，闭锁卵泡增多，病理损伤随免疫时间延长而加重。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。