查询词典 antifungal

General chapters on immunization and chemotherapy (antiviral, antibiotic, antiparasitic, and antifungal) will be complemented by discussion of common clinical syndromes, including otitis media, pharyngitis, bronchiolitis and pneumonia, gastroenteritis, bone and joint infections, meningitis, and periodic fevers.

关于免疫注射和化学疗法(抗病毒，抗菌，antiparasitic 和antifungal)的一般的章将被普通临床的综合症的讨论配合，包括耳炎媒介，pharyngitis，bronchiolitis和肺炎，肠胃炎，骨头和共同传染病，脑膜炎和定期发烧。

The studies presented here provided the antifungal lead compounds. Because the affinity of the lead molecules for CYP51 was mainly attributed to their nonbonding interaction with the apoprotein, which was different from the azole antifungal agents.

先导分子通过与靶酶活性腔氨基酸残基的非共价键结合产生抗真菌作用，避免与血红素辅基Fe原子发生配位结合，为一类具有新作用机理的非氮唑类抗真菌先导化合物。

The results showed that the best substrate of weight ratio of bran was that grain pieces∶ cornmeal was 2∶1∶1.Most quantities of sporulation and antifungal compound on spore germination of Verticillium dahliae were analyzed.Accumulation of antifungal compound was in direct proportion to the quantities of sporulation in the solid fermentation conditions.The solid ferment...

结果初筛出最佳固体发酵基质配方为麸皮：豆粕：玉米粉比为2：1：1；发酵温度、料水比、pH值、接种量等对菌株产芽孢及其抗菌物质的分泌有明显影响；在固体发酵条件下，芽孢的产生数量与抑菌物质的积累呈正比，以温度为35℃，料水比为1：1.4，pH值为7.0，接种量为10%为菌株最佳发酵条件。

To exploit the highly effective natural antifungal medicaments from sea cucumbers, water-soluble holothurian glycosides from Apostichopus japonicus were isolated and purified, and their antifungal activities were examined.

从冻干仿刺参加工废弃液中分离纯化出水溶性海参皂苷，筛选并纯化出其强抗真菌活性组分，为利用水溶性海参皂苷研制高效抗真菌药物创造条件。

The high inoculum levels increased the bacterial growth and shorten the time for antifungal substance production. The powder of rice, soybean cake, yeast, and wheat bran, CaCO3 and KH2PO4 were better nutrients for the bacteria growth and antifungal substance production. There were two stages during the fermentation process at 30℃. The growth of bacteria increased at the first 24 h and the pH of broth rose, but no antifungal activity was observed until 41 h later and reached to the highest level at 114 h.

基本营养物质的初步筛选试验证明：大米粉、豆饼粉、麦麸、酵母粉和CaCO3及KH2PO4是发酵培养基中最佳的营养物质，可满足抗菌物质产生对碳、氮和矿物质的营养需求。B-903的发酵过程可分为两个阶段：在30℃下，24小时内，细菌数量达最大值，pH值由低向高变化，但此阶段检测不出抗菌物质的活性；第二阶段，培养41小时后，抗菌物质活性开始显露，至112小时后达最大值，pH值也逐渐由高变低。

Results Compound albicanyl caffeate displayed strong antifungal property with MIC 4 μg/ml, while moderate antifungal effects (MIC16 μg/ml)were observed with compounds emodin, resveratrol, 3,4'-difluorostilbene, 2,2'-difluorostilbene and 2,3',5'-trifluorostilbene. Pakyonol, catechin, ampelopsin A, 3,4,4'-trihydroxyl- bibenzyl, 2,4'-difluorostilbene, 4-fluorostilbene,2-methyloxy-4'-fluorostilbene showed lower activity with MIC 32 μ g/ml.

结果化合物albicanyl caffeate对白色念珠菌表现出强的抗真菌活性，MIC为4μg/ml；而化合物大黄素、白藜芦醇、3，4'-二氟二苯乙烯、2，2'-二氟二苯乙烯及2，3'，5'-三氟二苯乙烯显示出中等程度的抗真菌活性，MIC为16μg/ml；双联苄pakyonol、多酚类儿茶素、白藜芦醇二聚体野葡萄素A、3，4，4'-三羟基联苄、2，4'-二氟二苯乙烯、4-氟二苯乙烯及2-甲氧基-4'-氟二苯乙烯显示出较弱的抗真菌活性，MIC为32 μg/ml。

To exploit highly bioactive natural antifungal medicaments from starfish, water-soluble starfish glycosides from Asterias rollestoni were isolated and purified by macroporous resin column and silica gel column chromatography, and their antifungal bioactivities were also examined.

为了分离纯化出具有强抗真菌活性的水溶性海星皂苷，以罗氏海盘车腕为实验材料，利用水抽提方法获得水溶性海星皂苷粗品，依次利用大孔树脂和硅胶柱层析对水溶性海星皂苷进行了纯化，并对其抗真菌活性进行了测定。

Synergetic antifungal effects were observed in the combination of albicanyl caffeate or 3,4'-difluorostilbene and fluconazole, whereas additive antifungal effects were revealed when catechin or resveratrol combined with fluconazole.

当与氟康唑联合时，albicanyl caffeate和3，4'-二氟二苯乙烯显示出协同抗真菌活性，而儿茶素与白藜芦醇显示出相加的抗真菌活性。

The antifungal activities of these materials were investigated and build foundation to develop low poison plant antifungal products. In experiment, polyphenols were extracted by reflux ectraction method which applyed petroleum ether to degrease and methyl alcohol solvent. Phenolic hydroxyl were examined and inspected by colour-developing reaction and the content of total polyphenols was determined by UV-spectrophotometry. Screening test were performed to the antifungal activities of polyphenol extraction by the tube dilution method to the selected ten pathogenic fungus such as Dothiorella gregaria, Rhizoctonia solani, Phyllosticta pirina, and the minimal inhibitory concentration were measured. The column chromatography and thin layer chromatography were applyed to separate and analyse cortex extracts of Dracaena cochinchinensi Lour.

实验部分采用以石油醚脱脂，甲醇为溶剂的回流提取法来提取植物多酚，用显色反应检识酚羟基；采用紫外分光光度法对多酚粗体物进行总多酚含量的测定；选取了聚生小穴壳菌、立枯丝核菌、梨叶点霉等10株常见农林业致病真菌，采用试管液基稀释法对多酚粗提取物进行了抗真菌活性筛选试验，并测定其最低抑菌浓度；采用柱层析法和薄层层析法对其中抑菌效果较好的龙血竭进行分离分析，根据其中3种化合物的光谱数据UV、IR、~(13C-NMR、1H-NMR和MS鉴定其结构。

The current antifungal agents used in clinics usually have severe side-effects, it is necessary to seek for new antifungal agents with known or new mechanisms. China has abundant resources in traditional Chinese medicine, therefore exploition of new antifungal agents therefrom is a feasible way.We have screened antifungal activities of 14 ethanolic extracts from traditional Chinese medicines and 21 natural products by using Saccharomyces cerevisiae GL7 and Prototheca wickerhamii as the model microoranganisms. Among the TCMs tested, Cortex Phellodendri, Flos Caryophylli, Fructus Mume, Rhizoma Coptidis and Radix Sophorae tonkinensis showed high antifungal activity. This study layed certain foundation for the development of new antifungal agents.

为了开发中药资源，从传统中药中寻找有抗真菌活性的天然药物并阐明其作用机理以利于临床应用，论文对14种生药乙醇提取物及21种生药化学成分利用啤酒酵母突变型GL7（Saccharomyces cerevisiae GL7）和威克海姆原藻作为模式菌种进行了抗真菌活性筛选，其中黄柏、丁香、乌梅、黄连和山豆根等有很好的抑菌活性，为进一步研究开发成新的抗真菌药奠定了基础。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失