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After treated with recombinant mouse RAGE/Fc chimera/HMGB1, anti-RAGE antibody/HMGB1, HMGB1 or nonimmune rabbit igG, the phagocytosis was determined by the neutral red dye uptake, the cytotoxicity to L1210 cells was measured with MTT assay, the chemotaxis was determined by use of Costar Transwell cell culture chamber inserts, and the expression of I-A^k MHC class Ⅱ antigen on macrophages was detected by flow cytometry.

结果100μg／L的HMGB1作用于巨噬细胞48h后，巨噬细胞表面受体RAGE表达明显上调（P〈0.01）；HMGB1组巨噬细胞吞噬功能、杀伤活性、趋化活性及I-A^k抗原表达均显著高于对照组、HMGB1＋抗RAGE组与HMGB1＋rmRAGE／Fc组（P〈0.01）。

The patients with allergic rhinitis are characterized by an elevated and prolonged immunoglobulin E antibody response after exposure to ubiquitous, nonpathogenic allergens.

变应性鼻炎患者在接触普通的非致病变应原后，以其体内IgE抗体的升高和延长为特征。

Infection with human immunodeficiency virus is diagnosed routinely by the enzyme immunoassay for HIV-1 antibody; a nonreactive blood sample is designated as negative without further testing.

感染人类免疫缺陷病毒，是常规诊断用酶免疫法病毒1抗体；一个翩翩血液样本指定为负无进一步测试。

This protein reduced antibody titer in mice immunized with BSA. Following the deletion of sCD152, however, there was no obvious inhibitory effect on the primary immune response triggered by the nonrelevant antigen OVA, indicating that sCD152 had an antigen-specific immunosuppressive effect. We designed a new vector, pPIC-HE-sCD152, to get entirely native sCD152 without His-tag.

为了获得既带有纯化配体表位又带有可剪切序列的可溶性sCD152蛋白，我们设计构建了含有His-tag和肠激酶识别切割序列DDDDK的sCD152表达载体pPIC-HE-sCD152，结果这一表达载体在毕赤氏酵母中同样高效分泌表达出目的蛋白，大量纯化后用肠激酶酶切去除His-tag，用以进一步功能实验，初步结果表明具有体外细胞免疫抑制功能。

The dynamic evolution of self and nonself, the presentation of the antigen, and the generation of the antibody are proposed.

分析了计算机病毒的逻辑结构，建立了自体和非自体的演化方程、抗原提呈及抗体生成方法。

And antibody can be absorbed quickly by tumor, can keep clear of quickly in normal inside body organization, noxiousness...

而且抗体能够被肿瘤快速摄取，在体内正常组织中可快速清除，毒性。。。

At the same time, the research provides important theoretical evidence for the further study on the hydrolysable principle of cocaine in human\'s body, for the sake of designing the more active one-celled clone antibody which can catalyze the hydrolyzation of cocaine.

本文用密度泛函的B3LYP方法，在6-31G~*水平上对反应物、产物以及各种可能的中间体和过渡态进行了全参数优化，在同一理论水平上对势能面上的全部驻点进行了振动频率分析(来源：Ac9BCa6论文网www.abclunwen.com)。

EO might play an important role in the pathogenesis of hypertension.Key words Ouabain;Antibody;Hypertension

体内哇巴因含量升高可能是高血压发病因素之一，在血压升高中发挥着较为重要的作用。

By phage display technique, we prepare ouabain ScFv, which could reduce the murine and reserve its affinity of polyclonal antibody.

随后通过噬菌体抗体库制备单链抗体，可大大降低了哇巴因多克隆抗体的鼠源性，而又保留了原抗体的亲和活性，为研制一种新的降压药奠定了基础。

In short, we first found EO played an important role in hypertension in 1k1c hypertensive rats. On this basis, we put forward a plan to prepare a new depressor to direct against EO. Then we proved that ouabain polyclonal antibody can decrease significantly blood pressure in 1k1c rats.

总之，本课题首先在1k1c高血压大鼠中证实EO在高血压的发生中起着较重要的作用，在此基础上我们提出了研制一种针对于EO的降压新药的设想，并在1k1c高血压大鼠中证明哇巴因多克隆抗体具有明显的降压作用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。