查询词典 antibody

Now, CD11a monoclonal antibody, LFA-3/IgG1 fusion protein and TNF-αhave been successfully applied in the immunotherapy of psoriasis, and animal experiments have primarily confirmed the therapeutic effects of anti-granulocyte-macrophage colony stimulating factor IgG1,anti-CD4 monoclonal antibody and anti-complement receptor 3 antibody, which are hopeful to be the breakthrough of psoriasis treatment in the future.

一些新的免疫学研究发现，CD11a单抗、LFA-3/IgG1融合蛋白、TNF-α已经成为银屑病免疫治疗中较为成熟的疗法，而粒细胞-巨噬细胞集落刺激因子单抗IgG1，CD4单抗及补体受体3抗体的治疗作用在动物实验中已得到初步验证，有望为银屑病的治疗提供新的突破点。

Results The serum antibody level reached to 0.71±0.08-0.77±0.06 after genetic vaccine pCD-HCV1(100 μg/mouse) were inoculated into the mice(n=12) three or four times while blank vector pCD-SRα1 could not induce the mice(n=8) to generate antibody response in same way.After the antibody levels in mice(n=8) immunized by pCD-HCV1 had ascended to peak value(0.71), there was no trend of descending during the following 18 weeks of detection(0.68±0.06-0.75±0.07). Specific fragment of HCV cDNA identified by polymerase chain reaction from DNA extracted from the muscles of the mice after pCD-HCV1 had beed inoculated three months.

结果 基因疫苗pCD-HCV1(100 μg/只)3-4次接种小鼠后(n=12)，血清抗体水平达0.71±0.08-0.77±0.06，空载体pCD-SRα1免疫鼠血清抗体阴性；免疫鼠(n=8)抗体水平达高峰后(0.71)，持续检测18周未见下降趋势(0.68±0.06-0.75±0.07)；pCD-HCV1免疫小鼠3个月后，用聚合酶链反应仍可从肌肉组织中扩增出特异性HCV cDNA片段；免疫鼠PBMC对HCV合成肽CP9、基因重组抗原C、E1刺激后均出现增殖反应，刺激指数分别为4.07±1.58、3.88±0.70和3.69±1.30，与pCD-SRα1免疫鼠相比，差异有显著性(P.001)。

Prepare 131I-labbelled anti-CD20 monoclonal antibody using lodogen iodine labelling;(2)Measure the immunity activation of labbelled antibody by means of both cell combine analysis and LDH cytotoxicity detection kit;(3)Evaluate the injury rate of tumor exposed to 131I-chimeric anti-CD20 monoclonal antibody in vitro. The MTT method and the experiment of cell growth control are used;(4)Record the apotosis of Daudi cell using gelose electrophoresis;(5)Learn the inhibition effect of radioactive medication on the marrow. Radiohnmunoimages are taken on various intervals after injection of the labeled antibodies to the nude mice. The distribution of radioactive medication, I31l-labeled antibodies, in the marrow tissue indicates the inhibition effect. Here a B cell non-hodgkin lymphoma model in nude mice is established by us;(6)28-day observation are done in 3 groups of nude mice model.

(1) 用lodogen标记法制备131I-国产人鼠嵌合抗CD20单抗；(2)采用细胞结合分析法和乳酸脱氢酶法细胞杀伤性实验测定131I标记后国产人鼠嵌合抗CD20单抗与靶细胞的免疫活和利结合能力；(3) MTT法和细胞生长抑制实验测定131I-国产人鼠嵌合抗CD20单抗的体外杀瘤活性；(4)用琼脂糖凝胶电泳法研究131I-国产人鼠嵌合抗CD20单抗致Daudi细胞凋亡；(5)建立荷人B细胞淋巴瘤移植瘤裸鼠模型，应用γ计数法检测注射到荷瘤裸鼠体内的131I-国产人鼠嵌合抗CD20单抗的组织分布情况，明确其靶向性；(6)将荷瘤裸鼠分3组进行放射免疫治疗，分别为阴性对照组、131I-国产人鼠嵌合抗CD20单抗组、国产人鼠嵌合抗CD20单抗组。

A new antibody releasing system has been developed by covalently attachingIgG to the biodegradable hyaluronic acid hydrogel via the hydrolyticallyunstable hydrazone linkage, aiming to deliver the antibody of CNS regenerationinhibitors to the injured brain. Furthermore, pH sensitive linkage-hydrozone has beenformed between hydrogel and antibody.

这一将该材料植入成年缺损大鼠的大脑皮层后，该材料具有良好的神经相容性，能够抑制胶质瘢痕的形成，并能诱导神经胶质细胞的迁移进入材料，为轴突的再生提供良好的生物为环境，促进神经轴突长入将改性后的水凝胶。

It was found that the vaccines used did not cause the adverse reactions such as hypersusceptibility and changes of feed intakes, and that 2 times of vaccinations of the vaccines all effectively enhanced the antibody levels, respectively, in which the No.Ⅲ vaccine stimulated antibody as rapid as the first vaccination was done while the No. I and No.Ⅱvaccines did not result in the antibody by the first vaccination. It was concluded that the No.

结果发现，三种供试的高致病性蓝耳病灭活疫苗均未引起供试猪发生过敏反应和采食量变化等不良反应；三种供试灭活疫苗经2次免疫后，均能提高抗体水平，其中供试疫苗Ⅲ在首次免疫后即能有效产生抗体，而供试疫苗I和供试疫苗Ⅱ在首次免疫后不能有效产生抗体。

Results: 36 cases with 22 cases of MSAs and MAAs positive (61%), which MSAs positive rate was 40 percent, the most common MSAs was the anti-Jo-1 antibody (30%), MAAs the positive rate was 28%. Anti-Ro-52 antibody for 18 per cent, and with the anti-Jo-1 antibody highly relevant.

结果：36例患者中22例出现MSAs和MAAs阳性(61%)，其中MSAs阳性率为40%，最常见的MSAs是抗Jo-1抗体(30%)，MAAs的阳性率为28%，抗Ro-52抗体占18%，并且与抗Jo-1抗体高度相关。

After immunization, kinetics of antibody response, isotype of IgG antibody, and antibody responses to the individual components of the chimeric antigen were detected by ELISA. Interactions of the antibodies with native antigens located on surface of merozoite of Plasmodium falciparum were analyzed by indirect immunofluorescent assay.

以ELISA检测免疫血清中特异性抗体的动态变化、IgG抗体亚型及对融合抗原各组分的抗体水平，以间接荧光抗体实验分析免疫血清对恶性疟原虫天然抗原的识别情况。

At the same time it researches that when the pigling is 45 days of age,the titer of titer of antibody of sow is higher and it still has protection ability for the pigling and after being immunized concentrated vaccine and common vaccine the pigling and after of antibody raises from transitory decline and after 25 days of immunity the titer of antibody can not reach the critical protective value.

同时研究了仔猪在45日龄时母源抗体效价较高，对仔猪仍然具有保护力，用浓缩疫苗和普通疫苗免疫后，抗体效价由短暂下降至上升，免疫25d后抗体效价达不到临界保护值以上。

Objective To explore the clinical value of the titer of serum HP antibody in patients with gastric diseases.Methods Serous HP antibody was detected with ELISA and HP was cultured,tested with urase,and stained with Gram method on smears which was observed microscopically and compared with proteus protein-enveloped test.Results ELISA showed high sensitivity and specificity.Conclusion Serous ELISA detection of HP antibody can be used widely in clinical diagnosis and epidemical screening without endoscopy and biopsy.

目的 探索胃部疾病患者血清中的幽门螺旋菌HP抗体滴度的临床价值方法应用酶联免疫吸附试验ELISA法检测HP抗体与HP培养，尿素酶试验和涂片革兰氏染色作镜下形态检查相比较，并同时与变形杆菌蛋白包被测定法作比较结果显示该法具有敏感特异性强的特点结论该法无需常规内镜检查，活检查HP而单纯用血清学检查，可广泛应用于临床诊断和流行病学人群普查

A polyclonal antibody against vitellin was prepared in male rabbits and the specific antibody against vitellin was made through absorbtion by male worm homogenate. After purification, HRP was used to mark antibody, then ELISA was set up to detect vitellin content in the Chrysopa septempunctata fat-body, hemolymph and ovary.

提取了大草蛉的卵黄蛋白，免疫家兔，并将所得抗血清经雄虫匀浆液吸收，获得抗卵黄蛋白的特异抗体，经纯化后，用辣根过氧化物酶标记抗体，建立了ELISA法测定大草蛉脂肪体、血淋巴和卵巢中卵黄蛋白含量的方法。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。