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The methods of theory analyses and digital simulation have been used in this thesis and several schemes of strapdown guidance law based on analyzing the performance of several classical guidance laws have also been present according to the characteristics of strapdown Anti-Radiation homing seeker. The stapdown guidance systems were built for a certain Anti-Radiation missile, adopting acceleration autopilot and the attitude autopilot, and the paper has focus on analyzing the performance of low frequency strapdown Anti-Radiation homing seeker. The Approaches of lead correction and dead-zone relay control were given to improve the guidance precision, and also the increasable observability law was attempt and validate.

本文采用理论分析和仿真实验相结合的方法,在对经典制导律进行理论分析和验证的基础上,针对捷联反辐射导引头的特点,提出了捷联制导律多种设计方案,并以某型反辐射导弹为应用背景,分别采用姿态角反馈自动驾驶仪和过载反馈自动驾驶仪构造了捷联制导系统,重点基于反辐射导引头的低频端特性,开展了捷联制导律的导引性能对比分析工作,提出了应用超前校正和带死区继电控制提高制导精度的方法,并对提高可观测性的捷联制导算法的实现思路进行了尝试和验证。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向,本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作,累计筛选1万多个/次样品,发现10余个活性较强化合物;从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究,分离鉴定了58个化合物,发现6个新化合物和14个抗肿瘤活性化合物;通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究,发现它可能是通过降低G2期重要的转录因子E2F-1,致使细胞周期阻滞在G0/G1期,引起多发性骨髓瘤U266细胞凋亡;开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析,结果表明计算与实验一致。

MTT assay indicated that anti-proliferative activities in HeLa, SHIN3, HOAC-21 and HAC-2 cell lines were closely related to structure, 1,10-seco of eudesmane sesquiterpene lactone resulted in reduced anti-proliferative activity. The anti-tumor activity of isoalantolactone was probably achieved by inducing HeLa cell apoptosis.

提示A-环开环可能是导致桉叶烷型倍半萜内酯的体外抑制肿瘤细胞增殖作用消失或减弱的原因;异土木香内酯抑制肿瘤细胞增殖作用有可能是通过诱导肿瘤细胞凋亡机制而实现的。

In the past, Business card printing and membership card making enterprise anti-electrostatics the most commonly used product is anti-static brushes, but anti-static brushes can only be installed a letoff bodysites, and the effect is not very satisfactory.

畴前,制卡和会员卡制作企业不攻静电最常用的产物是不攻静电毛刷,但是不攻静电毛刷只能安设一个播卷部位,且成果不是很抱负。

In 0~20 cm soil layer, there is a considerable effect of herb plant root system on soil anti-shearing strength. Soil anti-shearing intensity (15.33 kPa) by Medicagosativais highest. Particularly in the 20~40 cm soil layer, Melilotus officinalisand M. sativacan drastically enhance soil anti-shearing strength.

试验表明,在0~20 cm土层4种草本植物根系均可显著增加土壤抗剪切强度,其中紫花苜蓿根系对土壤抗剪切强度的增强作用最大,其增大土壤抗剪切强度值为15.33 kPa;草木樨和紫花苜蓿根系在20~40 cm土层也能明显增大土壤抗剪切强度。

Objective To evaluate diagnostic value of anti-deoxyribonuclease B microtitration test in rheumatic fever. Methods Anti-DNase B antibodies of 87 patients with acute rheumatic fever and 202 rheumatic heart disease patients with rheumatic activity were detected with anti-DNase B antibody microtitration test,and compared with antistreptolysin "O" test.

目的 评估A组溶血性链球菌感染的血清学测定方法对诊断风湿热的临床价值方法采用抗DNA酶B微量法和自制试剂测定急性风湿热87例、活动期风湿性心脏病202例病人血清的抗DNA酶B抗体,与抗溶血素O抗体对照研究。

Suit a wide variety, complete specifications, and has a resistance Ran, moisture, mothproof, anti-corrosion, anti-acid, the effect of anti-alkali.

花色品种繁多,规格齐全、且具有阻然、防潮、防蛀、防腐、防酸、防碱之功效。

Viewed from the angle of maneuvers of the field headquarters of the Eighth Route Army in and around Shanxi, with the national conflicts between China and Japan as the thread and the anti-Japanese battles in North China as the setting--fleshed out with combats, episodes and anecdotes of the General Headquarters of the Eighth Route Army, the Big Three divisions of the Eighth Route Army, military sub-areas and anti-Japanese base areas,"The Eighth Route Army" gives a panoptic, unbiased and vivid account of the history of the Eighth Route Armys anti-aggression war.

八路军》以在中央军委正确领导下的八路军前方指挥部在山西境内及其周边地区的活动为主视角,以中日双方民族矛盾为主线,立足于华北抗战,通过八路军总部,三大主力师,各个军分区,以及敌后抗日根据地等点与面贯穿与辐射,全面、客观、形象地反映了八路军的抗战史,突出了共产党领导下的八路军在抗日战争中发挥的中流砥柱作用,讴歌了中国人民坚强不屈、同仇敌忾、不怕牺牲、敢于胜利的伟大民族精神,雄辩地证明了以毛泽东为首的党中央和中央军委制定的正确的战略方针和政策,艺术性地反映了朱德、彭德怀等八路军总部主要领导人杰出的军事指挥才能,突出地表现了八路军各部首长灵活多变的战略战术,成功地塑造了红军战士赵栓柱、农民王铁锤、护士冯玉兰、归国华侨刘茜茜以及出家人智能和尚等五个栩栩如生的人物。

These three internal fixations of femoral peritrochanteric fracture were differ. For example, Gamma nail is less harmful, better clinical treatment, shorter in shape and stronger in anti-hip inversion. DHS, DCS have a better treatment and are stronger in anti-hip inversion but more harmful and excessive bleeding, and HCS, which is named Minimally Invasive Surgery, is the least harmful, less bleeding, suitable for old patients and the patients of tolerance of poor operation, but poor in anti-hip inversion.

3种不同方法内固定治疗转子间骨折具有各自的特点,Gamma钉具有手术损伤小及良好的临床疗效力臂短对抗髋内翻的能力强;滑动加压鹅头钉具有良好的临床疗效及相对坚强的抗内翻能力,但手术损伤相对较大,失血量较大;空心加压螺钉固定的手术损伤最小,属于微创手术方法,可经皮完成,手术出血少,适用于高龄及手术耐受性差的患者,但抗髋内翻的能力最差。

Native Taiwanese writers tend to embrace such themes as absurdity, insecurity, instability, persecutory delusion, anti-speech-control, anti-imprisonment, anti-institution, and fight for freedom.

双方所运行的轨道是不一样的。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。